Colorectal cancer survival in sub‐Saharan Africa by age, stage at diagnosis, and Human Development Index: A population‐based registry study

Author(s):  
Cricket Gullickson ◽  
Michael Goodman ◽  
Yvonne W. Joko‐Fru ◽  
Freddy Houéhanou Rodrigue Gnangnon ◽  
Guy N'Da ◽  
...  

2020 ◽  
Vol 147 (11) ◽  
pp. 3037-3048 ◽  
Author(s):  
Mazvita Sengayi‐Muchengeti ◽  
Walburga Yvonne Joko‐Fru ◽  
Adalberto Miranda‐Filho ◽  
Marcel Egue ◽  
Marie‐Therese Akele‐Akpo ◽  
...  


2019 ◽  
Vol 146 (5) ◽  
pp. 1208-1218 ◽  
Author(s):  
Walburga Y. Joko‐Fru ◽  
Adalberto Miranda‐Filho ◽  
Isabelle Soerjomataram ◽  
Marcel Egue ◽  
Marie‐Therese Akele‐Akpo ◽  
...  


Author(s):  
Tobias P. Seraphin ◽  
Walburga Y. Joko-Fru ◽  
Shyam S. Manraj ◽  
Eric Chokunonga ◽  
Nontuthuzelo I. M. Somdyala ◽  
...  

Abstract Objectives To estimate observed and relative survival of prostate cancer patients in sub-Saharan Africa (SSA) and to examine the influence of age, stage at diagnosis and the Human Development Index (HDI). Patients and methods In this comparative registry study, we selected a random sample of 1752 incident cases of malign prostatic neoplasm from 12 population-based cancer registries from 10 SSA countries, registered between 2005 and 2015. We analyzed the data using Kaplan-Meier and Ederer II methods to obtain outcome estimates and flexible Poisson regression modeling to calculate the excess hazards of death Results For the 1406 patients included in the survival analyses, 763 deaths occurred during 3614 person-years of observation. Of patients with known stage, 45.2% had stage IV disease, 31.2% stage III and only 23.6% stage I and II. The 1 and 5-year relative survival for the entire cohort was 78.0% (75.4–80.7) and 60.0% (55.7–64.6), while varying between the registries. Late presentation was associated with increased excess hazards and a 0.1 increase in the HDI was associated with a 20% lower excess hazard of death, while for age at diagnosis no association was found. Conclusions We found poor survival of SSA prostatic tumor patients, as well as high proportions of late stage presentation, which are associated with inferior outcome. This calls for investment in health-care systems and action regarding projects to raise awareness among the population to achieve earlier diagnosis and improve survival.



Cancer ◽  
2021 ◽  
Author(s):  
Tobias Paul Seraphin ◽  
Walburga Yvonne Joko‐Fru ◽  
Lucia Hämmerl ◽  
Mirko Griesel ◽  
Nikolaus Christian Simon Mezger ◽  
...  


2007 ◽  
Vol 136 (5) ◽  
pp. 577-603 ◽  
Author(s):  
P. K. RAM ◽  
J. A. CRUMP ◽  
S. K. GUPTA ◽  
M. A. MILLER ◽  
E. D. MINTZ

SUMMARYThe global incidence ofShigellainfection has been estimated at 80–165 million episodes annually, with 99% of episodes occurring in the developing world. To identify contemporary gaps in the understanding of the global epidemiology of shigellosis, we conducted a review of the English-language scientific literature from 1984 to 2005, restricting the search to low and medium human development countries. Our review yielded 11 population-based studies ofShigellaburden from seven countries. No population-based studies have been conducted in sub-Saharan Africa or in low human development countries. In studies done in all age groups,Shigellaincidence varied from 0·6 to 107 episodes/1000 person-years.S. flexneriwas the most commonly detected subgroup in the majority of studies. Case-fatality rates ranged from 0% to 2·6% in population-based studies and from 0% to 21% in facility-based studies. This review highlights the large gaps in data on the burden ofShigellainfections for low human development index countries and, more specifically, for sub-Saharan Africa.



Author(s):  
Partha Dasgupta

In this paper, I formalize the idea of sustainable development in terms of intergenerational well-being. I then sketch an argument that has recently been put forward formally to demonstrate that intergenerational well-being increases over time if and only if a comprehensive measure of wealth per capita increases. The measure of wealth includes not only manufactured capital, knowledge and human capital (education and health), but also natural capital (e.g. ecosystems). I show that a country's comprehensive wealth per capita can decline even while gross domestic product (GDP) per capita increases and the UN Human Development Index records an improvement. I then use some rough and ready data from the world's poorest countries and regions to show that during the period 1970–2000 wealth per capita declined in South Asia and sub-Saharan Africa, even though the Human Development Index (HDI) showed an improvement everywhere and GDP per capita increased in all places (except in sub-Saharan Africa, where there was a slight decline). I conclude that, as none of the development indicators currently in use is able to reveal whether development has been, or is expected to be, sustainable, national statistical offices and international organizations should now routinely estimate the (comprehensive) wealth of nations.



2020 ◽  
Author(s):  
Sai San Moon Lu ◽  
Zahraa Mohammed ◽  
Christel Häggström ◽  
Robin Myte ◽  
Elisabeth Lindquist ◽  
...  


2013 ◽  
Vol 52 (5) ◽  
pp. 919-932 ◽  
Author(s):  
Camille Maringe ◽  
Sarah Walters ◽  
Bernard Rachet ◽  
John Butler ◽  
Tony Fields ◽  
...  


2021 ◽  
pp. 121-134
Author(s):  
Anna Kachanova

The paper discusses possible ways to overcome one of the most relevant global problems – poverty in the developing countries. The study is based on a component analysis of the Human Development Index as a quantitative indicator of living standards for the three poorest countries in Sub–Saharan Africa – Burkina Faso, Ghana and Cote d’Ivoire – with close economic, geographical and diplomatic ties. The standard of living in each of the three countries and its dependence on four groups of the most important factors (export and import levels, net current transfers from abroad, grants from the International Development Association etc.) are analyzed. The human development index is used in the study as an indicator that most fully reflects the actual situation in the state in terms of living conditions of the population and opportunities for development available to them. The analysis carried out in the article made it possible to reveal the strength and direction of the relationship between the standard of living in each of the countries (HDI) and the factors identified earlier. Particular interest in the article is given to the description and interpretation of the results, which at first glance seem paradoxical and impossible, but upon a more detailed examination acquire a certain meaning and high significance. Recommendations are given to improve the situation in each of the listed countries, taking into account their economic and social characteristics, problems and prospects. Particular attention is paid to identifying individual strategies that will allow each of the countries to qualitatively increase the standard of living of the population and will help accelerate the development of the national economy.





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