New insights into docosahexaenoic acid homeostasis during age-;related cognitive decline

2014 ◽  
Vol 26 (4) ◽  
pp. 79-81
Author(s):  
Marie Hennebelle ◽  
Christian-Alexandre Castellano ◽  
Mélanie Plourde
Keyword(s):  
Docosahexaenoic Acid ◽  
Cognitive Decline ◽  
Age Related ◽  
Age Related Cognitive Decline

scholarly journals The Interest of Adding Micronutrients to Docosahexaenoic Acid Supplementation to Prevent Age-Related Cognitive Decline

2018 ◽  
Vol 08 (03) ◽  
Author(s):  
Mathilde Chataigner ◽  
Anne-Laure Dinel ◽  
Veronique Pallet ◽  
Sophie Laye ◽  
Corinne Joffre
Keyword(s):  
Docosahexaenoic Acid ◽  
Cognitive Decline ◽  
Acid Supplementation ◽  
Age Related ◽  
Age Related Cognitive Decline

O1-04-01: Results of the MIDAS trial: Effects of docosahexaenoic acid on physiological and safety parameters in age-related cognitive decline

2009 ◽  
Vol 5 (4S_Part_3) ◽  
pp. P84-P84 ◽  
Author(s):  
Karin Yurko-Mauro ◽  
Deanna McCarthy ◽  
Eileen Bailey-Hall ◽  
Edward B. Nelson ◽  
Andrew Blackwell ◽  
...  
Keyword(s):  
Docosahexaenoic Acid ◽  
Cognitive Decline ◽  
Age Related ◽  
Safety Parameters ◽  
Age Related Cognitive Decline

Beneficial effects of docosahexaenoic acid on cognition in age-related cognitive decline

2010 ◽  
Vol 6 (6) ◽  
pp. 456-464 ◽  
Author(s):  
Karin Yurko-Mauro ◽  
Deanna McCarthy ◽  
Dror Rom ◽  
Edward B. Nelson ◽  
Alan S. Ryan ◽  
...  
Keyword(s):  
Docosahexaenoic Acid ◽  
Cognitive Decline ◽  
Beneficial Effects ◽  
Age Related ◽  
Age Related Cognitive Decline

Activity Engagement in Cognitive Aging: A Review of the Evidence

2013 ◽  
Vol 23 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Yvonne Rogalski ◽  
Muriel Quintana
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Cognitive Aging ◽  
Social Activity ◽  
Current Evidence ◽  
Omega 3 ◽  
Neuroprotective Effects ◽  
Activity Engagement ◽  
Age Related ◽  
Age Related Cognitive Decline

The population of older adults is rapidly increasing, as is the number and type of products and interventions proposed to prevent or reduce the risk of age-related cognitive decline. Advocacy and prevention are part of the American Speech-Language-Hearing Association’s (ASHA’s) scope of practice documents, and speech-language pathologists must have basic awareness of the evidence contributing to healthy cognitive aging. In this article, we provide a brief overview outlining the evidence on activity engagement and its effects on cognition in older adults. We explore the current evidence around the activities of eating and drinking with a discussion on the potential benefits of omega-3 fatty acids, polyphenols, alcohol, and coffee. We investigate the evidence on the hypothesized neuroprotective effects of social activity, the evidence on computerized cognitive training, and the emerging behavioral and neuroimaging evidence on physical activity. We conclude that actively aging using a combination of several strategies may be our best line of defense against cognitive decline.

Occupational differences in age-related cognitive decline

2008 ◽  
Author(s):  
J. Grosch ◽  
T. Alterman ◽  
J. Li ◽  
G. Fisher
Keyword(s):  
Cognitive Decline ◽  
Occupational Differences ◽  
Age Related ◽  
Age Related Cognitive Decline

scholarly journals Targeting impaired nutrient sensing with repurposed therapeutics to prevent or treat age-related cognitive decline and dementia: A systematic review

2021 ◽  
Vol 67 ◽  
pp. 101302
Author(s):  
Benjamin Kioussis ◽  
Camilla S.L. Tuttle ◽  
Daniel S. Heard ◽  
Brian K. Kennedy ◽  
Nicola T. Lautenschlager ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Decline ◽  
Nutrient Sensing ◽  
Age Related ◽  
Age Related Cognitive Decline

scholarly journals Gene Expression Profile in Different Age Groups and Its Association with Cognitive Function in Healthy Malay Adults in Malaysia

Cells ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1611
Author(s):  
Nur Fathiah Abdul Abdul Sani ◽  
Ahmad Imran Zaydi Amir Amir Hamzah ◽  
Zulzikry Hafiz Abu Abu Bakar ◽  
Yasmin Anum Mohd Mohd Yusof ◽  
Suzana Makpol ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cognitive Decline ◽  
Cognitive Aging ◽  
Successful Aging ◽  
Expression Patterns ◽  
Age Groups ◽  
Genetic Network ◽  
Cross Sectional ◽  
Age Related ◽  
Age Related Cognitive Decline

The mechanism of cognitive aging at the molecular level is complex and not well understood. Growing evidence suggests that cognitive differences might also be caused by ethnicity. Thus, this study aims to determine the gene expression changes associated with age-related cognitive decline among Malay adults in Malaysia. A cross-sectional study was conducted on 160 healthy Malay subjects, aged between 28 and 79, and recruited around Selangor and Klang Valley, Malaysia. Gene expression analysis was performed using a HumanHT-12v4.0 Expression BeadChip microarray kit. The top 20 differentially expressed genes at p < 0.05 and fold change (FC) = 1.2 showed that PAFAH1B3, HIST1H1E, KCNA3, TM7SF2, RGS1, and TGFBRAP1 were regulated with increased age. The gene set analysis suggests that the Malay adult’s susceptibility to developing age-related cognitive decline might be due to the changes in gene expression patterns associated with inflammation, signal transduction, and metabolic pathway in the genetic network. It may, perhaps, have important implications for finding a biomarker for cognitive decline and offer molecular targets to achieve successful aging, mainly in the Malay population in Malaysia.

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