Major Temporal and Spatial Patterns of Gene Expression during Differentiation of the Sea Urchin Embryo

1993 ◽  
Vol 155 (1) ◽  
pp. 216-234 ◽  
Author(s):  
Paul D. Kingsley ◽  
Lynne M. Angerer ◽  
Robert C. Angerer
1990 ◽  
Vol 32 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Koji Akasaka ◽  
Takayuki Ueda ◽  
Toru Higashinakagawa ◽  
Kazumi Yamada ◽  
Hiraku Shimada

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Huikang Tao ◽  
Pei Xie ◽  
Yuhang Cao ◽  
Liqi Shu ◽  
Liping Li ◽  
...  

Background. DNA demethylation, the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC), plays important roles in diverse biological processes and multiple diseases by regulating gene expression. Methods. In this study, utilizing DNA dot blot, immunofluorescence staining, and qRT-PCR, we studied the expression pattern of Tets, the enzymes governing DNA demethylation, and the levels of 5hmC, 5fC, and 5caC during the postnatal neuronal development of mice. Results. It was found that 5hmC, 5fC, and 5caC were highly enriched in multiple brain regions and aNSCs and displayed temporal and spatial patterns during postnatal neuronal development and the differentiation of aNSCs. Consistently, the expression of Tets also exhibited temporal and spatial patterns. Conclusion. DNA demethylation displayed dynamic features during postnatal neuronal development and the differentiation of aNSCs of mice, which could contribute to appropriate gene expression.


1995 ◽  
Vol 171 (2) ◽  
pp. 374-385 ◽  
Author(s):  
Keiji Inohaya ◽  
Shigeki Yasumasu ◽  
Mika Ishimaru ◽  
Akihiro Ohyama ◽  
Ichiro Iuchi ◽  
...  

2009 ◽  
Vol 180 (1) ◽  
pp. 151-160 ◽  
Author(s):  
Christophe M. R. LeMoine ◽  
Paul M. Craig ◽  
Kalindi Dhekney ◽  
Julie J. Kim ◽  
Grant B. McClelland

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