Maleimide-based acyclic enediyne for efficient DNA-cleavage and tumor cell suppression

2015 ◽  
Vol 3 (16) ◽  
pp. 3195-3200 ◽  
Author(s):  
Depeng Song ◽  
Shiyuan Sun ◽  
Yu Tian ◽  
Shuai Huang ◽  
Yun Ding ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Dna Cleavage ◽  
Ph Sensitive ◽  
Cell Suppression

A pH-sensitive acyclic enediyne (1) was synthesized for efficient DNA-cleavage and tumor cell suppression.

A parallel and cascade control system: magnetofection of miR125b for synergistic tumor-association macrophage polarization regulation and tumor cell suppression in breast cancer treatment

Nanoscale ◽  
2020 ◽  
Vol 12 (44) ◽  
pp. 22615-22627
Author(s):  
Ao Hu ◽  
Xiaobing Chen ◽  
Qunjie Bi ◽  
Yang Xiang ◽  
Rongrong Jin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Control System ◽  
Tumor Cell ◽  
Cancer Treatment ◽  
Macrophage Polarization ◽  
Breast Cancer Treatment ◽  
Cascade Control ◽  
Cell Suppression ◽  
Tumor Association ◽  
Cascade Control System

A parallel and cascade controllable magnetofection system for synergistic tumor-association macrophage repolarization and tumor cell suppression in breast cancer treatment.

An acyclic enediyne with a furyl tethering group for efficient inhibition of tumor cell viability

2015 ◽  
Vol 3 (43) ◽  
pp. 8584-8588 ◽  
Author(s):  
Depeng Song ◽  
Yu Tian ◽  
Shuai Huang ◽  
Baojun Li ◽  
Yuan Yuan ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Viability ◽  
Design Strategy ◽  
Ph Sensitive ◽  
Antitumor Antibiotics ◽  
Normal Cells

An acyclic enediyne with a furyl tethering group and two pH-sensitive orthoester groups at the alkynyl termini was synthesized. The introduction of a furyl tethering group represents a new design strategy of “intelligent” antitumor antibiotics that can distinguish tumor and normal cells.

scholarly journals Antioxidant and tumor cell suppression potential of Premna serratifolia Linn leaf

2012 ◽  
Vol 19 (1) ◽  
pp. 31 ◽  
Author(s):  
ThamizhN Selvam ◽  
SDamodar Kumar ◽  
V Venkatakrishnan ◽  
Preetham Elumalai
Keyword(s):  
Tumor Cell ◽  
Cell Suppression

Preparation of Maleimide‐Based Enediynes with Propargyl Ester for Efficient Tumor Cell Suppression

2020 ◽  
Vol 5 (23) ◽  
pp. 7069-7075
Author(s):  
Huimin Chen ◽  
Baojun Li ◽  
Mengsi Zhang ◽  
Haotian Lu ◽  
Yue Wang ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Suppression ◽  
Propargyl Ester

scholarly journals Tumor Cell Programmed Death Ligand 1-Mediated T Cell Suppression Is Overcome by Coexpression of CD80

2011 ◽  
Vol 186 (12) ◽  
pp. 6822-6829 ◽  
Author(s):  
Samuel T. Haile ◽  
Jacobus J. Bosch ◽  
Nnenna I. Agu ◽  
Annette M. Zeender ◽  
Preethi Somasundaram ◽  
...  
Keyword(s):  
T Cell ◽  
Tumor Cell ◽  
Programmed Death Ligand 1 ◽  
T Cell Suppression ◽  
Programmed Death ◽  
Cell Suppression

Enhanced Class I Tumor Antigen Presentation via Cytosolic Delivery of Exosomal Cargos by Tumor-Cell-Derived Exosomes Displaying a pH-Sensitive Fusogenic Peptide

2017 ◽  
Vol 14 (11) ◽  
pp. 4079-4086 ◽  
Author(s):  
Masaki Morishita ◽  
Yuki Takahashi ◽  
Makiya Nishikawa ◽  
Reiichi Ariizumi ◽  
Yoshinobu Takakura
Keyword(s):  
Tumor Cell ◽  
Antigen Presentation ◽  
Tumor Antigen ◽  
Ph Sensitive ◽  
Class I ◽  
Cytosolic Delivery

Both p53–PUMA/NOXA–Bax-mitochondrion and p53–p21cip1 pathways are involved in the CDglyTK-mediated tumor cell suppression

2009 ◽  
Vol 386 (4) ◽  
pp. 607-611 ◽  
Author(s):  
Zhendong Yu ◽  
Hao Wang ◽  
Libin Zhang ◽  
Aifa Tang ◽  
Qinna Zhai ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Suppression
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