scholarly journals The impact of the stimulation method on differences in pain thresholds and brain responses between chronic pain patients and healthy controls

2014 ◽  
Vol 18 (10) ◽  
pp. 1365-1366
Author(s):  
Martin Diers
Keyword(s):  
Chronic Pain ◽  
Healthy Controls ◽  
Pain Thresholds ◽  
Brain Responses ◽  
Chronic Pain Patients ◽  
Stimulation Method ◽  
The Impact ◽  
Pain Patients

Electroencephalography During Nociceptive Stimulation in Chronic Pain Patients: A Systematic Review

Pain Medicine ◽  
2020 ◽  
Vol 21 (12) ◽  
pp. 3413-3427
Author(s):  
Dorine Lenoir ◽  
Ward Willaert ◽  
Iris Coppieters ◽  
Anneleen Malfliet ◽  
Kelly Ickmans ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chronic Pain ◽  
Neuropathic Pain ◽  
Subjective Experience ◽  
Event Related Potential ◽  
High Temporal Resolution ◽  
Healthy Controls ◽  
Somatosensory Processing ◽  
Chronic Pain Patients ◽  
Pain Patients

Abstract Background With its high temporal resolution, electroencephalography (EEG), a technique that records electrical activity of cortical neuronal cells, is a potentially suitable technique to investigate human somatosensory processing. By using EEG, the processing of (nociceptive) stimuli can be investigated, along with the functionality of the nociceptive pathway. Therefore, it can be applied in chronic pain patients to objectify whether changes have occurred in nociceptive processing. Typically, so-called event-related potential (ERP) recordings are used, where EEG signals are recorded in response to specific stimuli and characterized by latency and amplitude. Objective To summarize whether differences in somatosensory processing occur between chronic pain patients and healthy controls, measured with ERPs, and determine whether this response is related to the subjective pain intensity. Design Systematic review. Setting and Methods PubMed, Web of Science, and Embase were consulted, and 18 case–control studies were finally included. Subjects The chronic pain patients suffered from tension-type headache, back pain, migraine, fibromyalgia, carpal tunnel syndrome, prostatitis, or complex regional pain syndrome. Results Chronic neuropathic pain patients showed increased latencies of the N2 and P2 components, along with a decreased amplitude of the N2-P2 complex, which was also obtained in FM patients with small fiber dysfunction. The latter also showed a decreased amplitude of the N2-P3 and N1-P1 complex. For the other chronic pain patients, the latencies and the amplitudes of the ERP components did not seem to differ from healthy controls. One paper indicated that the N2-P3 peak-to-peak amplitude correlates with the subjective experience of the stimulus. Conclusions Differences in ERPs with healthy controls can mostly be found in chronic pain populations that suffer from neuropathic pain or where fiber dysfunction is present. In chronic pain populations with other etiological mechanisms, limited differences were found or agreed upon across studies.

The impact of opioid-induced constipation among chronic pain patients with sufficient laxative use

2015 ◽  
Vol 69 (12) ◽  
pp. 1448-1456 ◽  
Author(s):  
R. J. LoCasale ◽  
C. J. Datto ◽  
M. K. Margolis ◽  
J. Tack ◽  
K. S. Coyne
Keyword(s):  
Chronic Pain ◽  
Laxative Use ◽  
Chronic Pain Patients ◽  
The Impact ◽  
Pain Patients

The impact of structural therapy on functioning and pain in chronic pain patients: A pilot study1

2007 ◽  
Vol 20 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Alice V. Fann ◽  
H.J. Spencer ◽  
Amelia F. Hammaker ◽  
Svetlana Kligman ◽  
Richard P. Gray
Keyword(s):  
Chronic Pain ◽  
Chronic Pain Patients ◽  
Structural Therapy ◽  
The Impact ◽  
Pain Patients

scholarly journals Interactive Computer Method for Rating Quality of Life: Comparison of Chronic Pain Patients and Healthy Controls

Pain Medicine ◽  
2001 ◽  
Vol 2 (4) ◽  
pp. 298-308 ◽  
Author(s):  
Gilbert J. Faniciullo ◽  
Robert N. Jamison ◽  
Marek C. Chawarski ◽  
John C. Baird
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Computer Method ◽  
Healthy Controls ◽  
Chronic Pain Patients ◽  
Pain Patients

(337) 24-hour high-frequency heart rate variability in chronic pain patients compared to healthy controls – A meta-analysis

2015 ◽  
Vol 16 (4) ◽  
pp. S60
Author(s):  
J. Koenig ◽  
A. Bernardi ◽  
D. Williams ◽  
J. Thayer
Keyword(s):  
Heart Rate ◽  
Chronic Pain ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Meta Analysis ◽  
Healthy Controls ◽  
Chronic Pain Patients ◽  
Pain Patients

Neuropeptide FF-Like Immunoreactivity in Human Cerebrospinal Fluid of Chronic Pain Patients and Healthy Controls

Peptides ◽  
1997 ◽  
Vol 18 (7) ◽  
pp. 923-927 ◽  
Author(s):  
D.M Sundblom ◽  
E Kalso ◽  
I Tigerstedt ◽  
K Wahlbeck ◽  
P Panula ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Cerebrospinal Fluid ◽  
Healthy Controls ◽  
Human Cerebrospinal Fluid ◽  
Neuropeptide Ff ◽  
Chronic Pain Patients ◽  
Pain Patients

scholarly journals The Anxiety and Pain of Fibromyalgia Patients during the COVID-19 Pandemic

2020 ◽  
Author(s):  
A. Y. Kharko ◽  
K. J. Hansford ◽  
P. L. Furlong ◽  
S. D. Hall ◽  
M. E. Roser
Keyword(s):  
Chronic Pain ◽  
Online Survey ◽  
Mixed Effects ◽  
Caffeine Intake ◽  
Health Decline ◽  
Chronic Pain Patients ◽  
The Impact ◽  
Pain Patients ◽  
Mild Analgesics

AbstractBackgroundEarly research on the impact of the COVID-19 pandemic found persistent related anxiety in the general population. We hypothesised that this anxiety will be associated with increased pain in chronic pain patients diagnosed with fibromyalgia (FM).MethodsTo study this, we carried out a 10-day online survey with 58 female participants, diagnosed with FM and no other pain condition. We identified which aspects of the COVID-19 pandemic evoked anxiety. We then asked participants to provide daily ratings of both anxiety and pain on 101-point visual analogue scales (VAS). Key participant characteristics were included as mediators in a mixed-effects analysis, where the primary outcome was pain VAS.ResultsWe found that participants were most often anxious about “impact on relationships”, “a family member contracting COVID-19”, and “financial hardships”, but on average rated “financial hardship”, “access to medication”, and “home loss/eviction” as evoking the strongest anxiety. Mixed-effects modelling showed that an increase in pain was significantly associated with an increase in anxiety, when taking into account individual variance and daily caffeine intake. Age and intake of some mild analgesics were also linked to stronger pain.ConclusionOur results extend the initial findings from the literature about the effects of COVID-19 pandemic on chronic pain sufferers. We found that not only is pandemic anxiety in FM patients present, but it is associated with amplified self-assessed chronic pain.SignificanceThe long-term support of fibromyalgia patients is challenging for healthcare professionals due to the nature of the condition. The new normal introduced by the pandemic particularly hinders pain management, which is the leading request from this patient group. Our study demonstrates that mental health decline during the COVID-19 pandemic is directly related to the worsening of pain in fibromyalgia. Core stressors that evoke the strongest anxiety were identified thus providing guidance for where to focus patient support.

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