Use of Raman and Raman optical activity for the structural characterization of a therapeutic monoclonal antibody formulation subjected to heat stress

2015 ◽  
Vol 46 (6) ◽  
pp. 531-536 ◽  
Author(s):  
Geetha Thiagarajan ◽  
Effendi Widjaja ◽  
Jun Hyuk Heo ◽  
Jason K. Cheung ◽  
Busolo Wabuyele ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Heat Stress ◽  
Optical Activity ◽  
Structural Characterization ◽  
Therapeutic Monoclonal Antibody ◽  
Raman Optical Activity

Structural characterization of proteins and viruses using Raman optical activity

2004 ◽  
Vol 35 (1-2) ◽  
pp. 87-92 ◽  
Author(s):  
Ewan W Blanch ◽  
Iain H McColl ◽  
Lutz Hecht ◽  
Kurt Nielsen ◽  
Laurence D Barron
Keyword(s):  
Optical Activity ◽  
Structural Characterization ◽  
Raman Optical Activity

Raman optical activity characterization of native and molten globule states of equine lysozyme: Comparison with hen lysozyme and bovine α-lactalbumin

Biopolymers ◽  
2000 ◽  
Vol 57 (4) ◽  
pp. 235-248 ◽  
Author(s):  
Ewan W. Blanch ◽  
Ludmilla A. Morozova-Roche ◽  
Lutz Hecht ◽  
Wim Noppe ◽  
Laurence D. Barron
Keyword(s):  
Optical Activity ◽  
Molten Globule ◽  
Raman Optical Activity

Structural characterization of N-linked oligosaccharides on monoclonal antibody Nimotuzumab through process development

Biologicals ◽  
2012 ◽  
Vol 40 (4) ◽  
pp. 288-298 ◽  
Author(s):  
Raquel Montesino ◽  
Loany Calvo ◽  
Antonio Vallin ◽  
Pauline M. Rudd ◽  
David J. Harvey ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Structural Characterization ◽  
Process Development

Structural Characterization of a Monoclonal Antibody–Maytansinoid Immunoconjugate

2015 ◽  
Vol 88 (1) ◽  
pp. 695-702 ◽  
Author(s):  
Quanzhou Luo ◽  
Hyo Helen Chung ◽  
Christopher Borths ◽  
Matthew Janson ◽  
Jie Wen ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Structural Characterization

Vibrational Raman Optical Activity Characterization of Poly(l-proline) II Helix in Alanine Oligopeptides

2004 ◽  
Vol 126 (16) ◽  
pp. 5076-5077 ◽  
Author(s):  
Iain H. McColl ◽  
Ewan W. Blanch ◽  
Lutz Hecht ◽  
Neville R. Kallenbach ◽  
Laurence D. Barron
Keyword(s):  
Optical Activity ◽  
Raman Optical Activity

Vibrational optical activity for structural characterization of natural products

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Vol 37 (12) ◽  
pp. 1661-1699 ◽  
Author(s):  
Prasad L. Polavarapu ◽  
Ernesto Santoro
Keyword(s):  
Natural Products ◽  
Optical Activity ◽  
Structural Characterization ◽  
Recent Progress

This review presents the recent progress towards elucidating the structures of chiral natural products and applications using vibrational optical activity (VOA) spectroscopy.

Structural characterization of the ‘melanoma-specific’ antigen detected by monoclonal antibody 691I5Nu-4-B

1981 ◽  
Vol 18 (3) ◽  
pp. 207-218 ◽  
Author(s):  
K.F. Mitchell ◽  
J.P. Fuhrer ◽  
Z. Steplewski ◽  
H. Koprowski
Keyword(s):  
Monoclonal Antibody ◽  
Structural Characterization ◽  
Specific Antigen

Structural Characterization of a Recombinant Monoclonal Antibody by Electrospray Time-of-Flight Mass Spectrometry

2005 ◽  
Vol 22 (8) ◽  
pp. 1338-1349 ◽  
Author(s):  
Lintao Wang ◽  
Godfrey Amphlett ◽  
John M. Lambert ◽  
Walter Blättler ◽  
Wei Zhang
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibody ◽  
Structural Characterization ◽  
Time Of Flight ◽  
Recombinant Monoclonal Antibody ◽  
Flight Mass Spectrometry
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