scholarly journals Paracrine regulation of glioma cells invasion by astrocytes is mediated by glial-derived neurotrophic factor

2014 ◽  
Vol 137 (5) ◽  
pp. 1012-1020 ◽  
Author(s):  
Ayelet Shabtay-Orbach ◽  
Moran Amit ◽  
Yoav Binenbaum ◽  
Shorook Na'ara ◽  
Ziv Gil
2012 ◽  
Vol 136 ◽  
pp. S132-S133
Author(s):  
Anna Leszczynska-Rodziewicz ◽  
Maria Skibinska ◽  
Pawel Kapelski ◽  
Aleksandra Rajewska-Rager ◽  
Joanna Pawlak ◽  
...  

2021 ◽  
Vol 22 (5) ◽  
pp. 2521
Author(s):  
Kinga K. Borowicz-Reutt

Depression coexists with epilepsy, worsening its course. Treatment of the two diseases enables the possibility of interactions between antidepressant and antiepileptic drugs. The aim of this review was to analyze such interactions in one animal seizure model—the maximal electroshock (MES) in mice. Although numerous antidepressants showed an anticonvulsant action, mianserin exhibited a proconvulsant effect against electroconvulsions. In most cases, antidepressants potentiated or remained ineffective in relation to the antielectroshock action of classical antiepileptic drugs. However, mianserin and trazodone reduced the action of valproate, phenytoin, and carbamazepine against the MES test. Antiseizure drug effects were potentiated by all groups of antidepressants independently of their mechanisms of action. Therefore, other factors, including brain-derived neurotrophic factor (BDNF) and glial-derived neurotrophic factor (GDNF) modulation, should be considered as the background for the effect of drug combinations.


1998 ◽  
Vol 12 (4-5) ◽  
pp. 256-268 ◽  
Author(s):  
Elizabeth J. Bradbury ◽  
Geoffery Burnstock ◽  
Stephen B. McMahon

2011 ◽  
Vol 39 (7) ◽  
pp. 1149-1154 ◽  
Author(s):  
Qing-Hui Zhou ◽  
Ruben J. Boado ◽  
Eric Ka-Wai Hui ◽  
Jeff Zhiqiang Lu ◽  
William M. Pardridge

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