scholarly journals Effects of COVID ‐19 on Parkinson's Disease Clinical Features: A Community‐Based Case‐Control Study

2020 ◽  
Vol 35 (8) ◽  
pp. 1287-1292 ◽  
Author(s):  
Roberto Cilia ◽  
Salvatore Bonvegna ◽  
Giulia Straccia ◽  
Nico Golfrè Andreasi ◽  
Antonio E. Elia ◽  
...  
2010 ◽  
Vol 25 (15) ◽  
pp. 2587-2594 ◽  
Author(s):  
Michael Y. Shino ◽  
Valerie McGuire ◽  
Stephen K. Van Den Eeden ◽  
Caroline M. Tanner ◽  
Rita Popat ◽  
...  

2019 ◽  
Vol 19 (5-6) ◽  
pp. 211-217
Author(s):  
Muhammad Tufail

Background: Parkinson’s disease (PD) is one of the most common neurological disorders that mostly affect aged individuals. The common symptoms of PD are rest tremor, bradykinesia, and rigidity. Objectives: The present study was devised to find out the clinical features and risk factors associated with PD in a population of Khyber Pakhtunkhwa. Methods:A total of 600 PD patients and 1,200 control individuals took part in this study. The participants filled out a standard questionnaire. Results: This study found a significant association between PD and exposure to pesticides (p < 0.0001) and doing work on farms (p < 0.0001). The use of aldrin was significantly associated with PD (p < 0.0001). Furthermore, we also found that PD status was associated with individuals who have a history of depression, hypertension, head injury, and Alzheimer’s disease. This study also showed that the PD rate was lower in those who were using tobacco products. Conclusion: In this case-control study, we revealed some environmental and medical conditions that are linked with PD. To control the disease, we must minimize exposure to pesticides, and the government and scientific community should play their role.


2012 ◽  
Vol 7 (1) ◽  
pp. 172
Author(s):  
E. Cereda ◽  
M. Barichella ◽  
E. Cassani ◽  
R. Caccialanza ◽  
G. Pezzoli

Author(s):  
Hamdy N. El-Tallawy ◽  
Tahia H. Saleem ◽  
Wafaa M. Farghaly ◽  
Heba Mohamed Saad Eldien ◽  
Ashraf Khodaery ◽  
...  

Abstract Background Parkinson’s disease is one of the neurodegenerative disorders that is caused by genetic and environmental factors or interaction between them. Solute carrier family 41 member 1 within the PARK16 locus has been reported to be associated with Parkinson’s disease. Cognitive impairment is one of the non-motor symptoms that is considered a challenge in Parkinson’s disease patients. This study aimed to investigate the association of rs11240569 polymorphism; a synonymous coding variant in SLC41A1 in Parkinson’s disease patients in addition to the assessment of cognitive impairment in those patients. Results In a case -control study, rs11240569 single nucleotide polymorphisms in SLC41A1, genes were genotyped in 48 Parkinson’s disease patients and 48 controls. Motor and non-motor performance in Parkinson's disease patients were assessed by using the Movement Disorder Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS). The genotype and allele frequencies were compared between the two groups and revealed no significant differences between case and control groups for rs11240569 in SLC41A1 gene with P value .523 and .54, respectively. Cognition was evaluated and showed the mean ± standard deviation (SD) of WAIS score of PD patients 80.4 ± 9.13 and the range was from 61 to 105, in addition to MMSE that showed mean ± SD 21.96 ± 3.8. Conclusion Genetic testing of the present study showed that rs11240569 polymorphism of SLC41A1 gene has no significant differences in distributions of alleles and genotypes between cases and control group, in addition to cognitive impairment that is present in a large proportion of PD patients and in addition to the strong correlation between cognitive impairment and motor and non-motor symptoms progression.


2007 ◽  
Vol 13 ◽  
pp. S40-S41
Author(s):  
V. Pieri ◽  
M. Vaillant ◽  
S. Blyth ◽  
G. Hipp ◽  
N.J. Diederich

2020 ◽  
Vol 79 ◽  
pp. e38
Author(s):  
C.A. Soto-Rincón ◽  
S.A. Castillo Torres ◽  
D.G. Marítnez-Roque ◽  
J. Duarte-Bravo ◽  
S. España-Pérez ◽  
...  

2004 ◽  
Vol 19 (7) ◽  
pp. 807-811 ◽  
Author(s):  
Marco D'Amelio ◽  
Paolo Ragonese ◽  
Letterio Morgante ◽  
Antonio Epifanio ◽  
Graziella Callari ◽  
...  

2013 ◽  
Vol 333 ◽  
pp. e612
Author(s):  
L. Sellitti ◽  
M. Bigoni ◽  
L. Priano ◽  
G. Albani ◽  
R. Picconi ◽  
...  

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