Transforming growth factor-β in T cell tolerance

Author(s):  
M. O. Li ◽  
Y. Laouar ◽  
Y. Peng ◽  
L. Gorelik ◽  
R. A. Flavell
Immunity ◽  
2009 ◽  
Vol 31 (1) ◽  
pp. 145-157 ◽  
Author(s):  
Roberto Tinoco ◽  
Victor Alcalde ◽  
Yating Yang ◽  
Karsten Sauer ◽  
Elina I. Zuniga

2000 ◽  
Vol 68 (11) ◽  
pp. 6505-6508 ◽  
Author(s):  
K. A. Wilkinson ◽  
T. D. Martin ◽  
S. M. Reba ◽  
H. Aung ◽  
R. W. Redline ◽  
...  

ABSTRACT Latency-associated peptide of transforming growth factor β (TGF-β) (LAP) was used to determine whether in vivo modulation of TGF-β bioactivity enhanced pulmonary immunity to Mycobacterium bovis BCG infection in C57BL/6 mice. LAP decreased BCG growth in the lung and enhanced antigen-specific T-cell proliferation and gamma interferon mRNA expression. Thus, susceptibility of the lung to primary BCG infection may be partially mediated by the immunosuppressive effects of TGF-β.


Immunity ◽  
2011 ◽  
Vol 34 (2) ◽  
pp. 201-212 ◽  
Author(s):  
Xing Chang ◽  
Fang Liu ◽  
Xiaofang Wang ◽  
Aiping Lin ◽  
Hongyu Zhao ◽  
...  

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