scholarly journals P03.13: The difference of NT-proBNP levels according to the type of congenital heart disease (CHD) in umbilical cord blood of newborns with prenatally diagnosed CHD

2013 ◽  
Vol 42 (s1) ◽  
pp. 122-122
Author(s):  
Y. Choo ◽  
H. Cha ◽  
W. Seong

2019 ◽  
Vol 40 (8) ◽  
pp. 1575-1583
Author(s):  
April D. Adams ◽  
Nimisha Aggarwal ◽  
Sara N. Iqbal ◽  
Lauren Tague ◽  
Kami Skurow-Todd ◽  
...  




2020 ◽  
Vol 59 ◽  
pp. 101318
Author(s):  
Laura Marzec ◽  
Eli T. Zettler ◽  
Clifford L. Cua ◽  
Brian K. Rivera ◽  
Sara Pasquali ◽  
...  


1996 ◽  
Vol 80 (2) ◽  
pp. 458-463 ◽  
Author(s):  
T. Reybrouck ◽  
L. Mertens ◽  
N. Kalis ◽  
M. Weymans ◽  
M. Dumoulin ◽  
...  

In pediatric exercise testing, conventional measures of aerobic exercise function such as maximal O2 uptake or the ventilatory anaerobic threshold (VAT) use only one value for the assessment of exercise capacity. We studied a more comprehensive approach to evaluate aerobic exercise function by analyzing the steepness of the slope of CO2 production (VCO2) vs. VO2 above the VAT (S3). This was calculated in 32 patients operated on for congenital heart disease [16 for transposition of the great arteries (TGA) and 16 for tetralogy of Fallot (TF)] and was compared with 16 age-matched controls (nl). The results show that the reproducibility of this new assessment method was excellent (coefficient of variation for S3: 8.6%). S3 was significantly steeper (P<0.05) in the patients (1.31 +/- 0.22 for TGA and 1.28 +/- 0.16 for TF) compared with the nl (1.10 +/- 0.22). Also, the difference between S3 and the slope of VCO2 vs. VO2 below the VAT was significantly higher in the patients (0.37 +/- 0.22 for TGA and 0.31 +/- 0.10 for TF) than in controls (0.22 +/- 0.06). The steeper slopes were associated with lower than normal values for VAT and O2 during exercise. It is concluded that the analysis of the steepness of the slope of CO2 is a sensitive, reproducible, and objective approach to evaluate the integrative cardiopulmonary response to exercise. It complements the assessment of a subnormal VAT by reflecting the extent of anaerobic metabolism.



2011 ◽  
Vol 9 (2) ◽  
pp. 207-211 ◽  
Author(s):  
Ricardo Barini ◽  
Ubirajara Costa Ferraz ◽  
Gregório Lorenzo Acácio ◽  
Isabela Nelly Machado

Objective: To assess the association between the time from umbilical cord blood collection until processing and the quality of the sample. Methods: Umbilical cord blood samples collected during the third stage of labor were placed in temperature-controlled boxes for the transport of biological material and sent to an umbilical cord blood bank, where the number of nucleated cells, viable cells and CD34+ cells were counted, and samples were additionally tested for contamination at the following time intervals: up to 24 hours, up to 48 hours and up to 72 hours following sampling. Data were analyzed using the multivariate analysis of variance (MANOVA) and compared using McNemar's χ2 test. Significance was defined at p < 0.05. Results: Means and medians of the number of nucleated cells, viable cells and CD34+ cells decreased significantly (p < 0.0001) as a function of the increased time between sampling and analysis, the difference between 24 and 48 hours being less than the difference between 24 and 72 hours. A linear correlation was found between the mean number of viable cells and CD34+ cells at the three moments of analysis. Contamination testing was negative in all samples. Conclusion: The increase in time interval from sampling until analysis negatively affected the number of nucleated cells, viable cells and CD34+ cells but was not associated with specimen contamination. A linear correlation was found between decrease in the number of viable cells and CD34+ cells.



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