scholarly journals Impaired swim bladder inflation in early life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid

2017 ◽  
Vol 36 (11) ◽  
pp. 2942-2952 ◽  
Author(s):  
Jenna E. Cavallin ◽  
Gerald T. Ankley ◽  
Brett R. Blackwell ◽  
Chad A. Blanksma ◽  
Kellie A. Fay ◽  
...  
Keyword(s):  
Early Life ◽  
Life Stage ◽  
Early Life Stage ◽  
Fathead Minnows ◽  
Swim Bladder ◽  
Iopanoic Acid ◽  
Swim Bladder Inflation

Early life-stage toxicity in zebrafish (Danio rerio) following embryonal exposure to selected polychlorinated biphenyls

2007 ◽  
Vol 23 (9) ◽  
pp. 529-536 ◽  
Author(s):  
T Şişman ◽  
F Geyikoğlu ◽  
M Atamanalp
Keyword(s):  
Polychlorinated Biphenyls ◽  
Danio Rerio ◽  
Early Life ◽  
Polychlorinated Biphenyl ◽  
Larval Mortality ◽  
Life Stage ◽  
Early Life Stage ◽  
Receptor Activation ◽  
Swim Bladder ◽  
Swim Bladder Inflation

Polychlorinated biphenyls are a widespread aquatic contaminant. In this article, specific polychlorinated biphenyl congeners were examined for embryo and early life-stage toxicity in zebrafish ( Danio rerio). A set of three polychlorinated biphenyl congeners (non-ortho polychlorinated biphenyl 126, mono-ortho polychlorinated biphenyl 28 and di-ortho polychlorinated biphenyl 153) were tested. The typical lesions observed were yolk sac edema, vertebra defect, craniofacial malformations (double head, triple retina), anaxial body and inhibition of swim bladder inflation. Moreover, embryo and larval mortality increased and hatching success decreased. The severity of abnormalities and mortalities were concentration- and congener-dependent. Of the compounds tested, polychlorinated biphenyl congener 126 was found to be highly toxic to the fish embryos following exposure. The Lethal Concentration 50 values for polychlorinated biphenyl 28, polychlorinated biphenyl 126, polychlorinated biphenyl 153 calculated by probit analysis were 3.270, 1.298 and 5.375 ppm, respectively. The inhibition of swim bladder inflation was the most sensitive endpoint measured, and it is suggested that the inhibition of swim bladder inflation may be mediated by mechanism with an aryl hydrocarbon receptor activation.

Early life-stage and multigeneration toxicity study with bisphenol A and fathead minnows (Pimephales promelas)

2011 ◽  
Vol 74 (6) ◽  
pp. 1548-1557 ◽  
Author(s):  
Charles A. Staples ◽  
A. Tilghman Hall ◽  
Urs Friederich ◽  
Norbert Caspers ◽  
Gary M. Klecka
Keyword(s):  
Bisphenol A ◽  
Early Life ◽  
Life Stage ◽  
Pimephales Promelas ◽  
Early Life Stage ◽  
Toxicity Study ◽  
Fathead Minnows

Evaluation of whole-mount in situ hybridization as a tool for pathway-based toxicological research with early-life stage fathead minnows

2015 ◽  
Vol 169 ◽  
pp. 19-26 ◽  
Author(s):  
J.E. Cavallin ◽  
A.L. Schroeder ◽  
K.M. Jensen ◽  
D.L. Villeneuve ◽  
B.R. Blackwell ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Early Life ◽  
Life Stage ◽  
Early Life Stage ◽  
Fathead Minnows ◽  
Whole Mount ◽  
Toxicological Research

Development of a Comprehensive Toxicity Pathway Model for 17α-Ethinylestradiol in Early Life Stage Fathead Minnows (Pimephales promelas)

2021 ◽  
Vol 55 (8) ◽  
pp. 5024-5036
Author(s):  
Alper James G. Alcaraz ◽  
David Potěšil ◽  
Kamil Mikulášek ◽  
Derek Green ◽  
Bradley Park ◽  
...  
Keyword(s):  
Early Life ◽  
Life Stage ◽  
Pimephales Promelas ◽  
Early Life Stage ◽  
Fathead Minnows ◽  
Pathway Model ◽  
Toxicity Pathway

Toxicity of 3,4-dichloroaniline to fathead minnows,Pimephales promelas, in acute and early life-stage exposures

1987 ◽  
Vol 38 (2) ◽  
pp. 352-358 ◽  
Author(s):  
D. J. Call ◽  
S. H. Poirier ◽  
M. L. Knuth ◽  
S. L. Harting ◽  
C. A. Lindberg
Keyword(s):  
Early Life ◽  
Life Stage ◽  
Pimephales Promelas ◽  
Early Life Stage ◽  
Fathead Minnows
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