Determination of low-level (sub-microgram) sulfur concentrations by isotope dilution multi-collector inductively couple plasma mass spectrometry using a 33S spike and internal normalization for mass bias correction

Timbal (Pb) adalah bahan toksik yang mudah terakumulasi dalam organ manusia dan dapat mengakibatkan gangguan kesehatan berupa anemia, gangguan fungsi ginjal, gangguan sistem syaraf, otak, dan kulit. Analisis kandungan logam berat Pb pada produk olahan susu diperlukan untuk mengetahui kelayakan konsumsi produk tersebut. Penelitian ini dilakukan pada bulan Juni-Agustus 2020 di Laboratorium. Tujuan penelitian ini untuk mengetahui kadar kontaminan logam berat Pb pada produk olahan susu yang berupa susu pasteurisasi, keju, mentega, dan yoghurt dengan metode Inductively Couple Plasma-Mass Spectrometry (ICP-MS). Preparasi sampel menggunakan metode destruksi basah dengan pelarut HNO3 65% ultrapur, H2O2 30% ultrapur dan HCl ultrapur. Kadar logam berat Pb yang diperoleh dari hasil penelitian yaitu produksi pertama pada sampel susu pasteurisasi < 0,001 mg/kg, keju < 0,001 mg/kg, mentega 0,004 mg/kg, yoghurt < 0,001 mg/kg, produksi kedua pada sampel susu pasteurisasi sebesar 0,020 mg/kg, keju 0,011 mg/kg, mentega 0,006 mg/kg, yoghurt 0,025 mg/kg, dan produksi ketiga pada sampel susu pasteurisasi < 0,001 mg/kg, keju 0,008 mg/kg, mentega < 0,001 mg/kg, yoghurt < 0,001 mg/kg. Hasil penelitian tersebut dibandingkan dengan Batas Maksimum Cemaran Logam Berat dalam Pangan menurut SNI 7387:2009 dan Peraturan BPOM No 23 Tahun 2017.

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Determination of zinc stable isotopes in biological materials using isotope dilution inductively coupled plasma mass spectrometry

Analytica Chimica Acta ◽

10.1016/0003-2670(92)85107-h ◽

1992 ◽

Vol 258 (2) ◽

pp. 317-324 ◽

Cited By ~ 14

Author(s):

Kristine Y. Patterson ◽

Claude Veillon ◽

Phylis B. Moser-Veillon ◽

Gordon F. Wallace

Keyword(s):

Mass Spectrometry ◽

Stable Isotopes ◽

Isotope Dilution ◽

Inductively Coupled Plasma ◽

Biological Materials ◽

Inductively Coupled ◽

Plasma Mass Spectrometry

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tudy on the determination of ¹⁰B/¹¹B isotope ratio in water samples by isotope dilution – inductively coupled plasma mass spectrometry (ID-ICPMS)

Nuclear Science and Technology ◽

10.53747/jnst.v7i3.99 ◽

2021 ◽

Vol 7 (3) ◽

pp. 8-16

Author(s):

Kim Dung Nguyen Thi ◽

Thi Lien Nguyen

Keyword(s):

Mass Spectrometry ◽

Isotope Dilution ◽

Water Samples ◽

Inductively Coupled Plasma ◽

Isotope Ratio ◽

Isotopic Ratio ◽

Primary Coolant ◽

Inductively Coupled ◽

Plasma Mass Spectrometry

The determination of 10B/11B isotope ratio and boron concentration in various watersamples using isotope dilution technique with inductively coupled plasma mass spectrometry (ICPMS) was studied. The interferences on precision and accuracy in isotopic ratio determination by ICPMS such as memory effects, dead time, spectral overlap of 12C were investigated for the selection of optimum conditions. By the addition of certain amounts of enriched 10B into samples, the 10B/11B ratio was determined through ICP-MS signal of 10B and 11B. The detection limit for 10B and 11B was experimentally obtained as 0.26 µg/L and 0.92 µg/L, respectively. The ratios of 10B/11B in measured water samples varied in the ranged between 0.1905 and 0.2484 for different matrices. This method has been then applied for the determination of boron isotopic ratio in VVER-1000 reactor-type simulated primary coolant water and in some environmental water samples.

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