Therapeutic Protein Drug Interaction Potential in Subjects With Psoriasis: An Assessment Based on Population Pharmacokinetic Analyses of Sensitive Cytochrome P450 Probe Substrates

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1744 ◽

2020 ◽

Author(s):

Abhishek G. Sathe ◽

Ahmed A. Othman ◽

Mohamed‐Eslam F. Mohamed

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Interaction Potential ◽

Therapeutic Protein ◽

Population Pharmacokinetic ◽

Protein Drug

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Herb–drug interaction potential of Berberis aristata through cytochrome P450 inhibition assay

Synergy ◽

10.1016/j.synres.2016.12.001 ◽

2017 ◽

Vol 4 ◽

pp. 1-7 ◽

Cited By ~ 3

Author(s):

Shiv Bahadur ◽

Pulok K. Mukherjee ◽

Subrata Pandit ◽

S.K. Milan Ahmmed ◽

Amit Kar

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Interaction Potential ◽

Inhibition Assay

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Use of Multiple Probes to Assess Transporter- and Cytochrome P450-Mediated Drug–Drug Interaction Potential of the Pangenotypic HCV NS5A Inhibitor Velpatasvir

Clinical Pharmacokinetics ◽

10.1007/s40262-015-0334-7 ◽

2015 ◽

Vol 55 (5) ◽

pp. 605-613 ◽

Cited By ~ 32

Author(s):

Erik Mogalian ◽

Polina German ◽

Brian P. Kearney ◽

Cheng Yong Yang ◽

Diana Brainard ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Interaction Potential ◽

Ns5a Inhibitor ◽

Drug Drug Interaction

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P533. Assessment of disease-related therapeutic protein drug-drug interaction (TP-DDI) for etrolizumab in patients with moderately to severely active ulcerative colitis (UC)

Journal of Crohn s and Colitis ◽

10.1093/ecco-jcc/jju027.651 ◽

2015 ◽

Vol 9 (suppl 1) ◽

pp. S346-S347

Keyword(s):

Ulcerative Colitis ◽

Drug Interaction ◽

Therapeutic Protein ◽

Protein Drug ◽

Active Ulcerative Colitis ◽

Drug Drug Interaction

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Prediction of the Impact of Cytochrome P450 2C9 Genotypes on the Drug–Drug Interaction Potential of Siponimod With Physiologically‐Based Pharmacokinetic Modeling: A Comprehensive Approach for Drug Label Recommendations

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.1547 ◽

2019 ◽

Vol 106 (5) ◽

pp. 1113-1124 ◽

Cited By ~ 4

Author(s):

Felix Huth ◽

Anne Gardin ◽

Kenichi Umehara ◽

Handan He

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Interaction Potential ◽

Comprehensive Approach ◽

Physiologically Based Pharmacokinetic Modeling ◽

Cytochrome P450 2C9 ◽

Drug Label ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

The Impact

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Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition

Food and Chemical Toxicology ◽

10.1016/j.fct.2014.03.004 ◽

2014 ◽

Vol 68 ◽

pp. 117-127 ◽

Cited By ~ 14

Author(s):

Yu Fen Zheng ◽

Soo Hyeon Bae ◽

Eu Jin Choi ◽

Jung Bae Park ◽

Sun Ok Kim ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Interaction Potential ◽

Dry Extract ◽

Udp Glucuronosyltransferase

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Investigation of the Mechanism of Therapeutic Protein-Drug Interaction Between Methotrexate and Golimumab, an Anti-TNFα Monoclonal Antibody

The AAPS Journal ◽

10.1208/s12248-018-0219-4 ◽

2018 ◽

Vol 20 (3) ◽

Cited By ~ 6

Author(s):

Weirong Wang ◽

Jocelyn Leu ◽

Rebecca Watson ◽

Zhenhua Xu ◽

Honghui Zhou

Keyword(s):

Monoclonal Antibody ◽

Drug Interaction ◽

Therapeutic Protein ◽

Protein Drug

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A Novel PBPK Modeling Approach to Assess Cytochrome P450 Mediated Drug-Drug Interaction Potential of the Cytotoxic Prodrug Evofosfamide

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12360 ◽

2018 ◽

Vol 7 (12) ◽

pp. 829-837 ◽

Cited By ~ 1

Author(s):

Christian Lüpfert ◽

Martin Dyroff ◽

Oliver von Richter ◽

Dieter Gallemann ◽

Samer El Bawab ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Interaction Potential ◽

Pbpk Modeling ◽

Modeling Approach ◽

Drug Drug Interaction

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Preclinical evaluation of drug—drug interaction potential: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 induction

Chemico-Biological Interactions ◽

10.1016/s0009-2797(97)00070-7 ◽

1997 ◽

Vol 107 (1-2) ◽

pp. 5-16 ◽

Cited By ~ 100

Author(s):

Albert P. Li ◽

Patrick Maurel ◽

Maria Jose Gomez-Lechon ◽

Larry C. Cheng ◽

Malle Jurima-Romet

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Interaction Potential ◽

Present Status ◽

Human Hepatocytes ◽

Preclinical Evaluation ◽

Primary Human Hepatocytes ◽

Cytochrome P450 Induction ◽

Drug Drug Interaction

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Pharmacokinetic Drug Interaction Potential of Risperidone With Cytochrome P450 Isozymes as Assessed by the Dextromethorphan, the Caffeine, and the Mephenytoin Test

Therapeutic Drug Monitoring ◽

10.1097/00007691-200106000-00008 ◽

2001 ◽

Vol 23 (3) ◽

pp. 228-231 ◽

Cited By ~ 21

Author(s):

Chin B. Eap ◽

Guido Bondolfi ◽

Daniele Zullino ◽

Christian Bryois ◽

Manuela Fuciec ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Interaction Potential ◽

Pharmacokinetic Drug Interaction ◽

P450 Isozymes ◽

Cytochrome P450 Isozymes ◽

Pharmacokinetic Drug

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Evaluation of Cytochrome P450 3A4-Mediated Drug–Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacokinetics ◽

10.1007/s40262-016-0412-5 ◽

2016 ◽

Vol 55 (11) ◽

pp. 1435-1445 ◽

Cited By ~ 16

Author(s):

Nageshwar R. Budha ◽

Tao Ji ◽

Luna Musib ◽

Steve Eppler ◽

Mark Dresser ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Modeling And Simulation ◽

Interaction Potential ◽

Pharmacokinetic Modeling ◽

Cytochrome P450 3A4 ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Drug Drug Interaction

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