scholarly journals Discordance between estimated and measured changes in plasma volume among patients with acute heart failure

2021 ◽  
Author(s):  
Jutta S. Swolinsky ◽  
Enkhtuvshin Tuvshinbat ◽  
David M. Leistner ◽  
Frank Edelmann ◽  
Fabian Knebel ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Plasma Volume

scholarly journals Plasma volume status predicts prognosis in patients with acute heart failure syndromes

2017 ◽  
Vol 7 (4) ◽  
pp. 330-338 ◽  
Author(s):  
Akiomi Yoshihisa ◽  
Satoshi Abe ◽  
Yu Sato ◽  
Shunsuke Watanabe ◽  
Tetsuro Yokokawa ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Plasma Volume ◽  
Hazard Ratio ◽  
Volume Status ◽  
Cardiac Events ◽  
All Cause Mortality ◽  
Acute Heart Failure Syndromes ◽  
Mortality Hazard Ratio ◽  
Ideal Plasma

Background: The intravascular compartment is known as the plasma volume, and the extravascular compartment represents fluid within the interstitial space. Plasma volume expansion is a major symptom of heart failure. The aim of the current study was to investigate the impact of plasma volume status on the prognosis of acute heart failure syndromes. Methods and results: We analyzed 1115 patients with acute heart failure syndromes who were admitted to our hospital. These patients were divided into three groups based on their plasma volume status at admission: first tertile (plasma volume status <41.9%, n = 371), second tertile (41.9%⩽ plasma volume status <49.0%, n = 372), and third tertile (49.0%⩽ plasma volume status, n = 372). Plasma volume status was defined as follows: actual plasma volume = (1 − hematocrit) × [ a + ( b × body weight)] ( a=1530 in males and a=864 in females, b=41.0 in males and b=47.9 in females); ideal plasma volume = c × body weight ( c=39 in males and c=40 in females); and plasma volume status = [(actual plasma volume − ideal plasma volume)/ideal plasma volume] × 100 (%). In the Kaplan–Meier analysis, all-cause mortality, cardiac mortality and cardiac events increased progressively from the first to third tertile ( p <0.001, respectively). In the Cox proportional hazard analysis, after adjusting for potential confounding factors, plasma volume status was an independent predictor of all-cause mortality (hazard ratio 1.429, p < 0.001), cardiac mortality (hazard ratio 1.416, p = 0.001) and cardiac events (hazard ratio 1.207, p = 0.004). Conclusion: Increased congestion is associated with increased morbidity and mortality in heart failure patients. Plasma volume status, which represents intravascular compartment and congestion, can identify poor prognosis in patients with acute heart failure syndromes.

scholarly journals Correction to: Prognostic value of estimated plasma volume in acute heart failure in three cohort studies

2018 ◽  
Vol 108 (5) ◽  
pp. 562-562
Author(s):  
Masatake Kobayashi ◽  
Patrick Rossignol ◽  
João Pedro Ferreira ◽  
Irene Aragão ◽  
Yuki Paku ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cohort Studies ◽  
Acute Heart Failure ◽  
Plasma Volume ◽  
Prognostic Value

scholarly journals Effect of Estimated Plasma Volume Reduction on Renal Function for Acute Heart Failure Differs Between Patients With Preserved and Reduced Ejection Fraction

2015 ◽  
Vol 8 (3) ◽  
pp. 527-532 ◽  
Author(s):  
Makoto Takei ◽  
Shun Kohsaka ◽  
Yasuyuki Shiraishi ◽  
Ayumi Goda ◽  
Yuki Izumi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Renal Function ◽  
Ejection Fraction ◽  
Acute Heart Failure ◽  
Plasma Volume ◽  
Volume Reduction ◽  
Reduced Ejection Fraction

Effect of afterload reduction on plasma volume during acute heart failure

1978 ◽  
Vol 42 (5) ◽  
pp. 823-827 ◽  
Author(s):  
Robert J. Henning ◽  
Max Harry Weil
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Plasma Volume ◽  
Afterload Reduction

scholarly journals Strauss formula: a great and easy tool to manage congestion in acute heart failure

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A Martinho ◽  
J Almeida ◽  
G Campos ◽  
J Rosa ◽  
C Ferreira ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Plasma Volume ◽  
Clinical Laboratory ◽  
Cardiovascular Death ◽  
Positive Change ◽  
Gamma Glutamyl Transferase ◽  
Negative Change ◽  
Median Plasma ◽  
Glutamyl Transferase

Abstract Background Approaching the congestive patient is a complex task that requires the combination of different assessment methods. The Strauss formula uses variations in haemoglobin and haematocrit to estimate plasma volume variations (PVV) and haemoconcentration. However, this formula was only validated in outpatients followed with chronic heart failure. We aimed to assess the applicability of this formula to hospitalized patients for acute heart failure (AHF). Methods We conducted a single-centre, retrospective, observational study of 302 patients who were admitted to our hospital for AHF during 2016 and were discharged alive. Baseline clinical, laboratory and demographic characteristics were evaluated at admission and the Strauss formula was applied, as PVV (%) = 100 x [(Hb A / Hb D) x (1 − Hct D) / (1 − Hct A)] − 100), where A = admission and D = discharge. At discharge, we considered that a positive change (≥0%) in PV regarding the admission was linked to an increase in PV (haemodilution); a negative change (&lt;0%) correlated to a decrease in the PV (haemoconcentration). The primary endpoint was a composite of cardiovascular death (CV-death) and HF readmission at 3-months. Results Mean age was 76±11 years and 57% were male. At baseline, 92% were on clinical-haemodynamic profile B, with a median NT-proBNP of 2157 (IQR 1161–4242) pg/dL, a mean of glomerular filtration rate (GFR) of 63±57 mL/min/m2, a mean haemoglobin of 12±2 g/dL and a mean haematocrit of 38±6%. At discharge, the median plasma volume variation was −1.1% (IQR – 9.6 to 7.8) and the distribution of PVV values in the histogram reveals that a large proportion of patients (44%) increased or maintained plasma volume (PVV ≥0% – haemodilution). The group of patients who decreased plasma volume at discharge was slightly younger (75 vs 78 years, p=0.044), showing higher numerical decreases in NT-proBNP, gamma-glutamyl transferase (gGT) and bilirubin at discharge. A positive change in PV (PVV &gt;0%) during admission almost doubled the risk for readmission and CV-death at 3-months [OR 1.9 (95% CI: 1.1 to 3.1, p=0.026], after adjusting for age and sex. Conclusions In this work, we demonstrate that PVV, as calculated by the Strauss formula, increases or is unchanged in 44% of patients admitted with AHF and is strongly associated with a composite of 3-months CV death and HF readmission. Tools to guide the management of residual congestion are of great importance to assess the optimal discharge timing. Funding Acknowledgement Type of funding source: None

scholarly journals Prognostic Value of Both Plasma Volume Status and Nutritional Status in Patients With Severely Decompensated Acute Heart Failure

CJC Open ◽  
2019 ◽  
Vol 1 (6) ◽  
pp. 305-315
Author(s):  
Akihiro Shirakabe ◽  
Kuniya Asai ◽  
Nobuaki Kobayashi ◽  
Hirotake Okazaki ◽  
Masato Matsushita ◽  
...  
Keyword(s):  
Heart Failure ◽  
Nutritional Status ◽  
Acute Heart Failure ◽  
Plasma Volume ◽  
Prognostic Value ◽  
Volume Status

Prognostic value of estimated plasma volume in acute heart failure in three cohort studies

2018 ◽  
Vol 108 (5) ◽  
pp. 549-561 ◽  
Author(s):  
Masatake Kobayashi ◽  
Patrick Rossignol ◽  
João Pedro Ferreira ◽  
Irene Aragão ◽  
Yuki Paku ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cohort Studies ◽  
Acute Heart Failure ◽  
Plasma Volume ◽  
Prognostic Value

620 Modifications of left atrial reservoir function early after acute heart failure

1999 ◽  
Vol 1 ◽  
pp. S103-S103
Author(s):  
M ALIMENTO ◽  
P BARBIER ◽  
A GRIMALDI ◽  
G BERNA ◽  
M GUAZZI
Keyword(s):  
Heart Failure ◽  
Acute Heart Failure ◽  
Left Atrial ◽  
Reservoir Function
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