Investigating the individual importance of the Pam2Cys ester motifs on TLR2 activity

SummaryAccording to population-based studies, the prevalence of feelings of heaviness, swelling and pain in the legs is around 50 %. These feelings are often not accompanied by clinically detectable changes, but are the inevitable and generally unrecognised consequences of the increase in leg volume caused by standing still. We assume that the physiological change is detected as part of the constant information about the internal milieu that is sent to the corresponding centres in the brain. This information is modified by many factors, including emotion and – depending on the situation – is either appropriately perceived as an unpleasant sensation of swelling or not even noticed. These feelings can result in an impairment of vitality and depression. In some cases, a thorough phlebological work-up can reveal an occult organic venous disease, so that the feelings can be traced to a somatic cause. Feelings have a psychological and a somatic component; they are not imaginary. It is up to the doctor to discern the individual importance of the two components and to draw the appropriate conclusions regarding treatment.

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Digitainability: The Combined Effects of the Megatrends Digitalization and Sustainability

Journal of Innovation Management ◽

10.24840/2183-0606_009.002_0006 ◽

2021 ◽

Vol 9 (2) ◽

pp. 64-80

Author(s):

Ulrich Lichtenthaler

Keyword(s):

Cost Savings ◽

Digital Transformation ◽

Dark Side ◽

Strategic Initiatives ◽

New Business ◽

Sustainability Initiatives ◽

The Individual ◽

Fertilization Effects ◽

Individual Importance ◽

Cross Fertilization

The concept of digitainability has recently been suggested to underscore potential cross-fertilization effects between digitalization and sustainability, which have often been neglected. This article draws on an innovation-based view to develop a conceptual framework for combining digitalization and sustainability in firms’ strategic initiatives. It distinguishes four settings depending on whether firms pursue either digitalization or sustainability – or both or none of them to a strong degree. Beyond the individual importance of the two megatrends, their potential positive and negative interdependencies will gain further importance, and this article underscores the need for overcoming a potential dark side of digital solutions in terms of their carbon footprint and energy consumption to enable a sustainable digital transformation. In addition, digitainability offers the opportunity to move beyond optimization and cost savings due to digitalization and sustainability initiatives in order to capture the cross-fertilization potential of these two megatrends for innovation and new business development.

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Latent-Variable Approaches to the Jamesian Model of Importance-Weighted Averages

Personality and Social Psychology Bulletin ◽

10.1177/0146167212465321 ◽

2012 ◽

Vol 39 (1) ◽

pp. 100-114 ◽

Cited By ~ 10

Author(s):

L. Francesca Scalas ◽

Herbert W. Marsh ◽

Benjamin Nagengast ◽

Alexandre J. S. Morin

Keyword(s):

Latent Variable ◽

Empirical Support ◽

Weighted Average ◽

Self Esteem ◽

Self Concept ◽

Additional Information ◽

Multiple Item ◽

Spiritual Self ◽

The Individual ◽

Individual Importance

The individually importance-weighted average (IIWA) model posits that the contribution of specific areas of self-concept to global self-esteem varies systematically with the individual importance placed on each specific component. Although intuitively appealing, this model has weak empirical support; thus, within the framework of a substantive-methodological synergy, we propose a multiple-item latent approach to the IIWA model as applied to a range of self-concept domains (physical, academic, spiritual self-concepts) and subdomains (appearance, math, verbal self-concepts) in young adolescents from two countries. Tests considering simultaneously the effects of self-concept domains on trait self-esteem did not support the IIWA model. On the contrary, support for a normative group importance model was found, in which importance varied as a function of domains but not individuals. Individuals differentially weight the various components of self-concept; however, the weights are largely determined by normative processes, so that little additional information is gained from individual weightings.

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The willingness to donate blood: an empirical analysis of socio-demographic and motivation-related determinants

Health Services Management Research ◽

10.1258/0951484054572547 ◽

2005 ◽

Vol 18 (3) ◽

pp. 165-174 ◽

Cited By ~ 38

Author(s):

Dieter K Tscheulin ◽

Jörg Lindenmeier

Keyword(s):

Blood Donors ◽

Word Of Mouth ◽

Blood Donation ◽

Structural Characteristics ◽

Level Of Education ◽

Personal Involvement ◽

Willingness To Donate ◽

The Individual ◽

Individual Importance ◽

Very High

Since the willingness to donate blood is not very high among large parts of the population, a better understanding of the determinants for the willingness to donate blood is of significant importance. This article is intended to contribute to higher uniformity of results in the context of research on blood donation behaviour. Exploratory factor analysis and non-parametric tests are used to accomplish this. Potentially important socio-demographic and motivation-related variables particularly affecting the willingness to donate blood are examined. As an addition to the existing literature, the influence of the individual importance of structural characteristics of blood donation facilities, such as the standard of the facility's medical equipment or the training of the facility's staff, will be tested for its effects on the willingness to donate blood. The analysis will also include the influence of direct or indirect personal involvement on the part of the respondent. The results of the study indicate that typical blood donors are young women or men who are studying or possess a higher level of education. Furthermore, potential blood donors can easily be attracted by pecuniary incentives and word of mouth. Unlike non-donors, potential blood donors are not idle, have no fear of infections due to the donation and want reasonable opening hours of blood donation facilities.

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Who Determines What’s Important? Perceptions of Competence and Importance as Predictors of Self-Esteem in Youth Football Players

Pediatric Exercise Science ◽

10.1123/pes.5.3.253 ◽

1993 ◽

Vol 5 (3) ◽

pp. 253-262 ◽

Cited By ~ 9

Author(s):

Vicki Ebbeck ◽

Moira E. Stuart

Keyword(s):

Self Esteem ◽

Perceived Competence ◽

Predictor Variables ◽

Stepwise Multiple Regression ◽

Football Players ◽

Stepwise Multiple Regression Analysis ◽

Youth Football ◽

Competitive Season ◽

The Individual ◽

Individual Importance

The present study examined perceived competence, individual importance (what is important to the individual), and group importance (what is perceived to be important to the group) as determinants of self-esteem. The sample consisted of 100 male football players ranging in age from 11 to 14 years. A questionnaire containing items that assessed the central constructs was administered to the players during a team practice near the end of a 7-week competitive season. Self-esteem was the dependent variable, with perceived competence, individual importance, and group importance entered as the set of predictor variables in a non-stepwise multiple regression analysis. Results revealed that the set of predictor variables accounted for 47% of the variance in self-esteem. Both perceived competence and individual importance contributed significantly to explaining self-esteem, although perceived competence was the strongest predictor. The findings of this study are discussed in terms of how the values of significant others might influence the development of self-esteem.

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RELATIONSHIP AMONG DIFFERENT TESTS OF EVALUATING LOW BACK CORE STABILITY

Journal of Musculoskeletal Research ◽

10.1142/s0218957712500042 ◽

2011 ◽

Vol 14 (02) ◽

pp. 1250004 ◽

Cited By ~ 4

Author(s):

Anoop Aggarwal ◽

Suraj Kumar ◽

Ruchika Madan ◽

Ratnesh Kumar

Keyword(s):

Core Stability ◽

Low Back ◽

Single Test ◽

Core Stabilization ◽

The Core ◽

Stability Performance ◽

Different Types ◽

The Individual ◽

Individual Importance

Purpose: This study aims to determine the relation among the commonly used different tests of evaluating core stability performance. Establishing this relationship is important as different authors have used different types of tests for evaluating core stabilization in their study yet relation among these tests and the individual importance of each of these tests is not clearly established so far. Methods: Among 40 recreationally active subjects the core stability performance was evaluated using variety of different tests reported in the previous literatures. Results: Results show that there was no significant correlation among the performance scores on different test of core stability. Conclusions: The assessment of the core stability performance must be in concordance with the need of the individual and of the study. Also, different tasks or sports selectively require different components of the core stability. In order to evaluate more than one component of the core stability performance, the different combinations of the tests must be used. If one wishes to test all the components of the core stabilization, then no single test is sufficient and a battery of test must be used to assess different components separately.

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Jinnah and the Pakistan Demand

Modern Asian Studies ◽

10.1017/s0026749x00011069 ◽

1983 ◽

Vol 17 (4) ◽

pp. 529-561 ◽

Cited By ~ 10

Author(s):

R. J. Moore

Keyword(s):

Single Individual ◽

Eastern India ◽

Great Leader ◽

Muslim Majority ◽

The Individual ◽

Partition Of India ◽

The Voice ◽

Individual Importance ◽

North Western

In an age sceptical of the historic role of great men there is universal agreement that Mahomed Ali Jinnah was central to the Muslim League's emergence after 1937 as the voice of a Muslim nation; to its articulation in March 1940 of the Pakistan demand for separate statehood for the Muslim majority provinces of north-western and eastern India; and to its achievement in August 1947 of the separate but truncated state of Pakistan by the Partition of India. Subcontinental judgements of Jinnah are bound to be parti pris and to exaggerate his individual importance. While Pakistanis generally see him as the Quaid-i-Azam, Great Leader, or father of their nation, Indians often regard him as the Lucifer who tempted his people into the unforgivable sin against their nationalist faith. Among distinguished foreign scholars, unbiassed by national commitment, his stature is similarly elevated. Sir Penderel Moon has written:There is, I believe, no historical parallel for a single individual effecting such a political revolution; and his achievement is a striking refutation of the theory that in the making of history the individual is of little or no significance. It was Mr Jinnah who created Pakistan and undoubtedly made history.

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Narrative Conjuring or the Tales of Two Sisters? The Representations of Hannah and the Witch of Endor in 1 Samuel

Journal for the Study of the Old Testament ◽

10.1177/0309089216690382 ◽

2018 ◽

Vol 42 (4) ◽

pp. 469-489

Author(s):

Matthew MiChael

Keyword(s):

Narrative Space ◽

1 Samuel ◽

The Witch ◽

Intertextual Connections ◽

The Individual ◽

Individual Importance

The narrative of 1 Samuel opens graphically with the story of Hannah and also closes with the striking story of another woman, the ‘witch’ of Endor. These two women appear to occupy a significant place in the characterizations of 1 Samuel through the strategic locations of Hannah at the birth of Samuel, and the ‘witch’ at the death of Samuel. While past scholarship has described the individual importance of these two stories, the present study engages the intertextual connections between the two stories and the narrative importance of these two stories in the story world of 1 Samuel. Taking account of this intertextuality, the study underscores the hidden polemics inherent in their representations, especially in the staging of these two women in the same narrative space through the different literary echoes in the two stories that intertextually bind these women together as ‘literary sisters’ and mirrors of each other.

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