Contiguous-slice zonally oblique multislice (CO-ZOOM) diffusion tensor imaging: Examples of in vivo spinal cord and optic nerve applications

2009 ◽  
Vol 29 (2) ◽  
pp. 454-460 ◽  
Author(s):  
Nicholas G. Dowell ◽  
Thomas M. Jenkins ◽  
Olga Ciccarelli ◽  
David H. Miller ◽  
Claudia A.M. Wheeler-Kingshott
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Optic Nerve ◽  
Diffusion Tensor ◽  
Contiguous Slice

In vivo diffusion tensor imaging of rat spinal cord at 7 T

2002 ◽  
Vol 20 (3) ◽  
pp. 243-247 ◽  
Author(s):  
Ibrahim Elshafiey ◽  
Mehmet Bilgen ◽  
Renjie He ◽  
Ponnada A. Narayana
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Rat Spinal Cord

In vivo diffusion tensor imaging of the human optic nerve: Pilot study in normal controls

2006 ◽  
Vol 56 (2) ◽  
pp. 446-451 ◽  
Author(s):  
C.A.M. Wheeler-Kingshott ◽  
S.A. Trip ◽  
M.R. Symms ◽  
G.J.M. Parker ◽  
G.J. Barker ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Pilot Study ◽  
Optic Nerve ◽  
Diffusion Tensor ◽  
Human Optic Nerve ◽  
Normal Controls

scholarly journals Improved in vivo diffusion tensor imaging of human cervical spinal cord

NeuroImage ◽  
2013 ◽  
Vol 67 ◽  
pp. 64-76 ◽  
Author(s):  
Junqian Xu ◽  
Joshua S. Shimony ◽  
Eric C. Klawiter ◽  
Abraham Z. Snyder ◽  
Kathryn Trinkaus ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Cervical Spinal Cord

In Vivo Characterization of Transport Anisotropy in Rat Spinal Cord Using Diffusion Tensor Imaging

2008 ◽  
Author(s):  
Xiaoming Chen ◽  
Garrett W. Astary ◽  
Thomas H. Mareci ◽  
Malisa Sarntinoranont
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Drug Transport ◽  
Diffusion Tensor ◽  
Local Drug Delivery ◽  
Imaging Method ◽  
Rat Spinal Cord ◽  
In Vivo Characterization

Biotransport in nervous tissues is complicated by the existence of neural fibers. These axonal fibers result in inhomogeneous and anisotropic extracellular transport, which complicates the prediction of local drug delivery such as convection-enhanced delivery [1]. Previous studies by our group [4] have shown that by using diffusion tensor imaging (DTI) [2, 3], anisotropic transport in rat spinal cord can be modeled using computational models, and consequently extracellular flows which influence drug transport can be well predicted. In previous studies, DTI-based models used data from an excised and fixed rat spinal cord. In the current study, we extend our DTI study to in vivo measures, and report the in vivo characterization of transport anisotropy in rat spinal cord. The MR imaging method is presented and the DTI data is discussed.

In vivo diffusion tensor imaging of chronic spinal cord compression: a rat model with special attention to the conus medullaris

2016 ◽  
Vol 57 (12) ◽  
pp. 1531-1539 ◽  
Author(s):  
Peng Zhao ◽  
Chao Kong ◽  
Xueming Chen ◽  
Hua Guan ◽  
Zhenshan Yu ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Spinal Cord Compression ◽  
Rat Model ◽  
Diffusion Tensor ◽  
Cord Compression ◽  
Conus Medullaris

scholarly journals Serial Diffusion Tensor Imaging In Vivo Predicts Long-Term Functional Recovery and Histopathology in Rats following Different Severities of Spinal Cord Injury

2016 ◽  
Vol 33 (10) ◽  
pp. 917-928 ◽  
Author(s):  
Samir P. Patel ◽  
Taylor D. Smith ◽  
Jenna L. VanRooyen ◽  
David Powell ◽  
David H. Cox ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Diffusion Tensor Imaging ◽  
Functional Recovery ◽  
Diffusion Tensor ◽  
Cord Injury

In vivo serial diffusion tensor imaging of experimental spinal cord injury

2006 ◽  
Vol 83 (5) ◽  
pp. 801-810 ◽  
Author(s):  
Aparna A. Deo ◽  
Raymond J. Grill ◽  
Khader M. Hasan ◽  
Ponnada A. Narayana
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Experimental Spinal Cord Injury ◽  
Cord Injury

scholarly journals Spontaneous acute and chronic spinal cord injuries in paraplegic dogs: a comparative study of in vivo diffusion tensor imaging

Spinal Cord ◽  
2017 ◽  
Vol 55 (12) ◽  
pp. 1108-1116 ◽  
Author(s):  
A Wang-Leandro ◽  
M K Hobert ◽  
N Alisauskaite ◽  
P Dziallas ◽  
K Rohn ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Comparative Study ◽  
Spinal Cord Injuries ◽  
Diffusion Tensor

scholarly journals The value of quantitative diffusion tensor imaging indices of spinal cord disorders

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Mohammad Koriem Mahmoud Omar ◽  
Abd El-Karem Hasan Abd Allah ◽  
Mona Gouda Maghrabi ◽  
Mohamed Zidan Mohamed
Keyword(s):  
Spinal Cord ◽  
Diffusion Tensor Imaging ◽  
Fractional Anisotropy ◽  
Diffusion Tensor ◽  
Tissue Injury ◽  
Volume Ratio ◽  
Roc Curve Analysis ◽  
Significant Difference ◽  
Spinal Cord Disorders

Abstract Background Different lesions affecting the spinal cord can lead to myelopathy. Diffusion tensor imaging (DTI) is widely used to predict the degree of spinal cord microstructure affection and to assess axonal integrity and diffusion directionality. We hypothesized that not all DTI parameters have the same affection with different spinal cord pathologies. The purpose of this study is to assess the value of the quantitative diffusion tensor imaging indices in different spinal cord lesions. Results There is highly statistically significant difference of the fractional anisotropy (FA), relative anisotropy (RA), volume ratio (VR) and secondary eigenvector values (E2 and E3) between various studied cord lesions and control levels. There is no statistically significant difference of the apparent diffusion coefficient (ADC) and the primary eigenvector value (E1) (ANOVA test). The ROC curve analysis showed the higher sensitivity and accuracy were ‘88% and 62.5%, respectively,’ with FA cutoff value about 0.380. Conclusion The resulted quantitative DTI indices ‘fractional anisotropy, relative anisotropy, volume ratio and secondary eigenvalues’ work as a numerical in vivo marker of overall tissue injury in different pathologies affecting the spinal cord.

Sign in / Sign up

Export Citation Format

Share Document