The beneficial role of the synthetic microneurotrophin BNN20 in a focal demyelination model

2021 ◽  
Vol 99 (5) ◽  
pp. 1474-1495
Author(s):  
Ilias Kalafatakis ◽  
Alexandros Patellis ◽  
Ioannis Charalampopoulos ◽  
Achille Gravanis ◽  
Domna Karagogeos
Keyword(s):  
Beneficial Role ◽  
Focal Demyelination

The role of vitamin D in metabolic and reproductive disturbances of polycystic ovary syndrome: A narrative mini-review

2020 ◽  
pp. 1-8
Author(s):  
Daniela Menichini ◽  
Gianpiero Forte ◽  
Beatrice Orrù ◽  
Giuseppe Gullo ◽  
Vittorio Unfer ◽  
...  
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Embryo Quality ◽  
Polycystic Ovary ◽  
Vitamin D Supplementation ◽  
Endometrial Receptivity ◽  
Metabolic Disturbances ◽  
Ovary Syndrome ◽  
Beneficial Role

Abstract. Vitamin D is a secosteroid hormone that plays a pivotal role in several metabolic and reproductive pathways in humans. Increasing evidence supports the role of vitamin D deficiency in metabolic disturbances and infertility in women with polycystic ovary syndrome (PCOS). Indeed, supplementation with vitamin D seems to have a beneficial role on insulin resistance and endometrial receptivity. On the other hand, exceedingly high levels of vitamin D appear to play a detrimental role on oocytes development and embryo quality. In the current review, we summarize the available evidence about the topic, aiming to suggest the best supplementation strategy in women with PCOS or, more generally, in those with metabolic disturbances and infertility. Based on the retrieved data, vitamin D seems to have a beneficial role on IR, insulin sensitivity and endometrial receptivity, but high levels and incorrect timing of administration seem to have a detrimental role on oocytes development and embryo quality. Therefore, we encourage a low dose supplementation (400–800 IU/day) particularly in vitamin D deficient women that present metabolic disturbances like PCOS. As far as the reproductive health, we advise vitamin D supplementation in selected populations, only during specific moments of the ovarian cycle, to support the luteal phase. However, ambiguities about dosage and timing of the supplementation still emerge from the clinical studies published to date and further studies are required.

scholarly journals I Like the Way You Eat It: Lemur (Indri indri) Gut Mycobiome and Geophagy

2021 ◽  
Author(s):  
Luigimaria Borruso ◽  
Alice Checcucci ◽  
Valeria Torti ◽  
Federico Correa ◽  
Camillo Sandri ◽  
...  
Keyword(s):  
Plant Material ◽  
Soil Characteristics ◽  
Nutrient Supply ◽  
Fungal Species ◽  
High Concentration ◽  
Beneficial Role ◽  
Intimate Connection ◽  
Indri Indri ◽  
Lemur Species

AbstractHere, we investigated the possible linkages among geophagy, soil characteristics, and gut mycobiome of indri (Indri indri), an endangered lemur species able to survive only in wild conditions. The soil eaten by indri resulted in enriched secondary oxide-hydroxides and clays, together with a high concentration of specific essential micronutrients. This could partially explain the role of the soil in detoxification and as a nutrient supply. Besides, we found that soil subject to geophagy and indris’ faeces shared about 8.9% of the fungal OTUs. Also, several genera (e.g. Fusarium, Aspergillus and Penicillium) commonly associated with soil and plant material were found in both geophagic soil and indri samples. On the contrary, some taxa with pathogenic potentials, such as Cryptococcus, were only found in indri samples. Further, many saprotrophs and plant-associated fungal taxa were detected in the indri faeces. These fungal species may be involved in the digestion processes of leaves and could have a beneficial role in their health. In conclusion, we found an intimate connection between gut mycobiome and soil, highlighting, once again, the potential consequent impacts on the wider habitat.

Tannic Acid as a Natural Ferroptosis Inhibitor: Mechanisms and Beneficial Role of 3’‐ O ‐Galloylation

2021 ◽  
Vol 6 (7) ◽  
pp. 1562-1569
Author(s):  
Yangping Liu ◽  
Xican Li ◽  
Yujie Hua ◽  
Wenhui Zhang ◽  
Xianxi Zhou ◽  
...  
Keyword(s):  
Tannic Acid ◽  
Beneficial Role

Beneficial role of SiO2 plugging in AlCl3 heterogenized plugged hexagonal templated silica (PHTS) for the isopropylation of m-cresol

2007 ◽  
Vol 8 (7) ◽  
pp. 1080-1087 ◽  
Author(s):  
S. Sreevardhan Reddy ◽  
V. Siva Kumar ◽  
A.H. Padmasri ◽  
C.V.V. Satyanarayana ◽  
B. David Raju ◽  
...  
Keyword(s):  
Beneficial Role

The beneficial role of Y-implantation on the aqueous corrosion of stainless steel

2011 ◽  
Vol 205 (11) ◽  
pp. 3506-3511 ◽  
Author(s):  
F. Noli ◽  
P. Misaelides ◽  
E. Pavlidou
Keyword(s):  
Stainless Steel ◽  
Aqueous Corrosion ◽  
Beneficial Role

Beneficial role of vitamin D3in the prevention of certain respiratory diseases

2013 ◽  
Vol 7 (6) ◽  
pp. 327-350 ◽  
Author(s):  
Khanh vinh quốc Lương ◽  
Lan Thi Hoàng Nguyễn
Keyword(s):  
Respiratory Diseases ◽  
Beneficial Role

scholarly journals Beneficial role of overexpression of TFPI-2 on tumour progression in human small cell lung cancer

FEBS Open Bio ◽  
2013 ◽  
Vol 3 (1) ◽  
pp. 291-301 ◽  
Author(s):  
Marion Lavergne ◽  
Marie-Lise Jourdan ◽  
Claire Blechet ◽  
Serge Guyetant ◽  
Alain Le Pape ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Tumour Progression ◽  
Small Cell ◽  
Small Cell Lung ◽  
Beneficial Role

Riceberry rice beverage decreases postprandial glycemic response, inflammatory markers and antioxidant status induced by a high carbohydrate and moderate fat meal in overweight and obese men

2022 ◽  
Author(s):  
Tanisa anuyahong ◽  
Charoonsri Chusak ◽  
Sirichai Adisakwattana
Keyword(s):  
Clinical Studies ◽  
Inflammatory Markers ◽  
Healthy Subjects ◽  
Antioxidant Status ◽  
Current Work ◽  
Glycemic Response ◽  
High Carbohydrate ◽  
Beneficial Role ◽  
Fat Meal

Recent clinical studies support the beneficial role of riceberry rice and its food products on controlling glycemic response in healthy subjects. The aim of the current work was to determine...

scholarly journals Things go better with coke: the beneficial role of carbonaceous deposits in heterogeneous catalysis

2016 ◽  
Vol 6 (2) ◽  
pp. 363-378 ◽  
Author(s):  
C. H. Collett ◽  
J. McGregor
Keyword(s):  
Heterogeneous Catalysis ◽  
Heterogeneous Catalysts ◽  
Catalyst Deactivation ◽  
Catalytic Performance ◽  
Fischer Tropsch ◽  
Carbonaceous Deposits ◽  
Beneficial Role ◽  
Catalytic Processes

Carbonaceous deposits on heterogeneous catalysts are traditionally associated with catalyst deactivation. However, they can play a beneficial role in many catalytic processes, e.g. dehydrogenation, hydrogenation, alkylation, isomerisation, Fischer–Tropsch, MTO etc. This review highlights the role and mechanism by which coke deposits can enhance catalytic performance.

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