Semi-preparative isolation and purification of phenolic compounds from Achyrocline satureioides (Lam) D.C. by high-performance counter-current chromatography

2018 ◽  
Vol 30 (2) ◽  
pp. 182-192 ◽  
Author(s):  
Sara Elis Bianchi ◽  
Samuel Kaiser ◽  
Vanessa Pittol ◽  
Eduarda Doneda ◽  
Kellen Cristhinia Borges De Souza ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
High Performance ◽  
Isolation And Purification ◽  
Performance Counter ◽  
Preparative Isolation ◽  
Achyrocline Satureioides ◽  
Counter Current

scholarly journals Phenolic compounds of Iris adriatica and their antimycobacterial effects

2019 ◽  
Vol 69 (4) ◽  
pp. 673-681 ◽  
Author(s):  
Sandra Ochensberger ◽  
Fabian Alperth ◽  
Božena Mitić ◽  
Olaf Kunert ◽  
Stefanie Mayer ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Ethidium Bromide ◽  
Mycobacterium Smegmatis ◽  
High Performance ◽  
Pharmacological Activities ◽  
Performance Counter ◽  
Bioassay Guided Fractionation ◽  
Counter Current

Abstract Little is known about the pharmacological activities of Iris adriatica (Iridaceae), a plant endemic to Dalmatia (Croatia). We therefore performed a bioassay-guided fractionation including high-performance counter current chromatography (HPCCC) and antibacterial tests using Mycobacterium smegmatis mc2 155. One obtained fraction was found to be antimycobacterially active with a MIC of 64 mg L−1. Furthermore, fractions were tested for resistance modulatory effects using ethidium bromide as substrate. We were able to identify the pure isoflavonic compounds irigenin and irilone and a fraction containing mainly benzophenone 2,4,6-trihydroxy-4-methoxy-benzophenone, responsible for the resistance-modulatory activity of this plant.

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