A viewpoint on population analyses

<div>Population analyses based on point charge approximations accurately estimating the equilibrium dipole moment will systematically fail when predicting infrared intensities of out-of-plane vibrations of planar molecules, whereas models based on both charges and dipoles will always succeed. It is not a matter of how the model is devised, but on its number of degrees of freedom. Population analyses based on point charges are very limited in terms of the amount of meaningful chemical information they provide, whereas models employing both atomic charges and atomic dipoles should be preferred for molecular distortions. A good model should be able to correctly describe not only static, equilibrium structures but also distorted geometries in order to correctly assess information from vibrating molecules. The limitations of point charge models also hold for distortions much larger than those encountered vibrationally.</div>

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Development of EPIC-PCR Markers for Lutjanus purpureus (Lutjanidae-Perciformes) and their Potential Applicability in Population Analyses

Anais da Academia Brasileira de Ciências ◽

10.1590/0001-3765201720150476 ◽

2017 ◽

Vol 89 (3 suppl) ◽

pp. 2095-2100 ◽

Cited By ~ 1

Author(s):

RAIMUNDO DA SILVA ◽

DANILLO SILVA ◽

IVANA VENEZA ◽

IRACILDA SAMPAIO ◽

HORACIO SCHNEIDER ◽

...

Keyword(s):

Pcr Markers ◽

Population Analyses ◽

Potential Applicability

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Distinct roles of visual, parietal, and frontal motor cortices in memory-guided sensorimotor decisions

eLife ◽

10.7554/elife.13764 ◽

2016 ◽

Vol 5 ◽

Cited By ~ 97

Author(s):

Michael J Goard ◽

Gerald N Pho ◽

Jonathan Woodson ◽

Mriganka Sur

Keyword(s):

Calcium Imaging ◽

Large Scale ◽

Behavioral Choice ◽

Population Analyses ◽

Delay Response ◽

Sensory Features ◽

Posterior Parietal ◽

Stimulus Identity ◽

Motor Actions

Mapping specific sensory features to future motor actions is a crucial capability of mammalian nervous systems. We investigated the role of visual (V1), posterior parietal (PPC), and frontal motor (fMC) cortices for sensorimotor mapping in mice during performance of a memory-guided visual discrimination task. Large-scale calcium imaging revealed that V1, PPC, and fMC neurons exhibited heterogeneous responses spanning all task epochs (stimulus, delay, response). Population analyses demonstrated unique encoding of stimulus identity and behavioral choice information across regions, with V1 encoding stimulus, fMC encoding choice even early in the trial, and PPC multiplexing the two variables. Optogenetic inhibition during behavior revealed that all regions were necessary during the stimulus epoch, but only fMC was required during the delay and response epochs. Stimulus identity can thus be rapidly transformed into behavioral choice, requiring V1, PPC, and fMC during the transformation period, but only fMC for maintaining the choice in memory prior to execution.

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Population Analyses Based on Ionic Partition of Overlap Distributions

Quantum Systems in Physics, Chemistry, and Biology - Progress in Theoretical Chemistry and Physics ◽

10.1007/978-3-319-50255-7_4 ◽

2017 ◽

pp. 65-74

Author(s):

Ya Kun Chen ◽

Yan Alexander Wang

Keyword(s):

Population Analyses

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Impact of mutations in hVISA isolates on decreased susceptibility to vancomycin, through population analyses profile – area under curve (PAP-AUC)

Diagnostic Microbiology and Infectious Disease ◽

10.1016/j.diagmicrobio.2019.06.006 ◽

2019 ◽

Vol 95 (3) ◽

pp. 114854 ◽

Cited By ~ 1

Author(s):

A.C.O. Silveira ◽

J. Caierão ◽

C.I. Silva ◽

E.K. Anzai ◽

J.A. McCulloch ◽

...

Keyword(s):

Area Under Curve ◽

Population Analyses ◽

Profile Area

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The astrophysical odds of GW151216

Monthly Notices of the Royal Astronomical Society ◽

10.1093/mnras/staa2332 ◽

2020 ◽

Vol 498 (2) ◽

pp. 1905-1910 ◽

Cited By ~ 1

Author(s):

Gregory Ashton ◽

Eric Thrane

Keyword(s):

Black Holes ◽

Black Hole ◽

Gravitational Wave ◽

Bayesian Method ◽

Massive Stars ◽

Stellar Mass ◽

Population Analyses ◽

Wave Detection ◽

Binary Black Hole ◽

Bona Fide

ABSTRACT The gravitational-wave candidate GW151216 is a proposed binary black hole event from the first observing run of the Advanced LIGO detectors. Not identified as a bona fide signal by the LIGO–Virgo collaboration, there is disagreement as to its authenticity, which is quantified by pastro, the probability that the event is astrophysical in origin. Previous estimates of pastro from different groups range from 0.18 to 0.71, making it unclear whether this event should be included in population analyses, which typically require pastro > 0.5. Whether GW151216 is an astrophysical signal or not has implications for the population properties of stellar-mass black holes and hence the evolution of massive stars. Using the astrophysical odds, a Bayesian method that uses the signal coherence between detectors and a parametrized model of non-astrophysical detector noise, we find that pastro = 0.03, suggesting that GW151216 is unlikely to be a genuine signal. We also analyse GW150914 (the first gravitational-wave detection) and GW151012 (initially considered to be an ambiguous detection) and find pastro values of 1 and 0.997, respectively. We argue that the astrophysical odds presented here improve upon traditional methods for distinguishing signals from noise.

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Genomic and Population Analyses of the Mating Type Loci in Coccidioides Species Reveal Evidence for Sexual Reproduction and Gene Acquisition

Eukaryotic Cell ◽

10.1128/ec.00117-07 ◽

2007 ◽

Vol 6 (7) ◽

pp. 1189-1199 ◽

Cited By ~ 65

Author(s):

M. Alejandra Mandel ◽

Bridget M. Barker ◽

Scott Kroken ◽

Steven D. Rounsley ◽

Marc J. Orbach

Keyword(s):

Sexual Reproduction ◽

Mating Type ◽

Mating Types ◽

Coccidioides Immitis ◽

Genome Sequences ◽

Valley Fever ◽

Population Analyses ◽

Gene Acquisition ◽

Close Proximity

ABSTRACT Coccidioides species, the fungi responsible for the valley fever disease, are known to reproduce asexually through the production of arthroconidia that are the infectious propagules. The possible role of sexual reproduction in the survival and dispersal of these pathogens is unexplored. To determine the potential for mating of Coccidioides, we analyzed genome sequences and identified mating type loci characteristic of heterothallic ascomycetes. Coccidioides strains contain either a MAT1-1 or a MAT1-2 idiomorph, which is 8.1 or 9 kb in length, respectively, the longest reported for any ascomycete species. These idiomorphs contain four or five genes, respectively, more than are present in the MAT loci of most ascomycetes. Along with their cDNA structures, we determined that all genes in the MAT loci are transcribed. Two genes frequently found in common sequences flanking MAT idiomorphs, APN2 and COX13, are within the MAT loci in Coccidioides, but the MAT1-1 and MAT1-2 copies have diverged dramatically from each other. Data indicate that the acquisition of these genes in the MAT loci occurred prior to the separation of Coccidioides from Uncinocarpus reesii. An analysis of 436 Coccidioides isolates from patients and the environment indicates that in both Coccidioides immitis and C. posadasii, there is a 1:1 distribution of MAT loci, as would be expected for sexually reproducing species. In addition, an analysis of isolates obtained from 11 soil samples demonstrated that at three sampling sites, strains of both mating types were present, indicating that compatible strains were in close proximity in the environment.

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