Nanostructured gold surfaces as reproducible substrates for surface-enhanced Raman spectroscopy

2007 ◽  
Vol 38 (3) ◽  
pp. 277-282 ◽  
Author(s):  
M. Sackmann ◽  
S. Bom ◽  
T. Balster ◽  
A. Materny
2018 ◽  
Vol 49 (7) ◽  
pp. 1184-1189 ◽  
Author(s):  
A. Merlen ◽  
C. Pardanaud ◽  
S. Coussan ◽  
C. Panagiotopoulos ◽  
O. Grauby ◽  
...  

2005 ◽  
Vol 77 (13) ◽  
pp. 4013-4019 ◽  
Author(s):  
Douglas A. Stuart ◽  
Chanda Ranjit Yonzon ◽  
Xiaoyu Zhang ◽  
Olga Lyandres ◽  
Nilam C. Shah ◽  
...  

Gold Bulletin ◽  
2013 ◽  
Vol 46 (4) ◽  
pp. 283-290 ◽  
Author(s):  
A. Bouvrée ◽  
A. D’Orlando ◽  
T. Makiabadi ◽  
S. Martin ◽  
G. Louarn ◽  
...  

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.


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