scholarly journals Back Cover: A new single-urea-bound 3,5-dimethylphenylcarbamoylated β-cyclodextrin chiral stationary phase and its enhanced separation performance in normal-phase liquid chromatography

2018 ◽  
Vol 39 (2) ◽  
pp. NA-NA
Author(s):  
Chun Lin ◽  
Jun Fan ◽  
Wenna Liu ◽  
Xiaodong Chen ◽  
Lijun Ruan ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Stationary Phase ◽  
Chiral Stationary Phase ◽  
Normal Phase ◽  
Separation Performance ◽  
Back Cover ◽  
Phase Liquid

Chiral separation and a molecular modeling study of eight azole antifungals on the cellulose tris(3,5-dichlorophenylcarbamate) chiral stationary phase

2018 ◽  
Vol 42 (16) ◽  
pp. 13421-13429 ◽  
Author(s):  
Bolin Zhu ◽  
Fan Zhao ◽  
Jia Yu ◽  
Zhaokun Wang ◽  
Yongbo Song ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Molecular Modeling ◽  
Stationary Phase ◽  
Chiral Separation ◽  
Chiral Stationary Phase ◽  
Stationary Phases ◽  
Chiral Stationary Phases ◽  
Normal Phase ◽  
Azole Antifungals ◽  
Phase Liquid

Four immobilized polysaccharide-based chiral stationary phases have been examined for their enantioselectivity on azole analytes using normal phase liquid chromatography.

Chiral Separation of 3,4-dihydropyrimidin-2(1H)-ones and 3,4-di -hydropyrimidin- 2(1H)-thiones Enantiomers by HPLC on Chiralcel®OD-H

2020 ◽  
Vol 16 (3) ◽  
pp. 250-255
Author(s):  
Noura Kichou ◽  
Ismahan Rahou ◽  
Zaid M. Elamin ◽  
Khaled Sekkoum ◽  
Nasser Belboukhari ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Stationary Phase ◽  
Chiral Separation ◽  
Chiral Stationary Phase ◽  
Normal Phase ◽  
Good Resolution ◽  
Mode Structure ◽  
Structure Retention ◽  
Short Time

Objective: Ten racemic 3,4-dihydropyrimidin-2(1H)-ones and 3,4-dihydropyrimidin- 2(1H)-thiones were separated by liquid chromatography on Chiralcel®OD-H column containing cellulose tris(3, 5-dimethylphenylcarbamate). Methods: The enantioseparation was carried out using Chiralcel®OD-H polysaccharide-type chiral stationary phase to resolve such enantiomers under normal-phase mode. Results: Complete separations of the 3,4-dihydropyrimidin-2(1H)-ones and 3,4-dihydropyrimidin- 2(1H)-thiones derivatives with good resolution (RS= 1.04-2.80) were achieved within a short time (10-15 min). Conclusion: An optimal baseline separation (Rs> 1.5) was achieved using Chiralcel®OD-H under normal-phase mode. Structure-retention relationships have also been discussed.

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