Morphology and quantitative changes of transient NPY-ir neuronal populations during early postnatal development of the cat visual cortex

1987 ◽  
Vol 261 (2) ◽  
pp. 165-192 ◽  
Author(s):  
Petra Wahle ◽  
Gundela Meyer
Keyword(s):  
Visual Cortex ◽  
Postnatal Development ◽  
Early Postnatal Development ◽  
Neuronal Populations ◽  
Cat Visual Cortex ◽  
Quantitative Changes

Quantitative changes in long-chain fatty acids during fetal and early postnatal development in rats

1992 ◽  
Vol 262 (1) ◽  
pp. R14-R19 ◽  
Author(s):  
S. C. Cunnane ◽  
Z. Y. Chen
Keyword(s):  
Fatty Acids ◽  
Postnatal Development ◽  
Essential Fatty Acids ◽  
Postnatal Life ◽  
Long Chain Fatty Acids ◽  
Early Postnatal Development ◽  
Liver Triacylglycerols ◽  
Quantitative Changes ◽  
Long Chain ◽  
Chain Fatty Acids

The quantitative importance of triacylglycerol as a source of total essential fatty acids during early postnatal development is reported in the accompanying article. Our objective here was to measure the quantitative changes in individual long-chain fatty acids in specific lipid classes of the carcass, liver, and brain of the developing rat mainly to describe the relative accumulation of long-chain vs. precursor fatty acids. Fatty acids in carcass phosphatidylcholine (micrograms/g) were lower at fetal days 18-21 than at either fetal day 15 or postnatal days +3 to +9. Individual long-chain fatty acids in liver phosphatidylcholine and phosphatidylethanolamine increased markedly by day +3 postnatally, whereas in brain phosphatidylethanolamine, the postnatal increase was delayed to between days +6 and +9. Fatty acids in carcass and liver triacylglycerols increased quantitatively by 10- to 300-fold from fetal day 21 to postnatal day +3 with amounts of both arachidonic and docosahexaenoic acid equaling linoleic acid. The ratios of linoleic and alpha-linolenic acids to respective long-chain products were significantly higher in triacylglycerols, whereas that of stearic to oleic acid was higher in phospholipids. We conclude that, during early postnatal life, oleic, linoleic, and alpha-linolenic acids are required in quantitatively greater amounts in triacylglycerols, whereas stearic acid and long-chain essential fatty acids are required in phospholipids.

Postnatal development of perisomatic GABAergic axon terminals on neurons projecting from area 17 to area 18 of the cat visual cortex

1999 ◽  
Vol 16 (1) ◽  
pp. 35-44 ◽  
Author(s):  
FERNANDO PÉREZ-CERDÁ ◽  
LUIS MARTÍNEZ-MILLÁN ◽  
CARLOS MATUTE
Keyword(s):  
Visual Cortex ◽  
Postnatal Development ◽  
Developmental Stages ◽  
Time Frame ◽  
Projection Neurons ◽  
Area 17 ◽  
Gamma Aminobutyric Acid ◽  
Area 18 ◽  
Axon Terminals ◽  
Cat Visual Cortex

We have studied the postnatal development of presumptive axon terminals (puncta) which were recognized by antibodies to the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and were located on the somata of area 17 neurons projecting to the ipsilateral area 18 of the visual cortex in cats ranging from 7 days of age to adulthood. Projection neurons were retrogradely labeled by injection of horseradish peroxidase conjugated to wheat germ agglutinin into the ipsilateral area 18. These neurons were mainly pyramidal in shape at all the developmental stages examined and the adult distribution of labeled cells was reached by 21 days. Subsequent GABA postembedding immunohistochemistry using high-resolution light microscopy was carried out to study the development of GABAergic terminals on cell bodies of identified projecting neurons in layers II–III. At all ages examined, we found perisomatic GABAergic puncta on these cells. Their density showed a significant increase from postnatal days 7 to 45, and then remained largely constant through adulthood. Since GABAergic puncta are considered the light-microscopic correlate of GABAergic synaptic terminals, our results support the idea of a developmentally regulated increase in the inhibitory activity of local interneurons on area 17 pyramidal neurons projecting to area 18 in the cat visual cortex which occurs within the same time frame as that of the acquisition of the mature operation of these cells.

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