An operational computer aided software environment: ILIADE

Author(s):  
Marie -Gabrielle Bloch
1987 ◽  
Vol 24 (03) ◽  
pp. 246-264
Author(s):  
Michael G. Parsons ◽  
Klaus-Peter Beier

The rapid evolution of the microcomputer has changed the software needs of today's naval architects. The Department of Naval Architecture and Marine Engineering at The University of Michigan has been a leader in the application of computers in ship design education. The computer environment readily available to the department's students has changed dramatically in the past few years with the evolution of the Computer-Aided Marine Design Laboratory within the department and the creation of the Computer Aided Engineering Network (CAEN) within the College of Engineering. The microcomputer facilities available to the students are briefly described. To fully integrate this capability into the department's curriculum, a coordinated suite of computer-aided ship design software has been developed for use on the Macintosh and IBM-PC/XT/AT microcomputers provided for the students. To support the use of this and other software on a wide range of computers, a portable, device-independent computer graphics subprogram package M-PLOT has been developed. The educational philosophy behind this design software and its scope, capabilities, and use in ship design education are described. Examples of the use of selected programs are presented to illustrate these capabilities. Plans for further work are outlined. The effort is well toward the goal of a complete, microcomputer-based ship design software environment.


Author(s):  
E.T. Agaev ◽  
◽  
A.Yu. Bekmeshov ◽  

The article discusses the method of improving the quality of computer-aided design of machine-building products based on the introduction of the concept of 3D drawing. A comparative analysis of the application of a 3D drawing and the use of a standard flat drawing for the manufacture of machine-building profile products on modern CNC machines is given. The 3D drawings of the products are developed in the SolidWorks software environment. Based on the analysis, it is concluded that the use of 3D drawings in compliance with their correct representation in computer-aided design systems will reduce the time for the manufacture of relevant parts.


1991 ◽  
Vol 30 (01) ◽  
pp. 23-29 ◽  
Author(s):  
A. S. Rigby

During the last decade there has been a wealth of papers discussing the development of scoring systems in medicine, some of which have led to fully operational computer-aided diagnostic systems. In this paper we sketch the development of a simple scoring system for one of the more common rheumatic diseases, rheumatoid arthritis (RA) using a two-tier model, independence Bayes’ followed by logistic discrimination. The scoring system gives reasonably well calibrated probability estimates of RA which suggests ways in which the development of computerised systems in rheumatology might be approached.


Author(s):  
Mark Ellisman ◽  
Maryann Martone ◽  
Gabriel Soto ◽  
Eleizer Masliah ◽  
David Hessler ◽  
...  

Structurally-oriented biologists examine cells, tissues, organelles and macromolecules in order to gain insight into cellular and molecular physiology by relating structure to function. The understanding of these structures can be greatly enhanced by the use of techniques for the visualization and quantitative analysis of three-dimensional structure. Three projects from current research activities will be presented in order to illustrate both the present capabilities of computer aided techniques as well as their limitations and future possibilities.The first project concerns the three-dimensional reconstruction of the neuritic plaques found in the brains of patients with Alzheimer's disease. We have developed a software package “Synu” for investigation of 3D data sets which has been used in conjunction with laser confocal light microscopy to study the structure of the neuritic plaque. Tissue sections of autopsy samples from patients with Alzheimer's disease were double-labeled for tau, a cytoskeletal marker for abnormal neurites, and synaptophysin, a marker of presynaptic terminals.


Author(s):  
Greg V. Martin ◽  
Ann L. Hubbard

The microtubule (MT) cytoskeleton is necessary for many of the polarized functions of hepatocytes. Among the functions dependent on the MT-based cytoskeleton are polarized secretion of proteins, delivery of endocytosed material to lysosomes, and transcytosis of integral plasma membrane (PM) proteins. Although microtubules have been shown to be crucial to the establishment and maintenance of functional and structural polarization in the hepatocyte, little is known about the architecture of the hepatocyte MT cytoskeleton in vivo, particularly with regard to its relationship to PM domains and membranous organelles. Using an in situ extraction technique that preserves both microtubules and cellular membranes, we have developed a protocol for immunofluorescent co-localization of cytoskeletal elements and integral membrane proteins within 20 µm cryosections of fixed rat liver. Computer-aided 3D reconstruction of multi-spectral confocal microscope images was used to visualize the spatial relationships among the MT cytoskeleton, PM domains and intracellular organelles.


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