Mikes, O.:High-Performance Liquid Chromatography of Biopolymers and Biooligomers. part B: Separation of individual Compound Classes (Journal of Chromatography Library Vol. 41B) XXI + 721 S. m. zahlr. Abb. u. Tab., ELSEVIER Amsterdam, Oxford, New York, Tokyo 1988, Preis Dfl. 399,00. ISBN 0-444-43034-2. Bezugsquellen: Europa: ELSEVIER SCIENCE PUBLISHERS, Sara Bürgerhartstraat 25, P.O. Box 211, 1000 AE Amsterdam, The Netherlands. USA u. Canada: ELSEVIER SCIENCE PUBLISHING COMPANY, 52 Vanderbilt Avenue, New York, NY 10017, USA.

1993 ◽  
Vol 45 (2) ◽  
pp. 79-79
Author(s):  
Schierbaum
Author(s):  
Li You-Qiong ◽  
Huang Hui-Ping ◽  
Chen Zhi-Zhong ◽  
Zhao Lin ◽  
Liang Liang ◽  
...  

AbstractHemoglobin (Hb) New York [β113 (G15) Val→Glu, GTG→GAG], also known as Hb Kaohsiung, is one of the most common Hb variants in South China. Currently, most used screening methods for hemoglobinopathies in South China are high performance liquid chromatography (HPLC) and capillary electrophoresis (CE). However, there is no study comparing the performance of CE and HPLC in the detection of Hb New York.In total 15 samples (including 13 adult blood samples and 2 cord blood samples) with heterozygous Hb New York were analyzed by CE and HPLC. Levels of Hb New York, HbAAll 15 cases (100%) were detected by CE, whereas none was detected by HPLC. Mean values of Hb New York and HbACE allows the detection of Hb New York, while this variant is not separated from Hb A on HPLC. CE may be the preferred method for hemoglobinopathy screening in areas with high prevalence of Hb New York.


Sign in / Sign up

Export Citation Format

Share Document