Nerve growth factor (NGF) receptors in a central nervous system glial cell line: Upregulation by NGF and brain-derived neurotrophic factor

1992 ◽  
Vol 33 (1) ◽  
pp. 82-90 ◽  
Author(s):  
P. E. Spoerri ◽  
S. Romanello ◽  
L. Petrelli ◽  
A. Negro ◽  
R. Dal Toso ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Cell Line ◽  
Glial Cell ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Nerve Growth

scholarly journals The roles of glial cell line-derived neurotrophic factor, brain-derived neurotrophic factor and nerve growth factor during the final stage of folliculogenesis: a focus on oocyte maturation

Reproduction ◽  
2013 ◽  
Vol 145 (2) ◽  
pp. R43-R54 ◽  
Author(s):  
Katja Linher-Melville ◽  
Julang Li
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Cell Line ◽  
Glial Cell ◽  
Oocyte Maturation ◽  
Neurotrophic Factor ◽  
Final Stage ◽  
Brain Derived Neurotrophic Factor ◽  
Peripheral Tissues ◽  
Nerve Growth

Neurotrophic factors were first identified to promote the growth, survival or differentiation of neurons and have also been associated with the early stages of ovarian folliculogenesis. More recently, their effects on the final stage of follicular development, including oocyte maturation and early embryonic development, have been reported. Glial cell line-derived neurotrophic factor (GDNF), brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), which are expressed in numerous peripheral tissues outside of the CNS, most notably the ovary, are now known to stimulate oocyte maturation in various species, also enhancing developmental competence. The mechanisms that underlie their actions in antral follicles, as well as the targets ultimately controlled by these factors, are beginning to emerge. GDNF, BDNF and NGF, alone or in combination, could be added to the media currently utilized forin vitrooocyte maturation, thereby potentially increasing the production and/or quality of early embryos.

Nerve Growth Factor Regulates the Expression of Brain-Derived Neurotrophic Factor mRNA in the Peripheral Nervous System

1996 ◽  
Vol 7 (2) ◽  
pp. 134-142 ◽  
Author(s):  
Stuart C. Apfel ◽  
Douglas E. Wright ◽  
Andrea M. Wiideman ◽  
Christine Dormia ◽  
William D. Snider ◽  
...  
Keyword(s):  
Nervous System ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Peripheral Nervous System ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Nerve Growth
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