scholarly journals Systematic analysis of the kalimantacin assembly line NRPS module using an adapted targeted mutagenesis approach

2015 ◽  
Vol 5 (2) ◽  
pp. 279-286 ◽  
Author(s):  
Birgit Uytterhoeven ◽  
Kenny Appermans ◽  
Lijiang Song ◽  
Joleen Masschelein ◽  
Thomas Lathouwers ◽  
...  
Author(s):  
Richard Carr ◽  
Frederick C. Ashford ◽  
Ronald S. Easterby

The need to export, and the high-quantity production capabilities of a new precision assembly line, stimulated the development of a new line of center lathes for world markets. A survey of international requirements established basic performance capabilities and features. The industrial designer, in conjunction with the manufacturer's engineering organization, developed an appearance design concept that was adaptable to machines of varying sizes and proportions, that was compatible with the unique manufacturing facilities, and that conveyed a strong, recognizable company style. The human factors specialist collaborated with the industrial designer in the design of the operator's workplace, controls and displays, and through a systematic analysis of operator tasks, devised a new, more effective display for translating maching instructions specified on an engineering drawing into control settings on the lathe. Results of the industrial design and ergonomic analyses are illustrated and discussed.


Author(s):  
F.J. Sjostrand

In the 1940's and 1950's electron microscopy conferences were attended with everybody interested in learning about the latest technical developments for one very obvious reason. There was the electron microscope with its outstanding performance but nobody could make very much use of it because we were lacking proper techniques to prepare biological specimens. The development of the thin sectioning technique with its perfectioning in 1952 changed the situation and systematic analysis of the structure of cells could now be pursued. Since then electron microscopists have in general become satisfied with the level of resolution at which cellular structures can be analyzed when applying this technique. There has been little interest in trying to push the limit of resolution closer to that determined by the resolving power of the electron microscope.


2019 ◽  
Vol 19 (4) ◽  
pp. 78-90
Author(s):  
Theresa McCulla

In 1965, Frederick (Fritz) Maytag III began a decades-long revitalization of Anchor Brewing Company in San Francisco, California. This was an unexpected venture from an unlikely brewer; for generations, Maytag's family had run the Maytag Washing Machine Company in Iowa and he had no training in brewing. Yet Maytag's career at Anchor initiated a phenomenal wave of growth in the American brewing industry that came to be known as the microbrewing—now “craft beer”—revolution. To understand Maytag's path, this article draws on original oral histories and artifacts that Maytag donated to the Smithsonian Institution's National Museum of American History via the American Brewing History Initiative, a project to document the history of brewing in the United States. The objects and reflections that Maytag shared with the museum revealed a surprising link between the birth of microbrewing and the strategies and culture of mass manufacturing. Even if the hallmarks of microbrewing—a small-scale, artisan approach to making beer—began as a backlash against the mass-produced system of large breweries, they relied on Maytag's early, intimate connections to the assembly-line world of the Maytag Company and the alchemy of intellectual curiosity, socioeconomic privilege, and risk tolerance with which his history equipped him.


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