Age-dependent change in exploratory behavior of male rats following exposure to threat stimulus: Effect of juvenile experience

2007 ◽  
Vol 49 (5) ◽  
pp. 522-530 ◽  
Author(s):  
Hiroyuki Arakawa
Keyword(s):  
Exploratory Behavior ◽  
Male Rats ◽  
Dependent Change ◽  
Stimulus Effect ◽  
Age Dependent ◽  
Threat Stimulus

Pigments versus structure: examining the mechanism of age-dependent change in a carotenoid-based colour

2012 ◽  
Vol 82 (2) ◽  
pp. 418-428 ◽  
Author(s):  
Simon R. Evans ◽  
Ben C. Sheldon
Keyword(s):  
Dependent Change ◽  
Age Dependent

Spermatotoxic effects of carbaryl in rats

1996 ◽  
Vol 15 (9) ◽  
pp. 736-738 ◽  
Author(s):  
N. Pant ◽  
R. Shankar ◽  
SP Srivastava
Keyword(s):  
Sperm Motility ◽  
Sperm Count ◽  
Young Male ◽  
Male Rats ◽  
Epididymal Sperm ◽  
Abnormal Morphology ◽  
Age Dependent ◽  
Effect Level

The spermatotoxic effect of carbaryl in adult and young male rats has been examined. Carbaryl 50 and 100 mg/kg b.wt. Male fed 5 d/week for 60 days, caused dose and age- dependent decline in epididymal sperm count and sperm motility, an increase in sperm with abnormal morphology. The dose of 25 mg/kg/d was a 'No observed effect level' for the indices studied. Young animals in comparison to adults exhibited pronounced spermatotoxic effects.

Chlorpyrifos with age-dependent effects in cardiac tissue of male rats

2021 ◽  
Vol 14 ◽  
Author(s):  
Behzad Mesbahzadeh ◽  
Hossein Salarjavan ◽  
Saeed Samarghandian ◽  
Tahereh Farkhondeh
Keyword(s):  
Cardiac Tissue ◽  
Organophosphorus Pesticides ◽  
Male Rats ◽  
Aged Rats ◽  
Middle Aged ◽  
Sod Activity ◽  
Age Dependent ◽  
Oxidative Modifications ◽  
Total Antioxidant ◽  
Male Wistar Rats

: Age-dependent toxic effects of organophosphorus pesticides (OPs) have not fully understood. Current study aimed to investigate the cardiotoxic damage of chlorpyrifos (CPF) by evaluating oxidative modifications in young (2-month old), middle-aged (10-month old), and aged (20-month old) rats. Five mg/kg of CPF was administered orally for 45 days to young, middle-aged, and aged male Wistar rats. At the end, animals were anesthetized and the heart of each rat was dissected for biochemical assay. Malondialdehyde (MDA), nitric oxide (NO), glutathione (GSH), total antioxidant capacity (TAC), and superoxide dismutase (SOD) were assessed in the cardiac tissue of rats. The results indicated an increase in the levels of MDA and NO, and also a decline in the levels of GSH and TAC as well as a decrease in the SOD activity in the heart of aged rats compared with young rats. CPF administration deteriorated these changes in the heart of exposed rats compared with the age-matched controls. Additionally, these oxidative modifications were more severe in aged rats versus other age. In conclusion, advancing age may increase oxidative changes in the heart of animals exposed to CPF. It is suggested that aging can affect cardiac toxicity induced by OPs.

scholarly journals Age-Dependent Change of Tonic Immobility Response in Chicks of a Native Japanese Chicken breed, Tosa-Jidori

2013 ◽  
Vol 50 (4) ◽  
pp. 321-325 ◽  
Author(s):  
Eriko Nakasai ◽  
Hiroshi Tanizawa ◽  
Minani Takawaki ◽  
Kouichi Yanagita ◽  
Shin-ichi Kawakami ◽  
...  
Keyword(s):  
Tonic Immobility ◽  
Chicken Breed ◽  
Immobility Response ◽  
Dependent Change ◽  
Age Dependent

scholarly journals AGE-DEPENDENT EFFECTS OF MELATONIN ADMINISTRATION ON PROSTATIC CYTOSOL ANDROGEN RECEPTORS IN MALE RATS

1986 ◽  
Vol 20 (11) ◽  
pp. 1199-1199
Author(s):  
H Moeller ◽  
K Müller ◽  
B Goecke ◽  
A Attanasio ◽  
D Gupta
Keyword(s):  
Androgen Receptors ◽  
Male Rats ◽  
Melatonin Administration ◽  
Age Dependent

scholarly journals Enhanced Expression of NR2B Subunits of NMDA Receptors in the Inherited Glaucomatous DBA/2J Mouse Retina

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Ling-Dan Dong ◽  
Jie Chen ◽  
Fang Li ◽  
Feng Gao ◽  
Jihong Wu ◽  
...  
Keyword(s):  
Secondary Glaucoma ◽  
Mouse Retina ◽  
Retinal Ganglion ◽  
Protein Levels ◽  
Dependent Change ◽  
Blot Technique ◽  
Elevated Intraocular Pressure ◽  
Age Dependent ◽  
Enhanced Expression ◽  
Nmdar Subunits

DBA/2J mouse has been used as a model for spontaneous secondary glaucoma. Here, we investigated changes in expression of NMDA receptor (NMDAR) subunits and Cdk5/p35/NMDAR signaling in retinas of DBA/2J mice using Western blot technique. The protein levels of NR1 and NR2A subunits in retinas of DBA/2J mice at all ages (6–12 months) were not different from those in age-matched C57BL/6 mice. In contrast, the protein levels of NR2B subunits, in addition to age-dependent change, significantly increased with elevated intraocular pressure (IOP) in DBA/2J mice at 6 and 9 months as compared with age-matched controls. Moreover, expression of Cdk5, p35 and ratio of p-NR2AS1232/NR2A progressively increased with time in both strains, suggestive of activated Cdk5/p35 signaling pathway. However, the changes in these proteins were in the same levels in both strain mice, except a significant increase of p35 proteins at 6 months in DBA/2J mice. Meanwhile, the protein levels of Brn-3a, a retinal ganglion cell (RGC) maker, remarkably decreased at 9–12 months in DBA/2J mice, which was in parallel with the changes of NR2B expression. Our results suggest that elevated IOP-induced increase in expression of NR2B subunits of NMDARs may be involved in RGC degeneration of DBA/2J mice.

Age-dependent change in sensitivity of oestrogen-induced uterine cell proliferation of mice, estimated by incorporation of [125I]iododeoxyuridine

1985 ◽  
Vol 23 (6) ◽  
pp. 1037-1041 ◽  
Author(s):  
N. Terada ◽  
T. Yamane ◽  
Y. Ogasawara ◽  
K. Matsumoto ◽  
Y. Kitamura
Keyword(s):  
Cell Proliferation ◽  
Dependent Change ◽  
Age Dependent

Age-dependent effects of testosterone on spatial memory in male rats

2020 ◽  
Vol 122 ◽  
pp. 104748 ◽  
Author(s):  
Graciela Jiménez-Rubio ◽  
José Jaime Herrera-Pérez ◽  
Hilda Angélica Martínez-Becerril ◽  
Martín Sergio Márquez-Baltazar ◽  
Lucía Martínez-Mota
Keyword(s):  
Spatial Memory ◽  
Male Rats ◽  
Age Dependent

Age-Dependent Change in a Soluble Factor Responsible for Th-2 Type of Help in the Indirect Plaque-Forming Antibody Response

Gerontology ◽  
1983 ◽  
Vol 29 (1) ◽  
pp. 49-63 ◽  
Author(s):  
T. Matsuzawa ◽  
B. Cinader
Keyword(s):  
Antibody Response ◽  
Soluble Factor ◽  
Dependent Change ◽  
Age Dependent

Age-Dependent Replication of Respiratory Syncytial Virus in the Cotton Rat

2002 ◽  
Vol 227 (9) ◽  
pp. 799-802 ◽  
Author(s):  
Spencer J. Curtis ◽  
Martin G. Ottolini ◽  
David D. Porter ◽  
Gregory A. Prince
Keyword(s):  
Respiratory Syncytial Virus ◽  
Age Groups ◽  
Fold Increase ◽  
The Elderly ◽  
Geriatric Population ◽  
Cotton Rat ◽  
Dependent Change ◽  
Age Dependent ◽  
Syncytial Virus ◽  
Viral Titers

Despite the documented disease burden of respiratory syncytial virus (RSV) in the elderly, little is known about the underlying risk factors or pathogenesis of RSV in a geriatric population. This report describes an age-dependent change of RSV clearance in the lung and nose of the cotton rat. Six days postinfection with RSV, lung and nose viral titers were significantly higher in all older age groups as compared with 4- to 6-week old cotton rats (P < 0.05). When comparing the 4- to 6-week old animals to the 15- to 16-month old animals 6 days postinfection, there was over an 800- and 100-fold increase in lung and nose viral titers, respectively. The cotton rat may prove to be a useful model in eliciting mechanisms of severe RSV disease in the elderly.

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