The development of convulsive seizures in the grasshopper mouse (Onychomys torridus)

1975 ◽  
Vol 8 (6) ◽  
pp. 547-552 ◽  
Author(s):  
Richard McCarty ◽  
Charles H. Southwick
Keyword(s):  
2014 ◽  
Vol 2 ◽  
pp. 396-399 ◽  
Author(s):  
DJ Albers ◽  
J Claassen ◽  
M Schmidt ◽  
G Hripcsak

2012 ◽  
Vol 98 (2-3) ◽  
pp. 206-215 ◽  
Author(s):  
Yu-Wen Hung ◽  
Ding-I Yang ◽  
Pei-Yu Huang ◽  
Tzong-Shyuan Lee ◽  
Terry B.J. Kuo ◽  
...  

2017 ◽  
Vol 56 (16) ◽  
pp. 2113-2118 ◽  
Author(s):  
Kenichiro Sato ◽  
Noritoshi Arai ◽  
Aki Omori-Mitsue ◽  
Ayumi Hida ◽  
Akio Kimura ◽  
...  

2013 ◽  
Vol 5 (2) ◽  
pp. 125-129 ◽  
Author(s):  
Faisal Mohammad Amin ◽  
Vibeke Andrée Larsen ◽  
Peer Tfelt-Hansen

PEDIATRICS ◽  
1964 ◽  
Vol 33 (3) ◽  
pp. 431-434
Author(s):  
Sidney Carter

FOR MOST PARENTS their child's first convulsion is a dramatic, frightening event which demands immediate medical attention. The physician, on the other hand, may see the patient after recovery from the attack and may tend to minimize the severity of the situation and assume a wait-and-see attitude before investigation and treatment are initiated. The convulsion is a symptom that indicates a disturbance of cerebral neurones. This disturbance may be the result of underlying organic disease of the brain, either fixed or progressive, or it may be an indication of a functional disturbance related to a circulatory or metabolic disorder. The first attack may be so mild that the child is unaffected but subsequent attacks may be prolonged, or result in status epilepicus, and produce a mild or severe degree of mental impairment. There is considerable evidence to indicate that anoxia associated with convulsions can cause brain damage and for this reason every child who has had a convulsion should be investigated and, with rare exception, placed on prophylactic daily anticonvulsant medication when no specific treatable condition is discovered. EVALUATION The first step in the study of a child who has a convulsion is to document its occurrence. Anxious parents are, as a rule, poor witnesses. Despite this, every effort should be made to obtain a description of the seizure, particularly premonitory symptoms, loss of consciousness, convulsive movements, duration of the attack, and the state of the patient following the attack. In infants breath-holding spells may simulate convulsive seizures. In breath-holding spells there is always a precipitating factor, usually a slight injury or some emotional disturbance which results in violent crying, ending suddenly in respiratory apnea. The cyanosis in such attacks appears before the loss of consciousness and convulsive movements.


PEDIATRICS ◽  
1954 ◽  
Vol 14 (3) ◽  
pp. 269-279
Author(s):  
CHARLES D. MAY

WITHIN the past year a dramatic outbreak of a singular type of convulsive seizures in babies has provided convincing evidence of an essential role for Vitamin B6 in human nutrition under natural circumstances. This is a general review of the circumstances surrounding this outbreak and of the present state of our knowledge of vitamin B6. But it is also important that this episode be considered as a reminder of the complex interrelationships which permeate studies of nutritional factors and as a warning against hasty conclusions. It also serves as an illustration of the hazard in premature or uncontrolled application to human nutrition of isolated fragments of knowledge concerning nutritional factors. The existence of Vitamin B6 was discovered in 1934 by experiments with rats. Symptoms of deficiency of this vitamin were soon described in several species of animals but not in man. Within a few years the chemistry of the vitamin was determined and the synthesis achieved. Considerable information as to the metabolic reactions affected by a deficiency of Vitamin B6 was rapidly accumulated. Only recently, 16 years after the discovery of Vitamin B6, the Council on Pharmacy and Chemistry of the American Medical Association reviewing the status of our knowledge of the role of Vitamin B6 in human nutrition reached only a cautious acceptance of an essential dietary requirement for Vitamin B6 in the human. The original observations which called attention to the problem of unusual convulsions in infants and pointed the way to its solution were made by a doctor in practice, just as were similar observations which led a few years ago to an appreciation of the circumstances producing a deficiency of folic acid in infancy.


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