Nitro Ketones in Organic Synthesis: A New, Short Synthesis of Racemictrans-2-methyl-1,7-dioxaspiro[5.5]undecane,trans, trans- andtrans,cis-2,8-dimethyl-1,7-dioxaspiro[5.5]undecane by Henry reaction

Due to its inherent advantages such as easy recovery and reuse of the catalysts/ reagents, and environmentally friendly nature, the heterogeneous system has gain popularity in the realm of organic synthesis. In recent years, several chemically or biologically potent molecules are achieved through heterogeneous synthesis strategies. By recalling some of the classical fundamentals of the heterogeneous system in important organic synthesis, this mini-review outlines the recent developments in the applications heterogeneous catalysts and reagents; particularly in the solid phase synthesis, esterification and transesterification reactions to produce biodiesel, and Henry reaction.

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ChemInform Abstract: α,β-Epoxy Sulfoxides as Useful Intermediates in Organic Synthesis. Part 13. The Practical Procedure for a Preparation of 1-Chloroalkyl p-Tolyl Sulfoxides (II) in High Optically Active Form: A Very Short Synthesis of Optically Active D

ChemInform ◽

10.1002/chin.198824175 ◽

1988 ◽

Vol 19 (24) ◽

Author(s):

T. SATOH ◽

T. OOHARA ◽

Y. UEDA ◽

K. YAMAKAWA

Keyword(s):

Organic Synthesis ◽

Active Form ◽

Optically Active ◽

Practical Procedure ◽

Short Synthesis

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A Short Synthesis of l-Acosamine Based on Nitroaldol Addition (Henry Reaction). Analysis of the Key Step Concerning Solvent and Temperature Effects

Synthesis ◽

10.1055/s-1999-3560 ◽

1999 ◽

Vol 1999 (09) ◽

pp. 1691-1702 ◽

Cited By ~ 12

Author(s):

Andreas Menzel

Keyword(s):

Temperature Effects ◽

Henry Reaction ◽

Short Synthesis

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DABCO as a Base and an Organocatalyst in Organic Synthesis: A Review

Current Green Chemistry ◽

10.2174/2213346107666191227101538 ◽

2020 ◽

Vol 7 (2) ◽

pp. 146-162

Author(s):

Dinesh K. Jangid

Keyword(s):

Organic Synthesis ◽

Ring Opening ◽

High Selectivity ◽

Solid Catalyst ◽

Cycloaddition Reactions ◽

Coupling Reactions ◽

Henry Reaction ◽

Environmental Friendly ◽

Ring Opening Reactions ◽

Catalytic Applications

One of the organocatalysts 1,4-diazabicyclo[2.2.2]octane (DABCO) is an excellent solid catalyst in a number of reactions. It is also a good nucleophile and a base in numerous reactions for the synthesis of heterocycles. DABCO catalyzes many reactions like cycloaddition reactions, coupling reactions, Baylis-Hillman reaction, Henry reaction, ring opening reactions, etc. One more advanced feature of these reactions is that they proceed through environmental friendly pathway. DABCO has more advantages than other organic catalysts because it is an inexpensive, non.toxic base, an ecofriendly and a highly reactive catalyst for building of organic frameworks, which produce the desired products in excellent yields with high selectivity. Many catalytic applications of DABCO have been reported for the synthesis of an organic framework which has been discussed in this review.

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Direct Synthesis of Keto Nitroaliphatics via Retro-Henry Reaction of Cyclic 2-Nitroalcohols by Anhydrous Copper Sulfate Adsorbed on Silica Gel. A Short Synthesis of (±)-Phoracantholide I

Synthesis ◽

10.1055/s-1996-4318 ◽

1996 ◽

Vol 1996 (08) ◽

pp. 981-985 ◽

Cited By ~ 18

Author(s):

Anil K. Saikia ◽

Monoj J. Hazarika ◽

Nabin C. Barua ◽

Maitreyee Sarma Bezbarua ◽

Ram P. Sharma ◽

...

Keyword(s):

Silica Gel ◽

Copper Sulfate ◽

Direct Synthesis ◽

Henry Reaction ◽

Short Synthesis

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Advances in Henry Reaction: A Versatile Method in Organic Synthesis

Mini-Reviews in Organic Chemistry ◽

10.2174/1570193x16666190214150144 ◽

2020 ◽

Vol 17 (3) ◽

pp. 297-308

Author(s):

Nidhi Singh ◽

Jaya Pandey

Keyword(s):

Green Chemistry ◽

Organic Synthesis ◽

Amino Alcohol ◽

Building Blocks ◽

Henry Reaction ◽

High Significance ◽

Modern Methods ◽

Synthetic Reactions ◽

Stereoselective Reactions ◽

Synthetic Routes

: Henry reaction is an important reaction employing carbonyls which furnishes β-nitro alcohol, nitroalkene, α-nitro ketones, β-amino alcohol as products and byproducts that may be transfigured as building blocks for other synthetic reactions. This paper focuses on various synthetic routes for Henry reaction, a versatile reaction of high significance in organic synthesis. The paper discusses the chemistry and plausible products of the reaction, along with the various available synthetic routes for the same, ranging from classical conventional methods to modern methods of green chemistry trends. Use of various catalysts as rate enhancer as well as use of various catalysts as enantioselective frontman for stereoselective reactions, have been described in this work.

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