scholarly journals Modeling of Look-Locker estimates of the magnetic resonance imaging estimate of longitudinal relaxation rate in tissue after contrast administration

2011 ◽  
Vol 66 (5) ◽  
pp. 1432-1444 ◽  
Author(s):  
Ramesh Paudyal ◽  
Hassan Bagher-Ebadian ◽  
Tavarekere N. Nagaraja ◽  
Joseph D. Fenstermacher ◽  
James. R. Ewing

2021 ◽  
Vol 7 (4) ◽  
pp. 205521732110479
Author(s):  
Kianush Karimian-Jazi ◽  
Ulf Neuberger ◽  
Katharina Schregel ◽  
Gianluca Brugnara ◽  
Martin Bendszus ◽  
...  

Background Magnetic resonance imaging is essential for monitoring people with multiple sclerosis, but the diagnostic value of gadolinium contrast administration in spine magnetic resonance imaging is unclear. Objective To assess the diagnostic value of gadolinium contrast administration in spine magnetic resonance imaging follow-up examinations and identify imaging markers correlating with lesion enhancement. Methods A total of 65 multiple sclerosis patients with at least 2 spinal magnetic resonance imaging follow-up examinations were included. Spine magnetic resonance imaging was performed at 3 Tesla with a standardized protocol (sagittal and axial T2-weighted turbo spin echo and T1-weighted post-contrast sequences). T2 lesion load and enhancing lesions were assessed by two independent neuroradiologists for lesion size, localization, and T2 signal ratio (T2 signallesion/T2 signalnormal appearing spinal cord). Results A total of 68 new spinal T2 lesions and 20 new contrast-enhancing lesions developed during follow-up. All enhancing lesions had a discernable correlate as a new T2 lesion. Lesion enhancement correlated with a higher T2 signal ratio compared to non-enhancing lesions (T2 signal ratio: 2.0 ± 0.4 vs. 1.4 ± 0.2, **** p < 0.001). Receiver operating characteristics analysis showed an optimal cutoff value of signal ratio 1.78 to predict lesion enhancement (82% sensitivity and 97% specificity). Conclusion Gadolinium contrast administration is dispensable in follow-up spine magnetic resonance imaging if no new T2 lesions are present. Probability of enhancement correlates with the T2 signal ratio.



2020 ◽  
pp. 2000579
Author(s):  
Roland Balbierer ◽  
Philipp Seegert ◽  
Sabrina Herberger ◽  
Thomas Wetzel ◽  
Hermann Nirschl ◽  
...  


2018 ◽  
Vol 6 (8) ◽  
pp. 2209-2218 ◽  
Author(s):  
Siqi Wang ◽  
Wenzhi Ren ◽  
Jianhua Wang ◽  
Zhenqi Jiang ◽  
Madiha Saeed ◽  
...  

New type of black TiO2 nanoprobes with high long relaxation rate and significant targeting capability were prepared for magnetic resonance imaging guided photothermal therapy in pancreatic stem-like cells.



2001 ◽  
Vol 41 (supplement) ◽  
pp. S186
Author(s):  
S. Matsushima ◽  
S. Era ◽  
M. Sogami ◽  
Y. Kinosada ◽  
H. Oosaki ◽  
...  




Sign in / Sign up

Export Citation Format

Share Document