Development and validation of 3‐CpG methylation prognostic signature based on different survival indicators for colorectal cancer

2021 ◽  
Author(s):  
Hao Huang ◽  
Lei Zhang ◽  
Jinming Fu ◽  
Tian Tian ◽  
Xinyan Liu ◽  
...  
2021 ◽  
Vol 9 (9) ◽  
pp. 747-747
Author(s):  
Junlan Feng ◽  
Qing Wei ◽  
Muqing Yang ◽  
Xiaodong Wang ◽  
Bin Liu ◽  
...  

2021 ◽  
Author(s):  
Xiao-Cheng Wang ◽  
Ya Liu ◽  
Fei-Wu Long ◽  
Liang-Ren Liu ◽  
Chuan-Wen Fan

Background: The relationship between long noncoding RNAs (lncRNAs) and the mRNA stemness index (mRNAsi) in colorectal cancer (CRC) is still unclear. Materials & methods: The mRNAsi, mRNAsi-related lncRNAs and their clinical significance were analyzed by bioinformatic approaches in The Cancer Genome Atlas (TCGA)-COREAD dataset. Results: mRNAsi was negatively related to pathological features but positively related to overall survival and recurrence-free survival in CRC. A five mRNAsi-related lncRNAs prognostic signature was further developed and showed independent prognostic factors related to overall survival in CRC patients, due to the five mRNAsi-related lncRNAs involved in several pathways of the cancer stem cells and malignant cancer cell phenotypes. Conclusion: The present study highlights the potential roles of mRNAsi-related lncRNAs as alternative prognostic markers.


2019 ◽  
Vol 9 ◽  
Author(s):  
Xiangyang Deng ◽  
Dongdong Lin ◽  
Bo Chen ◽  
Xiaojia Zhang ◽  
Xingxing Xu ◽  
...  

2019 ◽  
Vol 8 ◽  
Author(s):  
Xiao-Ping Liu ◽  
Xiao-Hong Yin ◽  
Xiang-Yu Meng ◽  
Xin-Hui Yan ◽  
Fan Wang ◽  
...  

2019 ◽  
Vol 8 (7) ◽  
pp. e1596715 ◽  
Author(s):  
Jianping Wu ◽  
Ying Zhao ◽  
Juanwen Zhang ◽  
Qianxia Wu ◽  
Weilin Wang

2020 ◽  
Vol 88 ◽  
pp. 106868
Author(s):  
Mengting Li ◽  
Haizhou Wang ◽  
Wenjie Li ◽  
Yanan Peng ◽  
Fei Xu ◽  
...  

2011 ◽  
Vol 29 (15_suppl) ◽  
pp. 3559-3559
Author(s):  
P. F. Lenehan ◽  
L. A. Boardman ◽  
D. W. Fry ◽  
E. R. Heyman ◽  
J. Ohrnberger ◽  
...  

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