Synthetic Opioids

2018 ◽  
pp. 353-381 ◽  
Author(s):  
Patrick M. Beardsley ◽  
Yan Zhang
Keyword(s):  
Synthetic Opioids

The Evolving Overdose Epidemic: Synthetic Opioids And Rising Stimulant-Related Harms

2020 ◽  
Author(s):  
Christopher M Jones ◽  
Faraah Bekheet ◽  
Ju Nyeong Park ◽  
G Caleb Alexander
Keyword(s):  
Illicit Drug ◽  
Opioid Overdose ◽  
Prescription Opioids ◽  
Drug Supply ◽  
Synthetic Opioids ◽  
Key Stakeholders ◽  
Public Health Challenges ◽  
Concomitant Exposure ◽  
Over Time ◽  
Key Questions

Abstract The opioid overdose epidemic is typically described as having occurred in three waves, with morbidity and mortality accruing over time principally from prescription opioids (1999-2010), heroin (2011-2013) and illicit fentanyl and other synthetic opioids (2014-present). However, the increasing presence of synthetic opioids mixed into the illicit drug supply, including with stimulants such as cocaine and methamphetamine, as well as rising stimulant-related deaths, reflects the rapidly evolving nature of the overdose epidemic posing urgent and novel public health challenges. We synthesize the evidence underlying these trends, consider key questions such as where and how concomitant exposure to fentanyl and stimulants is occurring, and identify actions for key stakeholders regarding how these emerging threats, and continued evolution of the overdose epidemic, can best be addressed.

Blood concentrations of new synthetic opioids

2021 ◽  
Author(s):  
Piotr Adamowicz ◽  
Karolina Nowak
Keyword(s):  
Blood Concentrations ◽  
Synthetic Opioids

Quantification of seven novel synthetic opioids in blood using LC–MS/MS

2018 ◽  
Vol 37 (1) ◽  
pp. 215-223 ◽  
Author(s):  
Janna Lowry ◽  
Michael T. Truver ◽  
Madeleine J. Swortwood
Keyword(s):  
Synthetic Opioids ◽  
Novel Synthetic Opioids

scholarly journals Detection of Fentanyl Analogs and Synthetic Opioids in Real Hair Samples

2018 ◽  
Vol 43 (4) ◽  
pp. 259-265 ◽  
Author(s):  
Alberto Salomone ◽  
Joseph J Palamar ◽  
Rachele Bigiarini ◽  
Enrico Gerace ◽  
Daniele Di Corcia ◽  
...  
Keyword(s):  
Synthetic Opioids ◽  
Hair Samples ◽  
Fentanyl Analogs

scholarly journals Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace

2018 ◽  
Vol 134 ◽  
pp. 101-107 ◽  
Author(s):  
Michael H. Baumann ◽  
Susruta Majumdar ◽  
Valerie Le Rouzic ◽  
Amanda Hunkele ◽  
Rajendra Uprety ◽  
...  
Keyword(s):  
Recreational Drug ◽  
Pharmacological Characterization ◽  
Synthetic Opioids ◽  
Novel Synthetic Opioids

Quantitative Analysis of Novel Synthetic Opioids, Morphine and Buprenorphine in Oral Fluid by LC–MS-MS

2018 ◽  
Vol 42 (8) ◽  
pp. 554-561 ◽  
Author(s):  
Michael T Truver ◽  
Madeleine J Swortwood
Keyword(s):  
Quantitative Analysis ◽  
Oral Fluid ◽  
Synthetic Opioids ◽  
Novel Synthetic Opioids

scholarly journals America’s Failing Trade War With China: A Focus on Fentanyl

2021 ◽  
Vol 8 (2) ◽  
pp. 171-182
Author(s):  
Corinna K. Hamilton
Keyword(s):  
Economic Interdependence ◽  
Prescription Opioids ◽  
State Governments ◽  
People's Republic Of China ◽  
Republic Of China ◽  
Trade Relations ◽  
Synthetic Opioids ◽  
History Of ◽  
Trade War ◽  
The U.S

As this article will explain in detail, much of the fentanyl reaching the hands of Americans comes from The People’s Republic of China (“China”). However, as seen by the rise in overdoses, most efforts to control the invasion of fentanyl have been unsuccessful. Although the federal and state governments have attempted to curtail this crisis by imposing sanctions and urging China to regulate production and shipping of the substance, fentanyl continues to flood the streets of the U.S. Moreover, the economic interdependence between the two nations complicates the matter. Because of this interdependence, the U.S. must take control of the situation. The U.S. fentanyl problem will persist if Americans are not dissuaded from using the drug. We must focus on the demand, rather than the supply. This comment focuses on the rise of opioids and synthetic pain relievers, and the variety of attempts at decreasing the number of addicts and overdoses. Initially, the comment will discuss the history of the popular drug opium, opiates, and prescription opioids, discussing state and federal attempts at curbing the crisis that the U.S. faces. It will address the rise of synthetic opioids, such as fentanyl, and how and why it was created. Section two will discuss how fentanyl and its precursors are imported into the U.S. from China. Section three will discuss U.S. federal and state attempts at legislation to control the flow of fentanyl into the U.S. Section four will address the implications, or perhaps fuel to the fire, that the influx in the supply of fentanyl from China has had on trade relations, and how the trade linkage between the two nations obfuscates the situation. The comment will conclude by hypothesizing how the U.S. and China will recalibrate their relationship and recommend that to combat the fentanyl emergency, the U.S. needs to take steps to offer Americans with drug addictions the assistance they need.

scholarly journals Confirmation of Carfentanil, U-47700 and Other Synthetic Opioids in a Human Performance Case by LC–MS-MS

2017 ◽  
Vol 41 (6) ◽  
pp. 493-497 ◽  
Author(s):  
Joshua Seither ◽  
Lisa Reidy
Keyword(s):  
Human Performance ◽  
Synthetic Opioids

The Biological Activity of Designer Drugs from the Group of Synthetic Opioids

2021 ◽  
Vol 11 (2) ◽  
pp. 186-197
Author(s):  
A. I. Golovko ◽  
Ju. Ju. Ivnitsky ◽  
M. B. Ivanov ◽  
V. L. Rejniuk ◽  
V. K. Kozlov
Keyword(s):  
Biological Activity ◽  
Designer Drugs ◽  
Synthetic Opioids
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