Enantiomeric separation of chiral dipeptides by CE-ESI-MS employing a partial filling technique with chiral crown ether

2009 ◽  
Vol 30 (16) ◽  
pp. 2837-2844 ◽  
Author(s):  
Shifei Xia ◽  
Lan Zhang ◽  
Minghua Lu ◽  
Bin Qiu ◽  
Yuwu Chi ◽  
...  
Keyword(s):  
Crown Ether ◽  
Enantiomeric Separation ◽  
Chiral Crown Ether ◽  
Esi Ms ◽  
Partial Filling ◽  
Partial Filling Technique

scholarly journals USING OPTICALLY ACTIVE CHIRAL CROWN ETHER AT ENANTIOMERIC SEPARATION OF AMINES

2021 ◽  
pp. 59-62
Author(s):  
U.A. Hasanova ◽  
◽  
Z.O. Qahramanova ◽  
P.F. Huseynova ◽  
◽  
...  
Keyword(s):  
Crown Ether ◽  
Optical Activity ◽  
Column Chromatography ◽  
Chromatographic Separation ◽  
Enantiomeric Separation ◽  
Optically Active ◽  
Racemic Mixture ◽  
Chiral Crown Ether ◽  
Physicochemical Methods ◽  
Formation Of Complexes

The synthesized S-enantiomer of the crown ether was used as an adsorbent to separate the racemic mixture of L-alanine ether of phenamine into individual diastereomers by column chromatography. Chromatographic separation occurred due to the formation of complexes of different stability between diastereomers and optically selective adsorbents on a host-guest principle. The separated diastereomers were converted into enantiomers by hydrolysis. The structure and optical activity of the synthesized crown ether and separated enantiomers were investigated by physicochemical methods

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