Responsibility, thought-action fusion, and thought suppression in Turkish patients with obsessive–compulsive disorder

2008 ◽  
Vol 64 (3) ◽  
pp. 308-317 ◽  
Author(s):  
O. Yorulmaz ◽  
A.N Karanci ◽  
B. Bastug ◽  
C. Kisa ◽  
E. Goka
2001 ◽  
Vol 39 (7) ◽  
pp. 757-764 ◽  
Author(s):  
Eric Rassin ◽  
Philip Diepstraten ◽  
Harald Merckelbach ◽  
Peter Muris

2003 ◽  
Vol 18 (5) ◽  
pp. 249-254 ◽  
Author(s):  
Şenel Tot ◽  
M. Emin Erdal ◽  
Kemal Yazıcı ◽  
Aylin Ertekin Yazıcı ◽  
Özmen Metin

AbstractObjectiveThis study aimed to investigate the possible association between T102C and –1438 G/A polymorphism in the 5-HT2A receptor gene and susceptibility to and clinical features of obsessive–compulsive disorder (OCD).MethodFifty-eight patients with OCD and 83 healthy controls were included in the study. All patients were interviewed and rated by Yale-Brown Obsessive–Compulsive Scale. T102C and –1438 G/A polymorphisms of 5-HT2A receptor gene were determined by PCR technique in DNAs of peripheral leucocytes.ResultsOCD patients and healthy controls did not show significant differences in genotype distribution for both polymorphisms investigated. We found that frequencies of the TT genotype for T102C polymorphism and the AA genotype for –1438 G/A polymorphism were significantly higher in patients with severe OCD compared to those with moderate or moderate–severe OCD.ConclusionThe –1438 G/A and T102C polymorphisms of the 5-HT2A receptor gene are not associated with an increased risk of OCD. Our data suggest that the TT genotype of T102C and the AA genotype of –1438 G/A polymorphism might be a factor in clinical severity of OCD.


1996 ◽  
Vol 10 (5) ◽  
pp. 379-391 ◽  
Author(s):  
Roz Shafran ◽  
Dana S. Thordarson ◽  
S. Rachman

2007 ◽  
Vol 24 (3) ◽  
pp. 146-156 ◽  
Author(s):  
Müjgan Altın ◽  
Tülin Gençöz

AbstractContemporary cognitive theories of obsessive-compulsive disorder (OCD) propose that certain types of dysfunctional beliefs and assumptions play a salient role in the genesis and persistence of OCD (e.g., Clark, 2004; Rachman, 1993, 1997; Salkovskis, 1985). The present study aimed to examine whether the three proposed dysfunctional beliefs — inflated sense of responsibility, thought suppression, and thought-action fusion — play a significant role particularly on the persistence of obsessive–compulsive (OC) symptoms, as compared to other emotional disorders, such as symptoms of depression. The participants of the present study were 109 undergraduate university students, who completed a set of questionnaires, including The Responsibility Attitude Scale (RAS), The Thought Action Fusion Scale (TAF), The White Bear Suppression Inventory (WBSI), The Maudsley Obsessive–Compulsive Inventory (MOCI), and The Beck Depression Inventory (BDI). After a 4-week interval, participants were again asked to complete the MOCI and BDI. Two separate hierarchical regression equations were formulated to examine the factors significantly accounting for the residual changes from Time 1 to Time 2 assessments of OC and depressive symptomatologies. Results of these analyses indicated that while thought suppression (WBSI scores) played a significant role on the persistence of both OC and depressive symptoms across time, the role of inflated sense of responsibility (RAS scores) was specific to the persistence of OC symptoms.


Sign in / Sign up

Export Citation Format

Share Document