Investigations of Dianhydro‐D ‐glucitol adsorbed on AuNPs surface: In silico and in vitro approach based on anticancer activity studies against A549 lung cancer cell lines

Author(s):  
Shyni V. ◽  
Leenaraj D. R. ◽  
Lynnette Joseph ◽  
D. Sajan
2018 ◽  
Vol Volume 12 ◽  
pp. 1881-1904 ◽  
Author(s):  
Marcel Nel ◽  
Annie Joubert ◽  
Wolfgang Dohle ◽  
Barry Potter ◽  
Anne Theron

2013 ◽  
Vol 8 (12) ◽  
pp. 1934578X1300801 ◽  
Author(s):  
Sumit S Chourasiya ◽  
Eppakayala Sreedhar ◽  
K. Suresh Babu ◽  
Nagula Shankaraiah ◽  
V. Lakshma Nayak ◽  
...  

Bioactivity guided investigation of the DCM: MeOH (1:1) extract from the rhizomes of Alpinia galanga led to the isolation of phenylpropanoids (1–9) and their structures were established by 1H NMR, 13C NMR, IR and LC-MS/MS. These compounds have been evaluated for their in vitro anticancer activity against the human cancer cell lines A549 (lung cancer), Colo-205 (colon cancer), A431 (skin cancer), NCI H460 (lung cancer), PC-3 (prostate cancer), and HT-29 (colon cancer). Compounds 4 and 9 showed potent anticancer activity (ranging from 1.3–19.7 μg/mL) against all the tested cancer cell lines. In addition, an asymmetric synthesis of acetoxychavicol acetate (1) and trans-p-coumaryl alcohol (4) has been accomplished in six steps starting from readily available p-hydroxybenzaldehyde for the first time. Grignard reaction and Sharpless kinetic resolution reactions were utilized as the key steps to install the basic core.


PLoS ONE ◽  
2020 ◽  
Vol 15 (5) ◽  
pp. e0231437
Author(s):  
Qing-lin Niu ◽  
Hui Sun ◽  
Chao Liu ◽  
Juan Li ◽  
Chang-xu Liang ◽  
...  

2010 ◽  
Vol 28 (15_suppl) ◽  
pp. e21016-e21016 ◽  
Author(s):  
P. M. Marconi ◽  
K. Patel ◽  
L. Thimothy ◽  
S. Buchanan ◽  
M. J. Liptay ◽  
...  

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