Gene delivery of bone morphogenetic protein-2 plasmid DNA promotes bone formation in a large animal model

2012 ◽  
Vol 8 (10) ◽  
pp. 763-770 ◽  
Author(s):  
Fiona Wegman ◽  
Ruth E. Geuze ◽  
Yvonne J. van der Helm ◽  
F. Cumhur Öner ◽  
Wouter J.A. Dhert ◽  
...  
Keyword(s):  
Animal Model ◽  
Gene Delivery ◽  
Bone Formation ◽  
Bone Morphogenetic Protein ◽  
Plasmid Dna ◽  
Bone Morphogenetic Protein 2 ◽  
Large Animal Model ◽  
Large Animal ◽  
Morphogenetic Protein

A doxycycline inducible, adenoviral bone morphogenetic protein-2 gene delivery system to bone

2017 ◽  
Vol 12 (1) ◽  
pp. e106-e118 ◽  
Author(s):  
Jennifer J. Bara ◽  
Iska Dresing ◽  
Stephan Zeiter ◽  
Martina Anton ◽  
Guy Daculsi ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Bone Morphogenetic Protein ◽  
Delivery System ◽  
Bone Morphogenetic Protein 2 ◽  
Gene Delivery System ◽  
Morphogenetic Protein

Bone formation promoted by bone morphogenetic protein-2 plasmid-loaded porous silica nanoparticles with the involvement of autophagy

Nanoscale ◽  
2019 ◽  
Vol 11 (45) ◽  
pp. 21953-21963 ◽  
Author(s):  
Xiaowei Xu ◽  
Maolei Sun ◽  
Dandan Wang ◽  
Wenhuan Bu ◽  
Zilin Wang ◽  
...  
Keyword(s):  
Bone Formation ◽  
Osteogenic Differentiation ◽  
Silica Nanoparticles ◽  
Bone Morphogenetic Protein ◽  
Porous Silica ◽  
Bone Morphogenetic Protein 2 ◽  
Calcium Deposition ◽  
Morphogenetic Protein

Bone morphogenetic protein-2 plasmid was encapsulated by polyethylenimine-modified porous silica nanoparticles, which promoted osteogenic differentiation and increased calcium deposition with the involvement of autophagy.

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