Preparation of Maleimide‐Based Enediynes with Propargyl Ester for Efficient Tumor Cell Suppression

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A parallel and cascade controllable magnetofection system for synergistic tumor-association macrophage repolarization and tumor cell suppression in breast cancer treatment.


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A pH-sensitive acyclic enediyne (1) was synthesized for efficient DNA-cleavage and tumor cell suppression.


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