Optimization of ultrasound-assisted extraction of phenolic compounds from grapefruit (Citrus paradisiMacf.) leaves via D-optimal design and artificial neural network design with categorical and quantitative variables

2018 ◽  
Vol 98 (12) ◽  
pp. 4584-4596 ◽  
Author(s):  
Zeynep Ciğeroğlu ◽  
Ömür Aras ◽  
Carlos A Pinto ◽  
Mahmut Bayramoglu ◽  
Ş İsmail Kırbaşlar ◽  
...  
Keyword(s):  
Neural Network ◽  
Artificial Neural Network ◽  
Phenolic Compounds ◽  
Optimal Design ◽  
Network Design ◽  
Ultrasound Assisted Extraction ◽  
Assisted Extraction ◽  
Ultrasound Assisted ◽  
Artificial Neural

Artificial Neural Network Modeling of Ultrasound-Assisted Polysaccharides Extraction from Potentilla anserina and Anti-Platelet Aggregation Activity

2014 ◽  
Vol 618 ◽  
pp. 367-375 ◽  
Author(s):  
Tao Guo ◽  
Jun Qing Wei ◽  
Ya Wang ◽  
Dan Su ◽  
Zhen Zhang ◽  
...  
Keyword(s):  
Neural Network ◽  
Artificial Neural Network ◽  
Platelet Aggregation ◽  
Neural Network Modeling ◽  
Process Conditions ◽  
Ultrasound Assisted Extraction ◽  
Assisted Extraction ◽  
Potentilla Anserina ◽  
Ultrasound Assisted ◽  
Artificial Neural

In this study, Ultrasound-assisted extraction (UAE) was used for polysaccharides extraction from Potentilla anserina. A computer-stimulated artificial neural network (ANN) was developed to get a correlation between the input variables and the output parameter. Finally, the optimal process conditions were obtained as follows: extraction temperature 55 °C, extraction time 55 min, ratio of liquid to solid 20:1, power 175 W. Under optimized conditions, ultrasound-assisted extraction had obviously higher yield of polysaccharides than the traditional heat reflux method. The optimization procedure showed a close interaction between the experimental and simulated values for polysaccharides extraction. The R2 (0.99271) and MSE (0.0425) values of model suggested good fitness and generalization of the ANN. Moreover, the results also indicated that polysaccharides have inhibitory effect on ADP-induced platelet aggregation.

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