Measurement errors related to contact angle analysis of hydrogel and silicone hydrogel contact lenses

In this study, silicone-based hydrogel contact lenses were prepared by the polymerization of 3-(methacryloyloxy)propyltris(trimethylsiloxy)silane (TRIS), N,N-dimethylacrylamide (DMA), 1-vinyl-2-pyrrolidinone (NVP), and 2-hydroxyethylmethacrylate (HEMA). The properties of silicone hydrogel lenses were analyzed based on the methods such as equilibrium water content, oxygen permeability, optical transparency, contact angle, mechanical test, protein adsorption, and cell toxicity. The results showed that the TRIS content in all formulations increased the oxygen permeability and decreased the equilibrium water content, while both DMA and NVP contributed the hydrophilicity of the hydrogels. The maximum value of oxygen permeability was 74.9 barrers, corresponding to an equilibrium water content of 44.5% as well as a contact angle of 82°. Moreover, L929 fibroblasts grew on all these hydrogels, suggesting non-cytotoxicity. In general, the silicone hydrogels in this work exhibited good oxygen permeability, stiffness, and optical transparency as well as anti-protein adsorption. Hence, these silicone hydrogel polymers would be feasible for making contact lens.

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The Influence of Structure and Morphology on Ion Permeation Behaviour in Commercial Silicone Hydrogel Contact Lenses

SSRN Electronic Journal ◽

10.2139/ssrn.3458141 ◽

2019 ◽

Author(s):

Virginia Saez-Martinez ◽

Aisling Mann ◽

Fiona Lydon ◽

Frank Molock ◽

Siân A. Layton ◽

...

Keyword(s):

Contact Lenses ◽

Ion Permeation ◽

Silicone Hydrogel ◽

Structure And Morphology

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Modification of therapeutic silicone-hydrogel soft contact lenses

Clinical ophthalmology ◽

10.21689/2311-7729-2016-16-3-117-120 ◽

2016 ◽

Vol 16 (3) ◽

pp. 117-120 ◽

Cited By ~ 1

Author(s):

T.N. Safonova ◽

◽

I.A. Novikov ◽

V.I. Boev ◽

O.V. Gladkova ◽

...

Keyword(s):

Contact Lenses ◽

Soft Contact ◽

Silicone Hydrogel ◽

Soft Contact Lenses

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Antifouling and Flux Enhancement of Reverse Osmosis Membrane by Grafting Poly (3-Sulfopropyl Methacrylate) Brushes

Membranes ◽

10.3390/membranes11030213 ◽

2021 ◽

Vol 11 (3) ◽

pp. 213

Author(s):

Reema Mushtaq ◽

Muhammad Asad Abbas ◽

Shehla Mushtaq ◽

Nasir M. Ahmad ◽

Niaz Ali Khan ◽

...

Keyword(s):

Contact Angle ◽

Reverse Osmosis ◽

Polymer Brushes ◽

Surface Composition ◽

Reverse Osmosis Membrane ◽

Optical Profilometry ◽

Thin Film Composite ◽

Membrane Sample ◽

Contact Angle Analysis ◽

And Staphylococcus Aureus

A commercial thin film composite (TFC) polyamide (PA) reverse osmosis membrane was grafted with 3-sulfopropyl methacrylate potassium (SPMK) to produce PA-g-SPMK by atom transfer radical polymerization (ATRP). The grafting of PA was done at varied concentrations of SPMK, and its effect on the surface composition and morphology was studied by Fourier-Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), optical profilometry, and contact angle analysis. The grafting of hydrophilic ionically charged PSPMK polymer brushes having acrylate and sulfonate groups resulted in enhanced hydrophilicity rendering a reduction of contact angle from 58° of pristine membrane sample labeled as MH0 to 10° for a modified membrane sample labeled as MH3. Due to the increased hydrophilicity, the flux rate rises from 57.1 L m−2 h−1 to 71.2 L m−2 h−1, and 99% resistance against microbial adhesion (Escherichia coli and Staphylococcus aureus) was obtained for MH3 after modification

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