scholarly journals Visceral adiposity elevates the risk of critical condition in COVID‐19: A systematic review and meta‐analysis

Obesity ◽  
2020 ◽  
Author(s):  
Mária Földi ◽  
Nelli Farkas ◽  
Szabolcs Kiss ◽  
Fanni Dembrovszky ◽  
Zsolt Szakács ◽  
...  
Keyword(s):  
Systematic Review ◽  
Critical Condition ◽  
Meta Analysis ◽  
Visceral Adiposity

scholarly journals Procalcitonin Has Good Accuracy for Prognosis of Critical Condition and Mortality in COVID-19: A Diagnostic Test Accuracy Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Mohammad Erfan Zare ◽  
Yanzhong Wang ◽  
Atefeh Nasir Kansestani ◽  
Afshin Almasi ◽  
Jun Zhang
Keyword(s):  
Systematic Review ◽  
Critical Condition ◽  
Good Accuracy ◽  
Prognostic Biomarker ◽  
Meta Analysis ◽  
Inflammatory Biomarkers ◽  
Test Accuracy ◽  
Cell Counts ◽  
Blood Cell Counts ◽  
White Blood Cell Counts

Several reports have determined that changes in white blood cell counts and inflammatory biomarkers are related to disease outcome of coronavirus disease 2019 (COVID-19) and they can be utilized as prognostic biomarkers. For introducing a factor as a diagnostic/prognostic biomarker, diagnostic test accuracy (DTA) systematic review and meta-analysis are recommended. For the first time, we aimed to determine the accuracies of white blood cell counts and inflammatory biomarkers for prognosis of COVID-19 patient’s outcome by a DTA meta-analysis. Until August 24, 2020, we searched Web of Sciences, Scopus, and MEDLINE/PubMed databases to achieve related papers. Summary points and lines of included studies were calculated from 2×2 tables by bivariate/hierarchical models. Critical condition and mortality were considered as outcomes. A total of 13387 patients from 28 studies were included in this study. Six biomarkers containing leukocytosis, neutrophilia, lymphopenia, increased level of C-reactive protein, procalcitonin (PCT), and ferritin met the inclusion criteria. Analysis of the area under the curve (AUCHSROC) indicated that the PCT was the only applicable prognostic biomarker for critical condition and mortality (AUCHSROC=0.80 for both conditions). Pooled-diagnostic odds ratios were 6.78 (95% CI, 3.65-12.61) for prognosis of critical condition and 13.21 (95% CI, 3.95-44.19) for mortality. Other biomarkers had insufficient accuracies for both conditions (AUCHSROC< 0.80). Among evaluated biomarkers, only PCT has good accuracy for the prognosis of both critical condition and mortality in COVID-19 and it can be considered as a single prognostic biomarker for poor outcomes. Also, PCT has more accuracy for the prognosis of mortality in comparison to critical conditions.

scholarly journals Obesity is a risk factor for developing critical condition in COVID‐19 patients: A systematic review and meta‐analysis

2020 ◽  
Vol 21 (10) ◽  
Author(s):  
Mária Földi ◽  
Nelli Farkas ◽  
Szabolcs Kiss ◽  
Noémi Zádori ◽  
Szilárd Váncsa ◽  
...  
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Critical Condition ◽  
Meta Analysis

scholarly journals The Accuracy of Visceral Adiposity Index for the Screening of Metabolic Syndrome: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Moniba Bijari ◽  
Sara Jangjoo ◽  
Nima Emami ◽  
Sara Raji ◽  
Mahdi Mottaghi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Metabolic Syndrome ◽  
Low Cost ◽  
Meta Analysis ◽  
Fat Distribution ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Test Accuracy ◽  
Operating Characteristics ◽  
Adiposity Index

Background and Aims. Visceral adiposity index (VAI) is a novel marker of fat distribution and function which incorporates both anthropometric and laboratory measures. Recently, several studies have suggested VAI as a screening tool for metabolic syndrome (MetS). Here, we aimed to consolidate the results of these studies by performing a systematic review and meta-analysis. Methods and Results. We searched PubMed and EMBASE online databases for eligible studies that investigated the association of VAI and MetS. After reviewing 294 records, we included 33 eligible papers with a sum of 20516 MetS and 53242 healthy participants. The risk of bias in the included studies was assessed, and the relevant data was extracted. All included studies reported a significant association between VAI and MetS screening, but were highly heterogeneous in their reported effects. We pooled the diagnostic test accuracy metrics of VAI for MetS screening and showed that it has a moderate-to-high accuracy with an area under the summary receiver operating characteristics curve of 0.847, a pooled sensitivity of 78%, and a pooled specificity of 79%. Besides, we pooled the difference in means of VAI between patients with MetS and healthy controls, revealing that VAI was 2.15 units higher in MetS patients. Conclusions. VAI is an accurate, low-cost, and widely available screening marker for MetS. However, further studies are needed to evaluate its applicability in clinical practice, determine an optimal cut-off, and identify populations that would benefit the most from it.

The effects of low-ratio n-6/n-3 PUFA on biomarkers of inflammation: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Yali Wei ◽  
Yan Meng ◽  
Na Li ◽  
Qian Wang ◽  
Liyong Chen
Keyword(s):  
Systematic Review ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Chain Polyunsaturated Fatty Acid ◽  
Inflammation Markers ◽  
Pufa Supplementation ◽  
Long Chain

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.

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