A Randomized, Placebo-Controlled Study of the Efficacy of Cognitive Intervention on Elderly People and on Patient’s with Alzheimer’s Disease

2006 ◽  
pp. 759-765
Author(s):  
J. J. Yanguas ◽  
C. Buiza ◽  
I. Etxeberria ◽  
N. Galdona ◽  
M. F. González ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Elderly People ◽  
Cognitive Intervention ◽  
Controlled Study

scholarly journals Intervenção cognitiva domiciliar para cuidadores de idosos com alzheimer

2018 ◽  
Vol 12 (10) ◽  
pp. 2659
Author(s):  
Ana Júlia De Souza Caparrol ◽  
Francine Golghetto Casemiro Golghetto Casemiro ◽  
Larissa Correa ◽  
Diana Quirino Monteiro ◽  
Marília Graciela Almeida Prado Sanchez ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Elderly People ◽  
Cognitive Intervention ◽  
Home Improvement ◽  
Before And After ◽  
Quasi Experimental ◽  
Student’S T ◽  
Improvement Intervention ◽  
Addenbrooke’S Cognitive Examination

RESUMO Objetivo: avaliar o efeito de intervenção cognitiva domiciliar sobre a cognição, a sobrecarga e o estresse em cuidadores de idosos com Doença de Alzheimer. Método: trata-se de estudo quantitativo, tipo quase-experimental, com 17 cuidadores informais de idosos com Doença de Alzheimer. Utilizaram-se o Addenbrooke’s Cognitive Examination-Revised (ACE-R), a Escala de Estresse Percebido (PSS) e a Escala de Sobrecarga de Zarit para a avaliação antes e depois da intervenção. Analisaram-se os resultados pelo SPSS, aplicando-se o test t de student para avaliar o efeito da intervenção. Resultados: identificaram-se mulheres (88,2%), com idade média de 52,5 anos e escolaridade média de 8,8 anos. Constatou-se melhora significativa na cognição geral pelo MEEM (p=0,008) e ACE-R (p= 0,003) e nos domínios atenção (p= 0,004), memória (p= 0,017) e fluência verbal (p= 0,023). Conclusão: avaliou-se pela intervenção cognitiva domiciliar melhora na cognição geral em cuidadores de idosos com Doença de Alzheimer, podendo ser uma importante ferramenta de promoção a saúde. Descritores: Idoso; Cuidadores; Cognição; Estresse Psicológico; Estudo de Intervenção, Geriatria.ABSTRACT Objective: to evaluate the effect of cognitive intervention on cognition, overload and stress in caregivers of elderly people with Alzheimer's disease. Method: this is a quasi-experimental quantitative study with 17 informal caregivers of elderly people with Alzheimer's disease. The Addenbrooke's Cognitive Examination-Revised (ACE-R), Perceived Stress Scale (PSS) and Zarit's Overload Scale were used for the evaluation before and after the intervention. The results were analyzed by the SPSS, applying the Student's t-test to evaluate the effect of the intervention. Results: women (88.2%) were identified, with a mean age of 52.5 years and mean schooling of 8.8 years. It was found a significant improvement in the general cognition by the MEEM (p = 0.008) and ACE-R (p = 0.003) and in the attention domains (p = 0.004), memory (p = 0.017) and verbal fluency (p = 0.023). Conclusion: it was evaluated by the cognitive home improvement intervention in general cognition in caregivers of elderly people with Alzheimer's disease, and can be an important tool to promote health. Descriptors: Aged; Caregivers; Cognition; Stress, Psychological; Clinical Trial; Geriatrics.RESUMEN Objetivo: evaluar el efecto de intervención cognitiva domiciliaria sobre la cognición, la sobrecarga y el estrés en cuidadores de ancianos con enfermedad de Alzheimer. Método: se trata de un estudio cuantitativo, tipo casi-experimental, con 17 cuidadores informales de ancianos con enfermedad de Alzheimer. Se utilizaron el Addenbrooke's Cognitive Examination-Revised (ACE-R), la Escala de estrés percibido (PSS) y la escala de sobrecarga de Zarit para la evaluación antes y después de la intervención. Se analizaron los resultados por el SPSS, aplicándose el test t de student para evaluar el efecto de la intervención. Resultados: se identificaron mujeres (88,2%), con edad media de 52,5 años y escolaridad promedio de 8,8 años. Se observó una mejora significativa en la cognición general por el MEEM (p = 0,008) y ACE-R (p = 0,003) y en los dominios atención (p = 0,004), memoria (p = 0,017) y fluencia verbal (p = 0,023). Conclusión: se evaluó por la intervención cognitiva domiciliaria mejora en la cognición general en cuidadores de ancianos con Enfermedad de Alzheimer, pudiendo ser una importante herramienta de promoción a la salud. Descriptores: Anciano; Cuidadores; Cognición; Estrés Psicológico; Ensayo Clínico; Geriatria.

scholarly journals Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study

2012 ◽  
Vol 4 (5) ◽  
pp. 43 ◽  
Author(s):  
John M Ringman ◽  
Sally A Frautschy ◽  
Edmond Teng ◽  
Aynun N Begum ◽  
Jenny Bardens ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo

Influence of Educational Attainment on Cognition-Based Intervention Programs for Persons with Mild Alzheimer’s Disease

2016 ◽  
Vol 22 (5) ◽  
pp. 577-582 ◽  
Author(s):  
Israel Contador ◽  
Bernardino Fernández-Calvo ◽  
Francisco Ramos ◽  
Javier Olazarán
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Decline ◽  
Effect Size ◽  
Study Groups ◽  
Total Sample ◽  
Cognitive Intervention ◽  
Potential Effect ◽  
Cognitive Status ◽  
Disease Assessment

AbstractObjectives: This research retrospectively analyzed the effect of education on cognitive interventions carried out in patients with mild Alzheimer’s disease (AD). Methods: The total sample consisted of 75 patients with mild AD receiving treatment with cholinesterase inhibitors. The participants were divided into two groups: cognitive intervention (IG; n=45) and waiting list (WLG; n=30). Patients in the IG received either the Big Brain Academy (n=15) or the Integrated Psychostimulation Program (n=30) during 12 weeks. The influence of education on intervention effect was analyzed comparing mean change scores of the two study groups in the cognitive subscale of the Alzheimer’s Disease Assessment Scale (ADAS-cog), stratified by educational level. The potential effect of age, sex, cognitive status, and type of intervention was examined using post hoc stratification analyses. Results: Higher education was associated with faster cognitive decline in the WLG (effect size=0.51; p<.01). However, cognitive evolution was not influenced by education in the IG (effect size=0.12; p=.42). Conclusions: Our results suggest that cognitive intervention might delay accelerated cognitive decline in higher educated individuals with mild AD. (JINS, 2016, 23, 1–6)

scholarly journals The health of elderly people bearing Alzheimer’s disease: an integrative review / Saúde do idoso com doença de Alzheimer: revisão integrativa

2018 ◽  
Vol 10 (4) ◽  
pp. 941
Author(s):  
Hemmily Nóbrega Ventura ◽  
Leila De Cássia Tavares da Fonseca ◽  
Bruno César Fernandes Borges ◽  
Jéssica Yasmine Lacerda Nóbrega ◽  
Herbert Nóbrega Ventura ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Elderly People ◽  
Integrative Review

Objetivo: Verificar o conhecimento produzido pelos pesquisadores a respeito da saúde do idoso com Doença de Alzheimer (DA). Métodos: Revisão integrativa da literatura com levantamento bibliográfico realizado na Biblioteca Virtual em Saúde (BVS), MEDLINE e nos bancos de dados do Portal de Periódicos Capes.  Resultados: Observou-se a incipiência de artigos científicos publicados sobre a Doença de Alzheimer com enfoque na saúde da pessoa idosa. Conclusão: Verificou-se a necessidade de pesquisas para investigar a saúde do idoso em face à doença de Alzheimer que possibilitem aporte teórico na elaboração de políticas públicas de saúde mais abrangentes para os cuidados aos idosos. Descritores: Envelhecimento, Doença de Alzheimer, Autonomia pessoal, Saúde do idoso.

A randomized controlled study on effects of ibuprofen on cognitive progression of Alzheimer’s disease

2009 ◽  
Vol 21 (2) ◽  
pp. 102-110 ◽  
Author(s):  
Patrizio Pasqualetti ◽  
Cristina Bonomini ◽  
Gloria Dal Forno ◽  
Luca Paulon ◽  
Elena Sinforiani ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Randomized Controlled

Effectiveness of procedural memory stimulation in mild Alzheimer's disease patients: A controlled study

2001 ◽  
Vol 11 (3-4) ◽  
pp. 263-272 ◽  
Author(s):  
Orazio Zanetti ◽  
Gabriele Zanieri ◽  
Giuseppina Di Giovanni ◽  
Luc Pietre De Vreese ◽  
Alessandra Pezzini ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Procedural Memory ◽  
Controlled Study
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