scholarly journals Lentiviral vectors encoding short hairpin RNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in central nervous system neurones

2012 ◽  
Vol 14 (5) ◽  
pp. 299-315 ◽  
Author(s):  
Thomas H. Hutson ◽  
Edmund Foster ◽  
John M. Dawes ◽  
Robert Hindges ◽  
Rafael J. Yáñez-Muñoz ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Lentiviral Vectors ◽  
Interferon Response ◽  
Short Hairpin ◽  
Short Hairpin Rnas

scholarly journals Enhanced Central Nervous System Transduction with Lentiviral Vectors Pseudotyped with RVG/HIV-1gp41 Chimeric Envelope Glycoproteins

2013 ◽  
Vol 88 (5) ◽  
pp. 2877-2890 ◽  
Author(s):  
A. Trabalza ◽  
I. Eleftheriadou ◽  
A. Sgourou ◽  
T.-Y. Liao ◽  
P. Patsali ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Lentiviral Vectors ◽  
Envelope Glycoproteins

Type I interferon response in the central nervous system

Biochimie ◽  
2007 ◽  
Vol 89 (6-7) ◽  
pp. 770-778 ◽  
Author(s):  
Sophie Paul ◽  
Céline Ricour ◽  
Caroline Sommereyns ◽  
Frédéric Sorgeloos ◽  
Thomas Michiels
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Type I Interferon ◽  
Interferon Response ◽  
Type I ◽  
The Central Nervous System

The Astrocyte Type I Interferon Response is Essential for Protection Against Herpes Simplex Encephalitis

2021 ◽  
Author(s):  
Cooper K. Hayes ◽  
Daniel Giraldo ◽  
Douglas R. Wilcox ◽  
Richard Longnecker
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Herpes Simplex ◽  
Immune Activation ◽  
Herpes Simplex Encephalitis ◽  
Type I Interferon ◽  
Innate Immune ◽  
Interferon Response ◽  
Type I ◽  
Innate Immune Activation

Innate immune activation by central nervous system (CNS) resident cells is critical for controlling HSV-1 replication.…

scholarly journals Lentiviral vectors as tools to understand central nervous system biology in mammalian model organisms

2015 ◽  
Vol 8 ◽  
Author(s):  
Louise C. Parr-Brownlie ◽  
Clémentine Bosch-Bouju ◽  
Lucia Schoderboeck ◽  
Rachel J. Sizemore ◽  
Wickliffe C. Abraham ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
System Biology ◽  
Lentiviral Vectors ◽  
Model Organisms
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