Dissociation of gas-phase dimeric complexes of lactic acid and transition-metal ions formed under electrospray ionization conditions; the role of reduction of the metal ion

Ferric uptake regulation protein is a repressor protein which binds an AT rich region of DNA (the iron box). Fur binds as a dimer in a helix turn helix mode and it is activated by iron(II) and other transition metal ions at elevated concentrations. Each transition metal ion induces certain conformational changes to aid the Fur binding, both the N-terminal and C-terminal domains take part in binding to DNA in addition to His 88 and His 86. The process is discussed in view of experimental reports. Fe(II), Mn(II) and Co(II) activate Fur to bind DNA but Zinc plays a structural role and does not activate Fur to bind DNA.

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The Role of Divalent Transition Metal Ions in the Binding of Fur Dimer to DNA: Binding of Mn2+ and Co2+ to EC Fur dimer-DNA Complex

10.20944/preprints202011.0146.v3 ◽

2020 ◽

Author(s):

Mazen Hamed ◽

Salih Jabour

Keyword(s):

Dna Binding ◽

Transition Metal ◽

Metal Ions ◽

Conformational Changes ◽

Metal Ion ◽

Transition Metal Ions ◽

Rich Region ◽

Repressor Protein ◽

Dna Complex

Ferric uptake regulation protein is a repressor protein which binds an AT rich region of DNA (the iron box). Fur binds as a dimer in a helix turn helix mode and it is activated by iron(II) and other transition metal ions at elevated concentrations. Each transition metal ion induces certain conformational changes to aid the Fur binding, both the N-terminal and C-terminal domains take part in binding to DNA in addition to His 88 and His 86. The process is discussed in view of experimental reports. Fe(II), Mn(II) and Co(II) activate Fur to bind DNA but Zinc plays a structural role and does not activate Fur to bind DNA.

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The Role of Divalent Transition Metal Ions in the Binding of Fur Dimer to DNA: Binding of Mn2+ and Co2+ to EC Fur dimer-DNA Complex

10.20944/preprints202011.0146.v2 ◽

2020 ◽

Author(s):

Mazen Hamed ◽

Salih Jabour

Keyword(s):

Dna Binding ◽

Transition Metal ◽

Metal Ions ◽

Conformational Changes ◽

Metal Ion ◽

Transition Metal Ions ◽

Rich Region ◽

Repressor Protein ◽

Dna Complex

Ferric uptake regulation protein is a repressor protein which binds an AT rich region of DNA (the iron box). Fur binds as a dimer in a helix turn helix mode and it is activated by iron(II) and other transition metal ions at elevated concentrations. Each transition metal ion induces certain conformational changes to aid the Fur binding, both the N-terminal and C-terminal domains take part in binding to DNA in addition to His 88 and His 86. The process is discussed in view of experimental reports. Fe(II), Mn(II) and Co(II) activate Fur to bind DNA but Zinc plays a structural role and does not activate Fur to bind DNA.

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Complexation of diazaperylene and bisisoquinoline with transition metal ions in the gas phase studied by electrospray ionization mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3412 ◽

2008 ◽

Vol 22 (5) ◽

pp. 665-671 ◽

Cited By ~ 7

Author(s):

Ines Starke ◽

Stefan Kammer ◽

Nicolas Grunwald ◽

Uwe Schilde ◽

Hans-Jürgen Holdt ◽

...

Keyword(s):

Mass Spectrometry ◽

Transition Metal ◽

Metal Ions ◽

Electrospray Ionization ◽

Gas Phase ◽

Electrospray Ionization Mass Spectrometry ◽

Transition Metal Ions ◽

Ionization Mass Spectrometry ◽

Ionization Mass

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The Role of Divalent Transition Metal Ions in the Binding of Fur Dimer to DNA: Binding of Mn2+ and Co2+ to EC Fur dimer-DNA Complex

10.20944/preprints202011.0146.v4 ◽

2020 ◽

Author(s):

Mazen Hamed ◽

Salih Jabour

Keyword(s):

Dna Binding ◽

Transition Metal ◽

Metal Ions ◽

Conformational Changes ◽

Metal Ion ◽

Transition Metal Ions ◽

Rich Region ◽

Repressor Protein ◽

Dna Complex

Ferric uptake regulation protein is a repressor protein which binds an AT rich region of DNA (the iron box). Fur binds as a dimer in a helix turn helix mode and it is activated by iron(II) and other divalent transition metal ions at elevated concentrations in a process to regulate the ion uptake. Each transition metal ion induces certain conformational changes to aid the Fur binding, both the N-terminal and C-terminal domains take part in binding to DNA in addition to His 88 and His 86 residues. The process is discussed in view of experimental reports. Fe(II), Mn(II) and Co(II) activate Fur to bind DNA experimentally but Zinc plays a structural role and does not activate Fur to bind DNA.

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Oriented external electric fields as mimics for probing the role of metal ions and ligands in the thermal gas-phase activation of methane

Dalton Transactions ◽

10.1039/c8dt03048k ◽

2018 ◽

Vol 47 (43) ◽

pp. 15271-15277 ◽

Cited By ~ 9

Author(s):

Caiyun Geng ◽

Jilai Li ◽

Maria Schlangen ◽

Sason Shaik ◽

Xiaoyan Sun ◽

...

Keyword(s):

Transition Metal ◽

Metal Ions ◽

Metal Oxides ◽

Gas Phase ◽

Electric Fields ◽

Transition Metal Ions ◽

Simple Metal ◽

External Electric Fields

Unusual, if not unprecedented, effects of transition-metal ions and ligands are discovered when simple metal oxides or carbides activate methane in the gas phase in manners reminiscent of oriented external electric fields.

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The effect of partial exchange of sulphonated macroporous styrene-divinylbenzene copolymers for different ions on their catalytic activity

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc19812354 ◽

1981 ◽

Vol 46 (10) ◽

pp. 2354-2363 ◽

Cited By ~ 4

Author(s):

Svatomír Kmošták ◽

Karel Setínek

Keyword(s):

Catalytic Activity ◽

Transition Metal ◽

Metal Ions ◽

Gas Phase ◽

Transition Metal Ions ◽

Exchange Capacity ◽

Total Exchange Capacity ◽

Styrene Divinylbenzene ◽

Na Ions ◽

Type Of Transition

The catalytic activity of sulphonated macroporous styrene-divinylbenzene copolymers, the exchange capacity of which was neutralized from 30, 50 and 80% by Fe(III) ions and from 30% by Na ions and that of Wofatit Y-37 ion exchanger neutralized from 10% of its total exchange capacity by several transition metal ions and by sodium has been studied in isomerisation of cyclohexene and dehydration of 1-propanol in the gas phase at 130 °C. It was demonstrated that in both reactions transition metal ions exhibit additional effect to the expected neutralization of the polymer acid groups. In the case of cyclohexene isomerization, this effect depends on the degree of crosslinking of polymer mass of the catalyst. Such dependence has not been, however, observed in dehydration of 1-propanol. The type of transition metal ions did not exhibit any significant effect on the catalytic activity of the polymer catalysts studied.

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