Alveolar oxygen partial pressure and oxygen depletion rate mapping in rats using3He ventilation imaging

2007 ◽  
Vol 57 (2) ◽  
pp. 423-430 ◽  
Author(s):  
Katarzyna Cieślar ◽  
Vasile Stupar ◽  
Emmanuelle Canet-Soulas ◽  
Sophie Gaillard ◽  
Yannick Crémillieux
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Oxygen Depletion ◽  
Ventilation Imaging ◽  
Depletion Rate ◽  
Alveolar Oxygen

Effect of varying alveolar oxygen partial pressure on diffusing capacity for nitric oxide and carbon monoxide, membrane diffusing capacity and lung capillary blood volume

1991 ◽  
Vol 81 (6) ◽  
pp. 759-765 ◽  
Author(s):  
C. D. R. Borland ◽  
Y. Cox
Keyword(s):  
Nitric Oxide ◽  
Carbon Monoxide ◽  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Diffusing Capacity ◽  
Pulmonary Capillary ◽  
Capillary Blood Volume ◽  
Novel Method ◽  
The Mean ◽  
Alveolar Oxygen

1. To examine the effect of varying oxygen partial pressure (Pao2) on nitric oxide (DLNO) and carbon monoxide (DLCO) diffusing capacity (transfer factor), 10 subjects performed combined DLCO/DLNO measurements with the inspired mixture made up with three different oxygen concentrations (25%, 18% and 15%) to give Pao2 values of 12–20 kPa. 2. A novel method is described for calculating membrane diffusing capacity (DM) and pulmonary capillary volume (Qc) from DLNO and DLCO. 3. The mean DMCO was 52.89 mmol min−1 kPa−1 and Qc was 0.056 litre. Reducing Pao2 from 20 to 12 kPa resulted in an increase in DLCO = −0.124 (O2%) + 11.67 (P < 0.001) and a fall in DLNO = 0.538 (O2%) + 32.01 (P < 0.001) and a fall in DLNO/DLCO = 0.107 (O2%) + 2.52 (P < 0.001). DM (P = 0.59) and Qc (P = 0.64) also tended to fall with falling Pao2. 4. It appears more likely that the minor reduction in DLNO that we have observed with falling Pao2 is due to diffusion rather than reaction limitation.

Arterial-alveolar oxygen partial pressure ratio

1986 ◽  
Vol 14 (2) ◽  
pp. 153-154 ◽  
Author(s):  
JEAN-PAUL VIALE ◽  
CARLISLE J. PERCIVAL ◽  
GUY ANNAT ◽  
BERNARD ROUSSELET ◽  
JEAN MOTIN
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Pressure Ratio ◽  
Alveolar Oxygen ◽  
Partial Pressure Ratio

Stability of the arterial/alveolar oxygen partial pressure ratio

1979 ◽  
Vol 7 (6) ◽  
pp. 267-272 ◽  
Author(s):  
ROBERT GILBERT ◽  
J. H. AUCHINCLOSS ◽  
MITCHELL KUPPINGER ◽  
M. VARKEY THOMAS
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Pressure Ratio ◽  
Alveolar Oxygen ◽  
Partial Pressure Ratio

scholarly journals Measurement of alveolar oxygen partial pressure in the rat lung using Carr-Purcell-Meiboom-Gill spin-spin relaxation times of hyperpolarized 3 He and 129 Xe at 74 mT

2010 ◽  
Vol 64 (5) ◽  
pp. 1484-1490 ◽  
Author(s):  
Ryan J. Kraayvanger ◽  
Christopher P. Bidinosti ◽  
William Dominguez-Viqueira ◽  
Juan Parra-Robles ◽  
Matthew Fox ◽  
...  
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Spin Relaxation ◽  
Relaxation Times ◽  
Rat Lung ◽  
Alveolar Oxygen

Effect of oxygen tension on killing ofEscherichia coliby bovine polymorphonuclear neutrophil leucocytesin vitro

1995 ◽  
Vol 62 (2) ◽  
pp. 331-338 ◽  
Author(s):  
John J. Goldberg ◽  
J. Woodrow Pankey ◽  
Ioannis Politis ◽  
Boris Zavizion ◽  
A. John Bramley
Keyword(s):  
Escherichia Coli ◽  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Oxygen Tension ◽  
Oxygen Depletion ◽  
Polymorphonuclear Neutrophil ◽  
Batch Fermenter ◽  
Specific Association ◽  
Effect Of Oxygen

SUMMARYA batch fermenter modified to simulate the physical conditions of an inflamedv. uninflamed mammary gland was utilized to evaluate the effect of oxygen tension on killing ofEscherichia coliP4 by bovine polymorphonuclear neutrophil leucocytes. Leucocytosis was simulatedin vitro4 h after inoculation withEscherichia coliby adding bovine neutrophils isolated from peripheral blood to the culture medium. Experiments were conducted at 39°C in UHT treated milk. At micro-aerophilic oxygen tension (oxygen partial pressure, 3·11kPa), bacterial numbers declined during the first hour following addition of the neutrophils. Oxygen tension declined rapidly following PMN addition. Once oxygen was depleted, neutrophil activity was presumably diminished andEsch. colinumbers began to increase. Under anaerobic conditions (oxygen partial pressure, 0·17kPa), no reduction in population was observed. Photomicrographs taken at the time of neutrophil addition and at subsequent time intervals demonstrated a specific association between neutrophils and the pathogen. Subsequent lysis of neutrophils associated withEsch. coligrowth was seen coincident with oxygen depletion.

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