scholarly journals Engineered nanoparticles interact with nutrients to intensify eutrophication in a wetland ecosystem experiment

2018 ◽  
Vol 28 (6) ◽  
pp. 1435-1449 ◽  
Author(s):  
Marie Simonin ◽  
Benjamin P. Colman ◽  
Steven M. Anderson ◽  
Ryan S. King ◽  
Matthew T. Ruis ◽  
...  

2016 ◽  
Vol 15 (4) ◽  
pp. 923-934 ◽  
Author(s):  
Mohammadreza Kamali ◽  
Ana Paula Duarte Gomes ◽  
Zahra Khodaparast ◽  
Tahereh Seifi


2020 ◽  
Author(s):  
Lungwani Muungo

Engineered nanoparticles are widely used for delivery of drugs but frequently lack proof of safetyfor cancer patient's treatment. All-in-one covalent nanodrugs of the third generation have beensynthesized based on a poly(β-L-malic acid) (PMLA) platform, targeting human triple-negativebreast cancer (TNBC). They significantly inhibited tumor growth in nude mice by blockingsynthesis of epidermal growth factor receptor, and α4 and β1 chains of laminin-411, the tumorvascular wall protein and angiogenesis marker. PMLA and nanodrug biocompatibility and toxicityat low and high dosages were evaluated in vitro and in vivo. The dual-action nanodrug and singleactionprecursor nanoconjugates were assessed under in vitro conditions and in vivo with multipletreatment regimens (6 and 12 treatments). The monitoring of TNBC treatment in vivo withdifferent drugs included blood hematologic and immunologic analysis after multiple intravenousadministrations. The present study demonstrates that the dual-action nanoconju-gate is highlyeffective in preclinical TNBC treatment without side effects, supported by hematologic andimmunologic assays data. PMLA-based nanodrugs of the Polycefin™ family passed multipletoxicity and efficacy tests in vitro and in vivo on preclinical level and may prove to be optimizedand efficacious for the treatment of cancer patients in the future.



2018 ◽  
Vol 18 (11) ◽  
pp. 1040-1054 ◽  
Author(s):  
Veliyath Gopi Reshma ◽  
Santhakumar Syama ◽  
Sudhakaran Sruthi ◽  
Sebastain Cherian Reshma ◽  
Nirmal Suma Remya ◽  
...  




Author(s):  
Chuan-Wang Yang ◽  
Li Yuan ◽  
Hong-Zhi Zhou ◽  
Xin Zhang ◽  
Guo-Ping Sheng

Natural organic matter (NOM) can adsorb onto engineered nanoparticles (ENPs) and form NOM-corona on ENPs-solution interface, thus affecting the performance and ecotoxicity of ENPs in aquatic systems. Nevertheless, the formation...







Talanta ◽  
2021 ◽  
Vol 226 ◽  
pp. 122201
Author(s):  
Andrei R. Timerbaev ◽  
Olga V. Kuznetsova ◽  
Bernhard K. Keppler


Nanomaterials ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1397
Author(s):  
Bishwash Shrestha ◽  
Mohammadamin Ezazi ◽  
Gibum Kwon

Membrane-based separation technologies are the cornerstone of remediating unconventional water sources, including brackish and industrial or municipal wastewater, as they are relatively energy-efficient and versatile. However, membrane fouling by dissolved and suspended substances in the feed stream remains a primary challenge that currently prevents these membranes from being used in real practices. Thus, we directly address this challenge by applying a superhydrophilic and oleophobic coating to a commercial membrane surface which can be utilized to separate and desalinate an oil and saline water mixture, in addition to photocatalytically degrading the organic substances. We fabricated the photocatalytic membrane by coating a commercial membrane with an ultraviolet (UV) light-curable adhesive. Then, we sprayed it with a mixture of photocatalytic nitrogen-doped titania (N-TiO2) and perfluoro silane-grafted silica (F-SiO2) nanoparticles. The membrane was placed under a UV light, which resulted in a chemically heterogeneous surface with intercalating high and low surface energy regions (i.e., N-TiO2 and F-SiO2, respectively) that were securely bound to the commercial membrane surface. We demonstrated that the coated membrane could be utilized for continuous separation and desalination of an oil–saline water mixture and for simultaneous photocatalytic degradation of the organic substances adsorbed on the membrane surface upon visible light irradiation.



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