Bone Marrow Stem Cells in Clinical Application: Harnessing Paracrine Roles and Niche Mechanisms

2010 ◽  
pp. 265-292 ◽  
Author(s):  
Rania M. El Backly ◽  
Ranieri Cancedda
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Clinical Application ◽  
Bone Marrow Stem Cells

Bone marrow stem cells for the critical limb ischemia treatment: biological aspects and clinical application

2018 ◽  
Vol XIII (1) ◽  
Author(s):  
P. Orekhov ◽  
M. Konoplyannikov ◽  
V. Baklaushev ◽  
V. Kalsin ◽  
A. Averyanov ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Clinical Application ◽  
Critical Limb Ischemia ◽  
Limb Ischemia ◽  
Bone Marrow Stem Cells ◽  
Biological Aspects

Bone marrow stem cells make hepatocytes with replicative potential

2001 ◽  
Vol 120 (5) ◽  
pp. A62-A62
Author(s):  
S FORBES ◽  
M ALISON ◽  
K HODIVALADILKE ◽  
R JEFFERY ◽  
R POULSOM ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Bone Marrow Stem Cells

Autologous 5-azacytidine-cultured bone-marrow stem cells in surgical treatment of heart failure

2008 ◽  
Vol 7 ◽  
pp. 114-115
Author(s):  
R AKCHURIN ◽  
T RAKHMATZADE ◽  
E SKRIDLEVSKAYA ◽  
L SAMOYLENKO ◽  
V SERGIENKO ◽  
...  
Keyword(s):  
Heart Failure ◽  
Stem Cells ◽  
Bone Marrow ◽  
Surgical Treatment ◽  
Bone Marrow Stem Cells

Autologous bone marrow stem cells mediate paracrine axis in non-ischemic model of failing heart: A novel key mechanism?

2006 ◽  
Vol 54 (S 1) ◽  
Author(s):  
J Garbade ◽  
A Schubert ◽  
C Lipinski ◽  
H Aupperle ◽  
M Barten ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Autologous Bone Marrow ◽  
Bone Marrow Stem Cells ◽  
Failing Heart ◽  
Autologous Bone

CD34+ bone marrow stem cells homing to embolized rabbit lung tissue

2013 ◽  
Vol 32 (12) ◽  
pp. 1309-1314
Author(s):  
Jun GU ◽  
Song-shi NI ◽  
Hua HUANG
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Lung Tissue ◽  
Bone Marrow Stem Cells ◽  
Rabbit Lung

scholarly journals Investigating the Possibility of Intervertebral Disc Regeneration Induced by Granulocyte Colony Stimulating Factor-Stimulated Stem Cells in Rats

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Wen-Ching Tzaan ◽  
Hsien-Chih Chen
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Intervertebral Disc ◽  
Bone Marrow Stem Cells ◽  
Granulocyte Colony Stimulating Factor ◽  
Colony Stimulating Factor ◽  
Hematopoietic Stem ◽  
Disc Regeneration ◽  
Intervertebral Disc Regeneration ◽  
Stimulating Factor

Intervertebral disc (IVD) degeneration is a multifactorial process that is influenced by contributions from genetic predisposition, the aging phenomenon, lifestyle conditions, biomechanical loading and activities, and other health factors (such as diabetes). Attempts to decelerate disc degeneration using various techniques have been reported. However, to date, there has been no proven technique effective for broad clinical application. Granulocyte colony-stimulating factor (GCSF) is a growth factor cytokine that has been shown to enhance the availability of circulating hematopoietic stem cells to the brain and heart as well as their capacity for mobilization of mesenchymal bone marrow stem cells. GCSF also exerts significant increases in circulating neutrophils as well as potent anti-inflammatory effects. In our study, we hypothesize that GCSF can induce bone marrow stem cells differentiation and mobilization to regenerate the degenerated IVD. We found that GCSF had no contribution in disc regeneration or maintenance; however, there were cell proliferation within end plates. The effects of GCSF treatment on end plates might deserve further investigation.

scholarly journals Stem cells today: B1. Bone marrow stem cells

2004 ◽  
Vol 9 (5) ◽  
pp. 541-583 ◽  
Author(s):  
RG Edwards
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Bone Marrow Stem Cells
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