Isolated pericardial metastasis of parotid tumor origin

1982 ◽  
Vol 4 (4) ◽  
pp. 344-348 ◽  
Author(s):  
Aaron Sulkes ◽  
Zeev Weshler ◽  
Leah Dolberg ◽  
Shoshana Biran
ORL ◽  
2021 ◽  
pp. 1-10
Author(s):  
Claudia Scherl ◽  
Johanna Stratemeier ◽  
Nicole Rotter ◽  
Jürgen Hesser ◽  
Stefan O. Schönberg ◽  
...  

<b><i>Introduction:</i></b> Augmented reality can improve planning and execution of surgical procedures. Head-mounted devices such as the HoloLens® (Microsoft, Redmond, WA, USA) are particularly suitable to achieve these aims because they are controlled by hand gestures and enable contactless handling in a sterile environment. <b><i>Objectives:</i></b> So far, these systems have not yet found their way into the operating room for surgery of the parotid gland. This study explored the feasibility and accuracy of augmented reality-assisted parotid surgery. <b><i>Methods:</i></b> 2D MRI holographic images were created, and 3D holograms were reconstructed from MRI DICOM files and made visible via the HoloLens. 2D MRI slices were scrolled through, 3D images were rotated, and 3D structures were shown and hidden only using hand gestures. The 3D model and the patient were aligned manually. <b><i>Results:</i></b> The use of augmented reality with the HoloLens in parotic surgery was feasible. Gestures were recognized correctly. Mean accuracy of superimposition of the holographic model and patient’s anatomy was 1.3 cm. Highly significant differences were seen in position error of registration between central and peripheral structures (<i>p</i> = 0.0059), with a least deviation of 10.9 mm (centrally) and highest deviation for the peripheral parts (19.6-mm deviation). <b><i>Conclusion:</i></b> This pilot study offers a first proof of concept of the clinical feasibility of the HoloLens for parotid tumor surgery. Workflow is not affected, but additional information is provided. The surgical performance could become safer through the navigation-like application of reality-fused 3D holograms, and it improves ergonomics without compromising sterility. Superimposition of the 3D holograms with the surgical field was possible, but further invention is necessary to improve the accuracy.


2021 ◽  
Vol 22 (15) ◽  
pp. 7872
Author(s):  
Malin Tordis Meyer ◽  
Christoph Watermann ◽  
Thomas Dreyer ◽  
Steffen Wagner ◽  
Claus Wittekindt ◽  
...  

Salivary gland cancers are rare but aggressive tumors that have poor prognosis and lack effective cure. Of those, parotid tumors constitute the majority. Functioning as metabolic machinery contributing to cellular redox balance, peroxisomes have emerged as crucial players in tumorigenesis. Studies on murine and human cells have examined the role of peroxisomes in carcinogenesis with conflicting results. These studies either examined the consequences of altered peroxisomal proliferators or compared their expression in healthy and neoplastic tissues. None, however, examined such differences exclusively in human parotid tissue or extended comparison to peroxisomal proteins and their associated gene expressions. Therefore, we examined differences in peroxisomal dynamics in parotid tumors of different morphologies. Using immunofluorescence and quantitative PCR, we compared the expression levels of key peroxisomal enzymes and proliferators in healthy and neoplastic parotid tissue samples. Three parotid tumor subtypes were examined: pleomorphic adenoma, mucoepidermoid carcinoma and acinic cell carcinoma. We observed higher expression of peroxisomal matrix proteins in neoplastic samples with exceptional down regulation of certain enzymes; however, the degree of expression varied between tumor subtypes. Our findings confirm previous experimental results on other organ tissues and suggest peroxisomes as possible therapeutic targets or markers in all or certain subtypes of parotid neoplasms.


2003 ◽  
Vol 96 (12) ◽  
pp. 1095-1098 ◽  
Author(s):  
Ryoji Ishida ◽  
Hiroyuki Yamada ◽  
Sin-ichiro Nishii

Life ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 638
Author(s):  
Linjing Liu ◽  
Xingjian Chen ◽  
Olutomilayo Olayemi Petinrin ◽  
Weitong Zhang ◽  
Saifur Rahaman ◽  
...  

With the advances of liquid biopsy technology, there is increasing evidence that body fluid such as blood, urine, and saliva could harbor the potential biomarkers associated with tumor origin. Traditional correlation analysis methods are no longer sufficient to capture the high-resolution complex relationships between biomarkers and cancer subtype heterogeneity. To address the challenge, researchers proposed machine learning techniques with liquid biopsy data to explore the essence of tumor origin together. In this survey, we review the machine learning protocols and provide corresponding code demos for the approaches mentioned. We discuss algorithmic principles and frameworks extensively developed to reveal cancer mechanisms and consider the future prospects in biomarker exploration and cancer diagnostics.


2010 ◽  
Vol 2 (1) ◽  
pp. 6
Author(s):  
Hassan Mohamed Al Bisher

Coexistence of parotid tuberculosis along with a benign parotid tumor is a rare entity with only nine cases reported in the literature. We report here a case of primary parotid tuberculosis with concurrent pleomorphic adenoma in a 51-year-old female.


2008 ◽  
Vol 18 (3) ◽  
pp. 251-257
Author(s):  
Suetaka Nishiike ◽  
Dai Shibata ◽  
Masako Uno ◽  
Hidenori Inohara
Keyword(s):  

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