The complex movement disorder of Kasabach-Merritt syndrome associated with a basal ganglia lesion

2012 ◽  
Vol 27 (4) ◽  
pp. 591-593
Author(s):  
Christos Ganos ◽  
Simone Zittel ◽  
Christian Gerloff ◽  
Alexander Münchau ◽  
Tobias Bäumer
Keyword(s):  
Basal Ganglia ◽  
Movement Disorder ◽  
Complex Movement

Charles David Marsden. 15 April 1938 — 29 September 1998

2012 ◽  
Vol 58 ◽  
pp. 203-228 ◽  
Author(s):  
Niall Quinn ◽  
John Rothwell ◽  
Peter Jenner
Keyword(s):  
Basal Ganglia ◽  
Movement Disorder ◽  
Communication Skills ◽  
Movement Disorders ◽  
Normal Function ◽  
Clinical Aspects ◽  
Publication Record ◽  
Research And Teaching ◽  
The Usa ◽  
Movement Disorder Society

David Marsden was the most outstanding UK clinical neuroscientist of his generation, making key discoveries in the neurophysiology, neurochemistry and clinical aspects of diseases of the basal ganglia, and their normal function. His legacies are the establishment, with Stanley Fahn in the USA, of movement disorders as a subspecialty within neurology, of the international Movement Disorder Society, and of the journal Movement Disorders ; his ex-students and fellows around the globe; and his research and teaching output embodied in his extraordinarily prolific publication record of more than 1360 papers, books and chapters, culminating in the posthumous completion and publication in December 2011 of Marsden’s book of movement disorders , a project he had started in 1984. All of these were achieved through the combination of his intellect and drive, his communication skills, and his forceful and charismatic personality.

scholarly journals Acute movement disorder with bilateral basal ganglia lesions in diabetic uremia

2011 ◽  
Vol 14 (3) ◽  
pp. 211 ◽  
Author(s):  
GurusidheshwarM Wali ◽  
RajendraV Mali ◽  
MallikarjunS Khanpet
Keyword(s):  
Basal Ganglia ◽  
Movement Disorder

P.378A complex movement disorder associated with myasthenic features: a novel phenotype caused by a homozygous NGLY1 mutation

2019 ◽  
Vol 29 ◽  
pp. S191-S192
Author(s):  
D. Jacquier ◽  
J. Good ◽  
B. Laubscher ◽  
D. Mercati ◽  
E. Roulet-Perez ◽  
...  
Keyword(s):  
Movement Disorder ◽  
Complex Movement

scholarly journals A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Muhammed Emin Özcan ◽  
Meriç Adil Altınöz ◽  
Hasan Hüseyin Karadeli ◽  
Talip Asil ◽  
Abdulkadir Koçer
Keyword(s):  
Movement Disorder ◽  
Antiphospholipid Antibodies ◽  
Sudden Onset ◽  
Systemic Lupus ◽  
Rare Presentation ◽  
Glycoprotein I ◽  
Neuronal Stimulation ◽  
Caucasian Female ◽  
Complex Movement

Complex movement disorder is a relatively rare presentation of neurolupus. Antiphospholipid antibodies are associated with movement disorders likely via aberrant neuronal stimulation. Antiribosomal P antibodies have been previously associated with neuropsychiatric disorders but their correlation with movement disorder was not previously established. Our case report involves a 17-year-old Caucasian female patient positive for only antiribosomal P antibody and lupus anticoagulant who presented with a sudden onset of complex movement disorder. After complete cessation of physical signs with olanzapine, anticardiolipin and anti-β2 glycoprotein I antibodies became positive which indicates a likely discordance between movement disorder and antiphospholipid antibodies. This also indicates a potential causal role of antiribosomal P antibodies in inducing movement disorder.

Basal ganglia neural mechanisms of natural movement sequences

2004 ◽  
Vol 82 (8-9) ◽  
pp. 732-739 ◽  
Author(s):  
J Wayne Aldridge ◽  
Kent C Berridge ◽  
Alyssa R Rosen
Keyword(s):  
Basal Ganglia ◽  
Neural Mechanisms ◽  
Sequential Patterns ◽  
Striatal Neurons ◽  
Warm Up ◽  
Movement Sequences ◽  
Natural Movement ◽  
Baseline Levels ◽  
Instinctive Behavior ◽  
Complex Movement

Natural rodent grooming and other instinctive behavior serves as a natural model of complex movement sequences. Rodent grooming has syntactic (rule-driven) sequences and more random movement patterns. Both incorporate the same movements—only the serial structure differs. Recordings of neural activity in the dorsolateral striatum and the substantia nigra pars reticulata indicate preferential activation during syntactic sequences over more random sequences. Neurons that are responsive during syntactic grooming sequences are often unresponsive or have reverse activation profiles during kinematically similar movements that occur in flexible or random grooming sequences. Few neurons could be categorized as strictly movement related—instead they were activated only in the context of particular sequential patterns of movements. Particular sequential patterns included "syntactic chain" grooming sequences of paw, head, and body movements and also "warm-up" sequences, which consist of head and body/limb movements that precede locomotion after a period of quiet resting (Golani 1992). Activation during warm-up was less intense and less frequent than during grooming sequences, but both sequences activated neurons above baseline levels, and the same neurons sometimes responded to both sequences. The fact that striatal neurons code 2 natural sequences which are made up of different constituent movements suggests that the basal ganglia may have a generalized role in sequence control. The basal ganglia are modulated by the context of the sequence and may play an executive function in the complex natural patterns of sequenced behaviour.Key words: movement, basal ganglia, striatum, movement sequences, sensorimotor behaviour.

scholarly journals Complex movement disorder in an elderly patient and the chimera effect

2012 ◽  
Vol 70 (5) ◽  
pp. 382-383
Author(s):  
Marco A. T. Utiumi ◽  
Renato P. Munhoz ◽  
Caroline Cartaxo ◽  
Hélio A. G. Teive
Keyword(s):  
Elderly Patient ◽  
Movement Disorder ◽  
Complex Movement

scholarly journals Mutations in the mitochondrial cysteinyl-tRNA synthase gene,CARS2,lead to a severe epileptic encephalopathy and complex movement disorder

2015 ◽  
Vol 52 (8) ◽  
pp. 532-540 ◽  
Author(s):  
Curtis R Coughlin ◽  
Gunter H Scharer ◽  
Marisa W Friederich ◽  
Hung-Chun Yu ◽  
Elizabeth A Geiger ◽  
...  
Keyword(s):  
Movement Disorder ◽  
Epileptic Encephalopathy ◽  
Complex Movement
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