Long-term fate of human telencephalic progenitor cells grafted into the adult mouse brain: Effects of previous amplification in vitro

2002 ◽  
Vol 68 (3) ◽  
pp. 276-283 ◽  
Author(s):  
Delphine Buchet ◽  
Marie-Hélène Buc-Caron ◽  
Olivier Sabaté ◽  
François Lachapelle ◽  
Jacques Mallet
Stem Cells ◽  
2008 ◽  
Vol 26 (4) ◽  
pp. 979-987 ◽  
Author(s):  
Mohammad G. Golmohammadi ◽  
Daniel G. Blackmore ◽  
Beatrice Large ◽  
Hassan Azari ◽  
Ebrahim Esfandiary ◽  
...  

2006 ◽  
Vol 27 (4) ◽  
pp. 606-613 ◽  
Author(s):  
M. Calafiore ◽  
G. Battaglia ◽  
A. Zappalà ◽  
E. Trovato-Salinaro ◽  
F. Caraci ◽  
...  

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Yoshihiko Yamazaki ◽  
Yoshifumi Abe ◽  
Satoshi Fujii ◽  
Kenji F. Tanaka

AbstractThe juvenile brain presents plasticity. Oligodendrocytes are the myelinating cells of the central nervous system and myelination can be adaptive. Plasticity decreases from juvenile to adulthood. The mechanisms involving oligodendrocytes underlying plasticity are unclear. Here, we show Na+-K+-Cl– co-transporter 1 (NKCC1), highly expressed in the juvenile mouse brain, regulates the oligodendrocyte activity from juvenile to adulthood in mice, as shown by optogenetic manipulation of oligodendrocytes. The reduced neuronal activity in adults was restored by Nkcc1 overexpression in oligodendrocytes. Moreover, in adult mice overexpressing Nkcc1, long-term potentiation and learning were facilitated compared to age-matched controls. These findings demonstrate that NKCC1 plays a regulatory role in the age-dependent activity of oligodendrocytes, furthermore inducing activation of NKCC1 in oligodendrocytes can restore neuronal plasticity in the adult mouse brain.


1991 ◽  
Vol 88 (16) ◽  
pp. 7016-7020 ◽  
Author(s):  
V. W. Yong ◽  
R. Moumdjian ◽  
F. P. Yong ◽  
T. C. Ruijs ◽  
M. S. Freedman ◽  
...  

PLoS ONE ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. e31401 ◽  
Author(s):  
Stefano Falone ◽  
Antonella D'Alessandro ◽  
Alessandro Mirabilio ◽  
Giacomo Petruccelli ◽  
Marisa Cacchio ◽  
...  

2016 ◽  
Vol 75 (9) ◽  
pp. 843-854 ◽  
Author(s):  
Idris A. Azeez ◽  
Funmilayo Olopade ◽  
Claudia Laperchia ◽  
Anna Andrioli ◽  
Ilaria Scambi ◽  
...  

2011 ◽  
Vol 117 (3) ◽  
pp. 208-212 ◽  
Author(s):  
Koichi Kawada ◽  
Masayuki Kaneko ◽  
Yasuyuki Nomura ◽  
Seisuke Mimori ◽  
Hiroshi Hamana ◽  
...  

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