scholarly journals Mesoporous Silica Nanoparticles Functionalized with Amino Groups for Biomedical Applications

ChemistryOpen ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1251-1259
Author(s):  
Bianca Martins Estevão ◽  
Ivana Miletto ◽  
Noboru Hioka ◽  
Leonardo Marchese ◽  
Enrica Gianotti
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Biomedical Applications ◽  
Mesoporous Silica Nanoparticles ◽  
Amino Groups

Functionalized mesoporous silica nanoparticles and biomedical applications

2019 ◽  
Vol 99 ◽  
pp. 631-656 ◽  
Author(s):  
Thai Thanh Hoang Thi ◽  
Van Du Cao ◽  
Thi Nhu Quynh Nguyen ◽  
Duc Thuan Hoang ◽  
Van Cuong Ngo ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Biomedical Applications ◽  
Mesoporous Silica Nanoparticles ◽  
Functionalized Mesoporous Silica

Mesoporous Silica Nanoparticles as a Prospective and Promising Approach for Drug Delivery and Biomedical Applications

2019 ◽  
Vol 19 (4) ◽  
pp. 285-295 ◽  
Author(s):  
Xiaohui Pu ◽  
Jia Li ◽  
Peng Qiao ◽  
Mengmeng Li ◽  
Haiyan Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Biomedical Applications ◽  
Mesoporous Silica Nanoparticles ◽  
Release Kinetics ◽  
Drug Loading ◽  
Synthetic Methods ◽  
Pubmed Database ◽  
Modified Surface

Background: With the development of nanotechnology, nanocarrier has widely been applied in such fields as drug delivery, diagnostic and medical imaging and engineering in recent years. Among all of the available nanocarriers, mesoporous silica nanoparticles (MSNs) have become a hot issue because of their unique properties, such as large surface area and voidage, tunable drug loading capacity and release kinetics, good biosafety and easily modified surface. Objective: We described the most recent progress in silica-assisted drug delivery and biomedical applications according to different types of Cargo in order to allow researchers to quickly learn about the advance in this field. Methods: Information has been collected from the recently published literature available mainly through Title or Abstract search in SpringerLink and PubMed database. Special emphasis is on the literature available during 2008-2017. Results: In this review, the major research advances of MSNs on the drug delivery and biomedical applications were summarized. The significant advantages of MSNs have also been listed. It was found that the several significant challenges need to be addressed and investigated to further advance the applications of these structurally defined nanomaterials. Conclusion: Through approaching this review, the researchers can be aware of many new synthetic methods, smart designs proposed in the recent year and remaining questions of MSNs at present.

scholarly journals A Toolbox for the Synthesis of Multifunctionalized Mesoporous Silica Nanoparticles for Biomedical Applications

ACS Omega ◽  
2018 ◽  
Vol 3 (12) ◽  
pp. 17496-17510 ◽  
Author(s):  
Cornelia von Baeckmann ◽  
Rémy Guillet-Nicolas ◽  
Damien Renfer ◽  
Hanspeter Kählig ◽  
Freddy Kleitz
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Biomedical Applications ◽  
Mesoporous Silica Nanoparticles

scholarly journals Mesoporous silica nanoparticles for drug delivery—Recent advances

2019 ◽  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Targeted Delivery ◽  
Biomedical Applications ◽  
Mesoporous Silica Nanoparticles ◽  
Mesoporous Structure ◽  
Pharmaceutical Ingredients ◽  
Recent Advances ◽  
Controllable Release

Mesoporous silica nanoparticles (MSNs) have been attracting great attention for the potential biomedical applications in the last decades. Due to the unique properties, such as tunable mesoporous structure, huge surface area, large pore volume, as well as the functional ability of surface, MSNs exhibit high loading capacity for therapeutic active pharmaceutical ingredients (APIs) and controllable release behavior. In this review, the applications of MSNs in pharmaceutics improving the bioavailability, reducing toxicity of loaded drugs, increasing cellular targeted delivery ability and recent advances in drug delivery are summarized.

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